Skip to main content
Top
Published in: Current Infectious Disease Reports 6/2010

01-11-2010

Clinical Spectrum of Desquamative Inflammatory Vaginitis

Author: Colleen Kennedy Stockdale

Published in: Current Infectious Disease Reports | Issue 6/2010

Login to get access

Abstract

Desquamative inflammatory vaginitis (DIV) is a rare chronic clinical syndrome of unknown etiology characterized by profuse purulent vaginal discharge, diffuse exudative vaginitis, epithelial cell exfoliation, and pain. A diagnosis of DIV is often missed by even experienced practitioners owing to its rarity and its clinical and laboratory presentation similar to other inflammatory vulvovaginal disorders. Although DIV is difficult to treat and often requires long-term therapy for maintenance, successful therapy has been reported with topical steroids and clindamycin.
Literature
1.
go back to reference Nyirjesy P, Peyton C, Weitz MV, et al.: Causes of chronic vaginitis. Obstet Gynecol 2006, 108:1185–1191.PubMed Nyirjesy P, Peyton C, Weitz MV, et al.: Causes of chronic vaginitis. Obstet Gynecol 2006, 108:1185–1191.PubMed
2.
go back to reference Scheffey LC, Rakoff AE, Lang WR: An unusual case of exudative vaginitis (hydrorrhea vaginalis) treated with local hydrocortisone. Am J Obstet Gynecol 1956, 72:208–211.PubMed Scheffey LC, Rakoff AE, Lang WR: An unusual case of exudative vaginitis (hydrorrhea vaginalis) treated with local hydrocortisone. Am J Obstet Gynecol 1956, 72:208–211.PubMed
3.
go back to reference Gray LA, Barnes ML: Vaginitis in women, diagnosis and treatment. Am J Obstet Gynecol 1965, 92:125–127.PubMed Gray LA, Barnes ML: Vaginitis in women, diagnosis and treatment. Am J Obstet Gynecol 1965, 92:125–127.PubMed
4.
go back to reference Gardner HL: Desquamative inflammatory vaginitis: a newly defined entity. Am J Obstet Gynecol 1968, 102:1102–1105.PubMed Gardner HL: Desquamative inflammatory vaginitis: a newly defined entity. Am J Obstet Gynecol 1968, 102:1102–1105.PubMed
5.
go back to reference Lynch P: Desquamative inflammatory vaginitis with oral lichen planus. Presented at the Second International Congress of the International Society for the Study of Vulvar Disease. Key Biscayne, Florida: January 9–11, 1975. Lynch P: Desquamative inflammatory vaginitis with oral lichen planus. Presented at the Second International Congress of the International Society for the Study of Vulvar Disease. Key Biscayne, Florida: January 9–11, 1975.
6.
go back to reference Edwards L, Friedrich EG: Desquamative vaginitis: lichen planus in disguise. Obstet Gynecol 1988, 71:832–836.PubMed Edwards L, Friedrich EG: Desquamative vaginitis: lichen planus in disguise. Obstet Gynecol 1988, 71:832–836.PubMed
7.
go back to reference Oates JD, Rowen D: Desquamative inflammatory vaginitis. A review. Genitourin Med 1990, 66:275–279.PubMed Oates JD, Rowen D: Desquamative inflammatory vaginitis. A review. Genitourin Med 1990, 66:275–279.PubMed
8.
go back to reference Sobel JD: Desquamative inflammatory vaginitis: a new subgroup of purulent vaginitis responsive to topical 2% clindamycin therapy. Am J Obstet Gynecol 1994, 171:1215–1220.PubMed Sobel JD: Desquamative inflammatory vaginitis: a new subgroup of purulent vaginitis responsive to topical 2% clindamycin therapy. Am J Obstet Gynecol 1994, 171:1215–1220.PubMed
9.
go back to reference Peacocke M, Djurkinak E, Thys-Jacobs S: Treatment of desquamative inflammatory vaginitis with vitamin D: A case report. Cutis 2008, 81:75–78.PubMed Peacocke M, Djurkinak E, Thys-Jacobs S: Treatment of desquamative inflammatory vaginitis with vitamin D: A case report. Cutis 2008, 81:75–78.PubMed
10.
go back to reference Edwards L: Desquamative inflammatory vaginitis. In Genital Dermatology Atlas. Edited by Edwards L. Philadelphia: Lippincott Williams & Wilkins; 2004:237–240. Edwards L: Desquamative inflammatory vaginitis. In Genital Dermatology Atlas. Edited by Edwards L. Philadelphia: Lippincott Williams & Wilkins; 2004:237–240.
11.
