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Current Bladder Dysfunction Reports

Published in:

14-01-2022 | Constipation | Neurogenic Bladder (C Powell, Section Editor)

Role of Pelvic Organ Crosstalk in Dysfunction of the Bowel and Bladder

Authors: Sanjay Sinha, Pawan Vasudeva, Sirish Bharadwaj, Ankur Mittal

Published in: Current Bladder Dysfunction Reports | Issue 2/2022

Abstract

Purpose of Review

The distal large bowel and urinary bladder are contiguous pelvic organs that share a common embryological origin with potential interaction in health and disease. Literature on the subject remains disorganized and largely unrecognized by clinical guidelines. Understanding this interaction could potentially improve patient outcomes.

Recent Findings

The bladder and bowel interact by several mechanisms that can be broadly classified as peripheral neural, spinal central, supraspinal central, and non-neuronal. In vivo studies show that experimental insults in one organ induce changes in behavior of the other. Laboratory studies have better defined the pathways that underlie these interactions. Clinical data shows an association between bowel and bladder symptoms in a wide spectrum of patient populations. Management of these bowel symptoms could potentially improve lower urinary tract symptoms in the clinical setting. Current clinical guidelines, such as the American Urological Association Guidelines for Overactive Bladder, European Society of Pediatric Urology Guidelines for Pediatric Neurogenic Bladder, European Association of Urology Neuro-Urology Guidelines, or the UK National Institute for Health and Care Excellence Guidelines on Urinary Incontinence and Pelvic Organ Prolapse, need to take better cognizance of this relationship.

Summary

Dysfunctions of the bowel and bladder commonly co-exist. While this interaction occurs at multiple levels, much work remains to be done to improve our understanding especially with regard to management of bowel dysfunction to specifically improve lower urinary tract symptoms.

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Title: Role of Pelvic Organ Crosstalk in Dysfunction of the Bowel and Bladder
Authors: Sanjay Sinha
Pawan Vasudeva
Sirish Bharadwaj
Ankur Mittal
Publication date: 14-01-2022
Publisher: Springer US
Keywords: Constipation
Overactive Bladder
Urinary Incontinence
Nerve Stimulation
Constipation
Urinary Incontinence
Published in: Current Bladder Dysfunction Reports / Issue 2/2022
Print ISSN: 1931-7212
Electronic ISSN: 1931-7220
DOI: https://doi.org/10.1007/s11884-022-00645-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Role of Pelvic Organ Crosstalk in Dysfunction of the Bowel and Bladder

Abstract

Purpose of Review

Recent Findings

Summary

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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