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Current Cardiology Reports
Published in: Current Cardiology Reports 3/2016

Open Access 01-03-2016 | Interventional Cardiology (S Rao, Section Editor)

Intracoronary Imaging in the Detection of Vulnerable Plaques

Authors: Jonathan A. Batty, Shristy Subba, Peter Luke, Li Wing Chi Gigi, Hannah Sinclair, Vijay Kunadian

Published in: Current Cardiology Reports | Issue 3/2016

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Abstract

Coronary artery disease is the result of atherosclerotic changes to the coronary arterial wall, comprising endothelial dysfunction, vascular inflammation and deposition of lipid-rich macrophage foam cells. Certain high-risk atherosclerotic plaques are vulnerable to disruption, leading to rupture, thrombosis and the clinical sequelae of acute coronary syndrome. Though recognised as the gold standard for evaluating the presence, distribution and severity of atherosclerotic lesions, invasive coronary angiography is incapable of identifying non-stenotic, vulnerable plaques that are responsible for adverse cardiovascular events. The recognition of such limitations has impelled the development of intracoronary imaging technologies, including intravascular ultrasound, optical coherence tomography and near-infrared spectroscopy, which enable the detailed evaluation of the coronary wall and atherosclerotic plaques in clinical practice. This review discusses the present status of invasive imaging technologies; summarises up-to-date, evidence-based clinical guidelines; and addresses questions that remain unanswered with regard to the future of intracoronary plaque imaging.
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Metadata
Title
Intracoronary Imaging in the Detection of Vulnerable Plaques
Authors
Jonathan A. Batty
Shristy Subba
Peter Luke
Li Wing Chi Gigi
Hannah Sinclair
Vijay Kunadian
Publication date
01-03-2016
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 3/2016
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-016-0705-1

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