Published in:
01-08-2018 | Research Letter to the Editor
Changes in global longitudinal strain in renal transplant recipients following 12 months of exercise
Authors:
Minetti Enrico, Riggs Klika, Chiara Ingletto, Gabriele Mascherini, Gianni Pedrizzetti, Laura Stefani
Published in:
Internal and Emergency Medicine
|
Issue 5/2018
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Excerpt
Renal transplant recipients (RTR) patients are at elevated risk for cardiac dysfunction prior to transplantation due to existing comorbidities such as diabetes, hypertension, and sedentary behavior [
1], and are at increased cardiovascular (CV) mortality risk following surgery due to multiple drug therapies, immunosuppression, and further physical inactivity following surgery [
2]. As such, early detection of cardiac pathology and monitoring of function is warranted in order to provide safe and appropriate therapy. Among the non-invasive methods to assess myocardial function, echocardiographic strain is increasingly recognized as an effective technique to investigate cardiac performance. Global longitudinal strain (GLS) has been demonstrated to be the most direct, valid and reliable tool for the assessment of left ventricular (LV) function [
3], and may also be used to identify sub-clinical LV dysfunction in potential cardiomyopathies [
4]. …