A Review on Atherosclerotic Biology, Wall Stiffness, Physics of Elasticity, and Its Ultrasound-Based Measurement | springermedicine.com

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Current Atherosclerosis Reports

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01-12-2016 | Vascular Biology (J. Hamilton, Section Editor)

A Review on Atherosclerotic Biology, Wall Stiffness, Physics of Elasticity, and Its Ultrasound-Based Measurement

Authors: Anoop K. Patel, Harman S. Suri, Jaskaran Singh, Dinesh Kumar, Shoaib Shafique, Andrew Nicolaides, Sanjay K. Jain, Luca Saba, Ajay Gupta, John R. Laird, Argiris Giannopoulos, Jasjit S. Suri

Published in: Current Atherosclerosis Reports | Issue 12/2016

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Abstract

Functional and structural changes in the common carotid artery are biomarkers for cardiovascular risk. Current methods for measuring functional changes include pulse wave velocity, compliance, distensibility, strain, stress, stiffness, and elasticity derived from arterial waveforms. The review is focused on the ultrasound-based carotid artery elasticity and stiffness measurements covering the physics of elasticity and linking it to biological evolution of arterial stiffness. The paper also presents evolution of plaque with a focus on the pathophysiologic cascade leading to arterial hardening. Using the concept of strain, and image-based elasticity, the paper then reviews the lumen diameter and carotid intima-media thickness measurements in combined temporal and spatial domains. Finally, the review presents the factors which influence the understanding of atherosclerotic disease formation and cardiovascular risk including arterial stiffness, tissue morphological characteristics, and image-based elasticity measurement.

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Title: A Review on Atherosclerotic Biology, Wall Stiffness, Physics of Elasticity, and Its Ultrasound-Based Measurement
Authors: Anoop K. Patel
Harman S. Suri
Jaskaran Singh
Dinesh Kumar
Shoaib Shafique
Andrew Nicolaides
Sanjay K. Jain
Luca Saba
Ajay Gupta
John R. Laird
Argiris Giannopoulos
Jasjit S. Suri
Publication date: 01-12-2016
Publisher: Springer US
Published in: Current Atherosclerosis Reports / Issue 12/2016
Print ISSN: 1523-3804
Electronic ISSN: 1534-6242
DOI: https://doi.org/10.1007/s11883-016-0635-9

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