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01-08-2020 | Statins

Communicating cardiovascular risk to high-risk cancer survivors: a mixed-methods pilot study of a statin risk communication tool

Authors: Nirupa J. Raghunathan, Emily C. Zabor, Nassim Anderson, Kevin Oeffinger, Emily S. Tonorezos, Deborah Korenstein

Published in: Journal of Cancer Survivorship | Issue 4/2020

Abstract

Purpose

Childhood, adolescent, and young adult cancer survivors treated with radiation therapy (RT) may be unaware of their high cardiovascular disease (CVD) risk or how to mitigate it. Tools are needed to improve understanding. We developed and pilot-tested a risk communication tool for shared decision-making with survivors regarding CVD risk reduction with statin therapy. We included quantitative and qualitative arms to further tool development and testing.

Methods

The statin risk communication tool was adapted from a previously validated tool. Patients were at increased risk for CVD due to history of chest RT and recruited to usual care and intervention arms. The post-visit survey included Likert-like scales to explore acceptability of the tool, knowledge questions, and a decisional conflict scale. This pilot study used descriptive statistics and was not powered for significance. Semi-structured interviews with intervention arm participants explored shared decision-making processes.

Results

Median participant (n = 46) age was 45. Most intervention patients (22/24, 92%) and 50% (11/22) of controls found statin information acceptable while 31% (7/22) of the control arm selected “not applicable” regarding information acceptability. Most participants were unaware of their personal CVD risk or potential statin side effects. In semi-structured interviews, participants found the tool is helpful to visualize risk and aid conversations.

Conclusions

The risk communication tool was acceptable. Qualitative data suggested the tool improved decisional clarity and comfort.

Implications for Cancer Survivors

Poor knowledge of CVD and statins and poor recall of CVD risk conversation suggest a need to continue to optimize conversations regarding cardiovascular risk and statin therapy.

Available only for authorised users

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Title: Communicating cardiovascular risk to high-risk cancer survivors: a mixed-methods pilot study of a statin risk communication tool
Authors: Nirupa J. Raghunathan
Emily C. Zabor
Nassim Anderson
Kevin Oeffinger
Emily S. Tonorezos
Deborah Korenstein
Publication date: 01-08-2020
Publisher: Springer US
Keyword: Statins
Published in: Journal of Cancer Survivorship / Issue 4/2020
Print ISSN: 1932-2259
Electronic ISSN: 1932-2267
DOI: https://doi.org/10.1007/s11764-020-00860-4

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Abstract

Purpose

Methods

Results

Conclusions

Implications for Cancer Survivors

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