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General Thoracic and Cardiovascular Surgery

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01-11-2014 | Case Report

Aortic valve replacement in an elderly patient with factor XI deficiency

Authors: Suguru Watanabe, Tadanori Minagawa, Tomoaki Kagatani, Makoto Miura, Kouichi Tabayashi

Published in: General Thoracic and Cardiovascular Surgery | Issue 11/2014

Abstract

Factor XI (FXI) deficiency is rare and associated with bleeding after surgical procedures. We report a case of an 80-year-old woman with severe aortic valve stenosis. FXI deficiency was diagnosed due to prolonged activated partial thromboplastin time. Aortic valve replacement was performed using a porcine bioprosthetic valve. Intra-operation bleeding was controlled by the transfusion of a fresh frozen plasma. The postoperative course was uneventful.

Duga S, Salomon O. Factor XI deficiency. Semin Thromb Hemost. 2009;35:416–25.PubMedCrossRef

Seligsohn U. Factor XI deficiency in humans. J Tromb Haemost. 2009;7:84–7.CrossRef

Bolton-Maggs PH. Factor XI deficiency and its management. Haemophilia. 2000;6:100–9.PubMedCrossRef

The research of requirement coagulation factor products for coagulopathy in Japan 2010. Tokyo: Blood products research organization; 2010. p. 1–2.

MacKinlay N, Taper J, Renisson F, Rickard K. Cardiac surgery and catheterization in patients with haemophilia. Haemophilia. 2000;6:84–8.PubMedCrossRef

Vander Woude JC, Milam JD, Walker WE, Houchin DP, Weiland AP, Cooley DA. Cardiovascular surgery in patients with congenital plasma coagulopathies. Ann Thorac Surg. 1988;46:283–8.PubMedCrossRef

Brunken R, Follette D, Wittig J. Coronary artery bypass in hereditary factor XI deficiency. Ann Thorac Surg. 1984;38:406–8.PubMedCrossRef

Livnat T, Tamarin I, Mor Y, Winckler H, Horowitz Z, Korianski Y, et al. Recombinant activated factor VII and tranexamic acid are haemostatically effective during major surgery in factor XI-deficient patients with inhibitor antibodies. Thromb Haemost. 2009;102(3):487–92.PubMed

Schulman S. Pharmacologic tools to reduce bleeding in surgery. Hematology. 2012;1:517–21.

10.

Nowell J, Wilton E, Markus H, Jahangiri M. Antithrombotic therapy following bioprosthetic aortic valve replacement. Eur J Cardiothorac Surg. 2007;31:578–85.PubMedCrossRef

Title: Aortic valve replacement in an elderly patient with factor XI deficiency
Authors: Suguru Watanabe
Tadanori Minagawa
Tomoaki Kagatani
Makoto Miura
Kouichi Tabayashi
Publication date: 01-11-2014
Publisher: Springer Japan
Published in: General Thoracic and Cardiovascular Surgery / Issue 11/2014
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI: https://doi.org/10.1007/s11748-013-0271-z

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Aortic valve replacement in an elderly patient with factor XI deficiency

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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