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Internal and Emergency Medicine
Published in: Internal and Emergency Medicine 7/2019

01-10-2019 | Cardiopulmonary Resuscitation | THE CUTTING EDGE: RESEARCH UPDATE

Assessment of epinephrine efficacy in out-of-hospital cardiac arrest

Authors: Mattia Bonzi, Jacopo Peta, Alessandra Fusco, Paola Bosco, Gruppo di Autoformazione Metodologica (GrAM)

Published in: Internal and Emergency Medicine | Issue 7/2019

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Excerpt

Epinephrine has been a cornerstone of cardiac resuscitation for over 50 years and continues to be recommended by the recent updates of the advanced life support guidelines. However, there is limited evidence about its effects on survival and neurologic outcomes [1]. …
Literature
1.
Link MS, Berkow LC, Kudenchuk PJ, Halperin HR, Hess EP, Moitra VK et al (2015) Part 7: Adult advanced cardiovascular life support: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 132:S444–S464CrossRefPubMed
2.
Lin S, Callaway CW, Shah PS, Wagner JD, Beyene J, Ziegler CP et al (2014) Adrenaline for out-of-hospital cardiac arrest resuscitation: a systematic review and meta-analysis of randomized controlled trials. Resuscitation 85:732–740CrossRefPubMed
3.
Hagihara A, Hasegawa M, Abe T, Nagata T, Wakata Y, Miyazaki S (2012) Prehospital epinephrine use and survival among patients with out-of-hospital cardiac arrest. JAMA 307:1161CrossRefPubMed
4.
Perkins GD, Ji C, Deakin CD, Quinn T, Nolan JP, Scomparin C et al (2018) A randomized trial of epinephrine in out-of-hospital cardiac arrest. N Engl J Med 379:711–721CrossRefPubMed
Metadata
Title
Assessment of epinephrine efficacy in out-of-hospital cardiac arrest
Authors
Mattia Bonzi
Jacopo Peta
Alessandra Fusco
Paola Bosco
Gruppo di Autoformazione Metodologica (GrAM)
Publication date
01-10-2019
Publisher
Springer International Publishing
Published in
Internal and Emergency Medicine / Issue 7/2019
Print ISSN: 1828-0447
Electronic ISSN: 1970-9366
DOI
https://doi.org/10.1007/s11739-019-02158-5

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