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Current Heart Failure Reports
Published in: Current Heart Failure Reports 4/2015

01-08-2015 | Pathophysiology of Myocardial Failure (I Anand and M Patarroyo-Aponte, Section Editors)

Autonomic Regulation Therapy in Heart Failure

Authors: Una Buckley, Kalyanam Shivkumar, Jeffrey L. Ardell

Published in: Current Heart Failure Reports | Issue 4/2015

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Abstract

Autonomic regulation therapy (ART) is a rapidly emerging therapy in the management of congestive heart failure secondary to systolic dysfunction. Modulation of the cardiac neuronal hierarchy can be achieved with bioelectronics modulation of the spinal cord, cervical vagus, baroreceptor, or renal nerve ablation. This review will discuss relevant preclinical and clinical research in ART for systolic heart failure. Understanding mechanistically what is being stimulated within the autonomic nervous system by such device-based therapy and how the system reacts to such stimuli is essential for optimizing stimulation parameters and for the future development of effective ART.
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Metadata
Title
Autonomic Regulation Therapy in Heart Failure
Authors
Una Buckley
Kalyanam Shivkumar
Jeffrey L. Ardell
Publication date
01-08-2015
Publisher
Springer US
Published in
Current Heart Failure Reports / Issue 4/2015
Print ISSN: 1546-9530
Electronic ISSN: 1546-9549
DOI
https://doi.org/10.1007/s11897-015-0263-7
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