go back to reference Ledger WJ, Witkin SS: Desquamative inflammatory vaginitis. In Vulvovaginal Infections. Edited by Ledger WJ, Witkin SS. London: Manson Publishing; 2007:49–52. Ledger WJ, Witkin SS: Desquamative inflammatory vaginitis. In Vulvovaginal Infections. Edited by Ledger WJ, Witkin SS. London: Manson Publishing; 2007:49–52.
12.
go back to reference Lev-Sagie A, Nyirjesy P: Treatment of desquamative inflammatory vaginitis (DIV) with intravaginal 2% clindamycin cream: a long term follow-up. J Low Genit Tract Dis 2009, 13(5 Suppl):S2. Lev-Sagie A, Nyirjesy P: Treatment of desquamative inflammatory vaginitis (DIV) with intravaginal 2% clindamycin cream: a long term follow-up. J Low Genit Tract Dis 2009, 13(5 Suppl):S2.
14.
15.
go back to reference • Murphy R, Edwards L: Desquamative inflammatory vaginitis, what is it? J Reprod Med 2008, 53:124–128. The authors report the histopathology findings of idiopathic DIV. PubMed • Murphy R, Edwards L: Desquamative inflammatory vaginitis, what is it? J Reprod Med 2008, 53:124–128. The authors report the histopathology findings of idiopathic DIV. PubMed
16.
go back to reference Nyirjesy P: Postmenopausal vaginitis. Curr Infect Dis Rep 2007, 9:480–484.CrossRef Nyirjesy P: Postmenopausal vaginitis. Curr Infect Dis Rep 2007, 9:480–484.CrossRef
17.
go back to reference Newbern EC, Foxman B, Leaman D, Sobel JD: Desquamative inflammatory vaginitis: an exploratory case-control study. Ann Epidemiol 2002, 12:346–352.CrossRefPubMed Newbern EC, Foxman B, Leaman D, Sobel JD: Desquamative inflammatory vaginitis: an exploratory case-control study. Ann Epidemiol 2002, 12:346–352.CrossRefPubMed
18.
go back to reference • Reichman R, Sobel JD: Desquamative inflammatory vaginitis (DIV): twelve year experience with one hundred and thirty patients—new insights. J Low Genit Tract Dis 2009, 13(5 Suppl):S2. The authors presented preliminary findings on the largest cohort of women with DIV. • Reichman R, Sobel JD: Desquamative inflammatory vaginitis (DIV): twelve year experience with one hundred and thirty patients—new insights. J Low Genit Tract Dis 2009, 13(5 Suppl):S2. The authors presented preliminary findings on the largest cohort of women with DIV.
19.
go back to reference Fowler RS: Expansion of altered vaginal flora states in vaginitis to include a spectrum of microflora. J Reprod Med 2007, 52:93–99.PubMed Fowler RS: Expansion of altered vaginal flora states in vaginitis to include a spectrum of microflora. J Reprod Med 2007, 52:93–99.PubMed
20.
go back to reference Donders GGG, Vereecken A, Bosmans E, et al.: Definition of a type of abnormal vaginal flora that is distince from bacterial vaginosis: aerobic vaginitis. BJOG 2002, 109:34–43.CrossRefPubMed Donders GGG, Vereecken A, Bosmans E, et al.: Definition of a type of abnormal vaginal flora that is distince from bacterial vaginosis: aerobic vaginitis. BJOG 2002, 109:34–43.CrossRefPubMed
21.
go back to reference Dennerstein G, Scurry J, Brenan J, et al: Desquamative inflammatory vaginitis. In The Vulva and Vagina Manual. Edited by Dennerstein G, Scurry J, Brenan J, et al. Australia: Gynederm Publishing; 2005:170–172. Dennerstein G, Scurry J, Brenan J, et al: Desquamative inflammatory vaginitis. In The Vulva and Vagina Manual. Edited by Dennerstein G, Scurry J, Brenan J, et al. Australia: Gynederm Publishing; 2005:170–172.
22.
go back to reference Jacobson M, Krumholz B, Franks A: Desquamative inflammatory vaginitis. J Reprod Med 1989, 34(9):647–650.PubMed Jacobson M, Krumholz B, Franks A: Desquamative inflammatory vaginitis. J Reprod Med 1989, 34(9):647–650.PubMed
Metadata
Title
Clinical Spectrum of Desquamative Inflammatory Vaginitis
Author
Colleen Kennedy Stockdale
Publication date
01-11-2010
Publisher
Current Science Inc.
Published in
Current Infectious Disease Reports / Issue 6/2010
Print ISSN: 1523-3847
Electronic ISSN: 1534-3146
DOI
https://doi.org/10.1007/s11908-010-0135-y

Other articles of this Issue 6/2010

Current Infectious Disease Reports 6/2010 Go to the issue