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Irish Journal of Medical Science (1971 -)

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01-11-2021 | COVID-19 | Letter to the Editor

Prevalence of dry mouth in COVID-19 patients with and without Sicca syndrome in a large hospital center

Author: Joseph Katz

Published in: Irish Journal of Medical Science (1971 -) | Issue 4/2021

Excerpt

The ACE-2 receptor is abundantly expressed on the epithelial cells of the salivary glands, and when infected by SARS-CoV2, these receptors are over expressed [1]. It is speculated that signaling of the ACE-2 receptor by the virus triggers a cascade of inflammatory processes, ending in acute and chronic sialoadenitis and causing disruption in salivary secretion and dry mouth [2, 3]. …

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Fantozzi PJ, Pampena E, Di Vanna D, Pellegrino E, Corbi D, Mammucari S, Alessi F, Pampena R, Bertazzoni G, Minisola S, Mastroianni CM, Polimeni A, Romeo U, Villa A (2020) Xerostomia, gustatory and olfactory dysfunctions in patients with COVID-19. Am J Otolaryngol 41(6):102721. https://doi.org/10.1016/j.amjoto.2020.102721CrossRefPubMedPubMedCentral

Chen L, Zhao J, Peng J, Li X, Deng X, Geng Z, Shen Z, Guo F, Zhang Q, Jin Y, Wang L, Wang S (2020) Detection of SARS-CoV-2 in saliva and characterization of oral symptoms in COVID-19 patients. Cell Prolif 19:e12923. https://doi.org/10.1111/cpr.12923CrossRef

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Huang PI, Lin TC, Liu FC, Ho YJ, Lu JW, Lin TY (2020) Positive anti-SSA/Ro antibody in a woman with SARS-CoV-2 infection using immunophenotyping: a case report. Medicina (Kaunas) 56(10):521. https://doi.org/10.3390/medicina56100521CrossRef

Fujii H, Tsuji T, Yuba T, Tanaka S, Suga Y, Matsuyama A, Omura A, Shiotsu S, Takumi C, Ono S, Horiguchi M, Hiraoka N (2020) High levels of anti-SSA/Ro antibodies in COVID-19 patients with severe respiratory failure: a case-based review: high levels of anti-SSA/Ro antibodies in COVID-19. Clin Rheumatol 39(11):3171–3175. https://doi.org/10.1007/s10067-020-05359-yCrossRefPubMed

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11.

Favalli EG, Monti S, Ingegnoli F, Balduzzi S, Caporali R, Montecucco C (2020) Incidence of COVID-19 in patients with rheumatic diseases treated with targeted immunosuppressive drugs: what can we learn from observational data? [published online ahead of print, 2020 Jun 7]. Arthritis Rheum. https://doi.org/10.1002/art.41388

12.

Figueroa-Parra G, Aguirre-Garcia GM, Gamboa-Alonso CM, Camacho-Ortiz A, Galarza-Delgado DA (2020) Are my patients with rheumatic diseases at higher risk of COVID-19? Ann Rheum Dis 79(6):839–840. https://doi.org/10.1136/annrheumdis-2020-217322CrossRefPubMed

13.

Rodríguez Y, Novelli L, Rojas M et al (2020) Autoinflammatory and autoimmune conditions at the crossroad of COVID-19. J Autoimmun 114:102506. https://doi.org/10.1016/j.jaut..102506CrossRefPubMedPubMedCentral

Title: Prevalence of dry mouth in COVID-19 patients with and without Sicca syndrome in a large hospital center
Author: Joseph Katz
Publication date: 01-11-2021
Publisher: Springer International Publishing
Keyword: COVID-19
Published in: Irish Journal of Medical Science (1971 -) / Issue 4/2021
Print ISSN: 0021-1265
Electronic ISSN: 1863-4362
DOI: https://doi.org/10.1007/s11845-020-02480-4

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