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Current Gastroenterology Reports
Published in: Current Gastroenterology Reports 10/2015

01-10-2015 | Pediatric Gastroenterology (S Orenstein, Section Editor)

Meta-Analysis-Based Guidance for Dietary Management in Eosinophilic Esophagitis

Author: Alfredo J. Lucendo

Published in: Current Gastroenterology Reports | Issue 10/2015

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Abstract

Eosinophilic esophagitis (EoE) is a prevalent chronic esophageal disorder, triggered and maintained by immunologically mediated responses against dietary antigens. EoE represents the most recent form of food allergy, and its control by avoiding offending foods has increasingly appeared as a therapeutic alternative to achieve and maintain remission. Dietary therapies have proved equally effective in pediatric and adult EoE patients, among whom various types of interventions to eliminate or reduce food antigens exposure have been evaluated. A recent meta-analysis showed elemental diet as the most effective option to induce disease remission, but with a limited application in clinical practice. Inconsistency and wide variability in results from skin allergy testing-directed food restriction contributed to dissatisfaction with implementation of this option, which subsequently was displaced by empiric elimination of common food allergens. Such empiric elimination of common food allergens is now recognized as the best alternative for dietary treatment, with moderate-to-high efficiency and reproducible results. This review provides evidence-based insights into the dietary management of EoE.
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Metadata
Title
Meta-Analysis-Based Guidance for Dietary Management in Eosinophilic Esophagitis
Author
Alfredo J. Lucendo
Publication date
01-10-2015
Publisher
Springer US
Published in
Current Gastroenterology Reports / Issue 10/2015
Print ISSN: 1522-8037
Electronic ISSN: 1534-312X
DOI
https://doi.org/10.1007/s11894-015-0464-y

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