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Current Atherosclerosis Reports

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01-12-2018 | Women and Ischemic Heart Disease (A. Maran, Section Editor)

Sex-Based Differences in Chronic Total Occlusion Management

Authors: Amy Cheney, Kathleen E. Kearney, William Lombardi

Published in: Current Atherosclerosis Reports | Issue 12/2018

Abstract

ᅟ

Chronic total occlusions (CTOs) are an important and increasingly recognized subgroup of coronary lesions, documented in at least 30%, but up to 52% of patients with coronary artery disease (CAD) undergoing coronary angiography. Percutaneous coronary intervention (PCI) of these lesions is increasingly pursued, with excellent success rates.

Purpose of Review

It is known that gender differences exist in the presentation of CAD, as well as in clinical outcomes after routine PCI; however, it is not well described how these differences pertain to management of CTOs. This review summarizes the available data regarding sex-based differences in CTO management and outcomes.

Recent Findings

Women comprise approximately 20% of CTO registry and trial participants.

Summary

As has been demonstrated in PCI studies, women comprise a minority of patients in CTO PCI registries and trials. Sex-based differences exist in complication rates, collateral formation, and outcomes and need further evaluation in future studies.

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Title: Sex-Based Differences in Chronic Total Occlusion Management
Authors: Amy Cheney
Kathleen E. Kearney
William Lombardi
Publication date: 01-12-2018
Publisher: Springer US
Published in: Current Atherosclerosis Reports / Issue 12/2018
Print ISSN: 1523-3804
Electronic ISSN: 1534-6242
DOI: https://doi.org/10.1007/s11883-018-0760-8

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Purpose of Review

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