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Current HIV/AIDS Reports
Published in: Current HIV/AIDS Reports 1/2014

01-03-2014 | HIV Pathogenesis and Treatment (AL Landay, Section Editor)

Metabolic Consequences of HIV: Pathogenic Insights

Authors: Amanda L. Willig, E. Turner Overton

Published in: Current HIV/AIDS Reports | Issue 1/2014

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Abstract

With the advances in antiretroviral therapy (ART), HIV infection has been transformed into a chronic medical condition that can be effectively managed like diabetes or hypertension. For HIV care providers, the focus of care for many patients has shifted from prevention of opportunistic infection and AIDS-related conditions to age-related cardiometabolic comorbidities, including cardiovascular disease, diabetes, obesity, and frailty. Numerous reports have highlighted that these diseases are occurring at an earlier age among HIV-infected persons. However, there is an ongoing debate regarding the role of HIV infection, ART, and other factors that may underlie the accelerated occurrence of these diseases. Herein, we review the epidemiology of the US HIV epidemic with regards to several metabolic comorbidities and address mechanisms that likely contribute to the current nature of HIV disease.
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Metadata
Title
Metabolic Consequences of HIV: Pathogenic Insights
Authors
Amanda L. Willig
E. Turner Overton
Publication date
01-03-2014
Publisher
Springer US
Published in
Current HIV/AIDS Reports / Issue 1/2014
Print ISSN: 1548-3568
Electronic ISSN: 1548-3576
DOI
https://doi.org/10.1007/s11904-013-0191-7

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