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Current Allergy and Asthma Reports
Published in: Current Allergy and Asthma Reports 8/2015

01-08-2015 | Rhinosinusitis (M Mullol, Section Editor)

Humoral Primary Immunodeficiencies in Chronic Rhinosinusitis

Authors: Smriti Nayan, Reza Alizadehfar, Martin Desrosiers

Published in: Current Allergy and Asthma Reports | Issue 8/2015

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Abstract

Chronic rhinosinusitis (CRS) may be the primary presenting symptom for primary immunodeficiencies (PID). PID can affect the humoral or the cellular immune system. This paper provides an overview of PID which affect the humoral immune system, with details around the diagnostic criteria, the epidemiology, the subtypes, the clinical manifestations, underlying molecular mechanisms, methods to screen for PID and the management of CRS in the context of PID. A high clinical suspicion of PID is required when assessing patients with CRS who are refractory to maximal medical therapy.
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Metadata
Title
Humoral Primary Immunodeficiencies in Chronic Rhinosinusitis
Authors
Smriti Nayan
Reza Alizadehfar
Martin Desrosiers
Publication date
01-08-2015
Publisher
Springer US
Published in
Current Allergy and Asthma Reports / Issue 8/2015
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-015-0547-8

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