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Published in: Irish Journal of Medical Science (1971 -) 1/2019

01-02-2019 | Original Article

Difference in intraocular pressure measurements between non-contact tonometry and Goldmann applanation tonometry and the role of central corneal thickness in affecting glaucoma referrals

Authors: Khalid Kamel, Edward Dervan, Kevin Falzon, Colm O’Brien

Published in: Irish Journal of Medical Science (1971 -) | Issue 1/2019

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Abstract

Background

Patients at glaucoma risk are commonly identified by optometrists and subsequently referred to glaucoma specialists. Optometrists mainly use non-contact tonometry (NCT) for intraocular pressure (IOP) measurement.

Aims

To investigate the role of differences in IOP measurement between NCT and Goldmann applanation tonometry (GAT) and the effect of central corneal thickness (CCT) on these differences in optometrist referrals

Methods

Details of the initial clinical visit of patients referred with IOP > 21 mmHg in either eye as measured by NCT to a consultant glaucoma specialist were retrospectively reviewed. Demographic and referral data, IOP, CCT, and glaucoma diagnosis were obtained. The main outcome measure was the IOP measurement differences between NCT and GAT.

Results

Of the 98 patients referred, only 23% had IOP > 21 mmHg when measured by GAT. NCT (Nidek NT400, Reichert Puff, Pulsair Easy Eye) measured the IOP greater than GAT by a mean of 5.8 mmHg (NCT 24.1 ± 3.5, GAT 18.3 ± 3.0). The effect of CCT on IOP measurement was less for GAT (R2 0.034, p = 0.067) than for NCT (R2 0.088, p = 0.003). The NCT/GAT IOP differences increased with increasing CCT (R2 0.166, p < 0.0001). The NCT/GAT differences decreased with patient age (R2 0.048, p = 0.03). Patients were classified as normal 67% (66/98), ocular hypertension 11% (11/98), glaucoma suspect 14% (14/98), and glaucoma 7% (7/98).

Conclusions

The difference in IOP measurement between NCT and GAT leads to a possible increase in glaucoma referrals, particularly in patients with thicker corneas. Repeat IOP using GAT and CCT measurement would help in triaging referrals.
Literature
4.
go back to reference Bhan A, Browning AC, Shah S, Hamilton R, Dave D, Dua HS (2002) Effect of corneal thickness on intraocular pressure measurements with the pneumotonometer, Goldmann applanation tonometer, and Tono-Pen. Invest Ophthalmol Vis Sci 43(5):1389–1392PubMed Bhan A, Browning AC, Shah S, Hamilton R, Dave D, Dua HS (2002) Effect of corneal thickness on intraocular pressure measurements with the pneumotonometer, Goldmann applanation tonometer, and Tono-Pen. Invest Ophthalmol Vis Sci 43(5):1389–1392PubMed
8.
go back to reference Whitacre MM, Stein RA, Hassanein K (1993) The effect of corneal thickness on applanation tonometry. Am J Ophthalmol 115(5):592–596CrossRef Whitacre MM, Stein RA, Hassanein K (1993) The effect of corneal thickness on applanation tonometry. Am J Ophthalmol 115(5):592–596CrossRef
10.
go back to reference Bell RW, O'Brien C (1997) The diagnostic outcome of new glaucoma referrals. Ophthalmic Physiol Opt 17(1):3–6CrossRefPubMed Bell RW, O'Brien C (1997) The diagnostic outcome of new glaucoma referrals. Ophthalmic Physiol Opt 17(1):3–6CrossRefPubMed
11.
go back to reference Bell RW, O'Brien C (1997) Accuracy of referral to a glaucoma clinic. Ophthalmic Physiol Opt 17(1):7–11CrossRefPubMed Bell RW, O'Brien C (1997) Accuracy of referral to a glaucoma clinic. Ophthalmic Physiol Opt 17(1):7–11CrossRefPubMed
12.
go back to reference Sheldrick JH, Ng C, Austin DJ, Rosenthal AR (1994) An analysis of referral routes and diagnostic accuracy in cases of suspected glaucoma. Ophthalmic Epidemiol 1(1):31–39CrossRefPubMed Sheldrick JH, Ng C, Austin DJ, Rosenthal AR (1994) An analysis of referral routes and diagnostic accuracy in cases of suspected glaucoma. Ophthalmic Epidemiol 1(1):31–39CrossRefPubMed
13.
go back to reference Theodossiades J, Murdoch I (1999) Positive predictive value of optometrist-initiated referrals for glaucoma. Ophthalmic Physiol Opt 19(1):62–67CrossRefPubMed Theodossiades J, Murdoch I (1999) Positive predictive value of optometrist-initiated referrals for glaucoma. Ophthalmic Physiol Opt 19(1):62–67CrossRefPubMed
19.
go back to reference Henson DB, Harper RA (1998) Do non contact tonometers read high? Ophthalmic Physiol Opt 18(3):308–310CrossRefPubMed Henson DB, Harper RA (1998) Do non contact tonometers read high? Ophthalmic Physiol Opt 18(3):308–310CrossRefPubMed
Metadata
Title
Difference in intraocular pressure measurements between non-contact tonometry and Goldmann applanation tonometry and the role of central corneal thickness in affecting glaucoma referrals
Authors
Khalid Kamel
Edward Dervan
Kevin Falzon
Colm O’Brien
Publication date
01-02-2019
Publisher
Springer London
Published in
Irish Journal of Medical Science (1971 -) / Issue 1/2019
Print ISSN: 0021-1265
Electronic ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-018-1795-0

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