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01-09-2015 | Original Article

Robotic-assisted radical prostatectomy is less stressful than the open approach: results of a contemporary prospective study evaluating pathophysiology of cortisol stress-related kinetics in prostate cancer surgery

Authors: Antonio B. Porcaro, Alberto Molinari, Alessandro Terrin, Nicolò De Luyk, Roberto Baldassarre, Matteo Brunelli, Stefano Cavalleri, Maria Angela Cerruto, Matteo Gelati, Gian Luca Salvagno, Gian Cesare Guidi, Walter Artibani

Published in: Journal of Robotic Surgery | Issue 3/2015

Abstract

The objective of this study was to investigate the effects of prostate cancer (PCA) surgery on the stress system and to identify potential independent factors associating with stress recovery. The design of the study was prospective and PCA surgery included robot-assisted radical prostatectomy (RARP) or retro pubic radical prostatectomy. Between February and December 2013, 151 consecutive patients were evaluated. The effects of PCA surgery on the stress system were measured by cortisol serum levels before and after surgery on post-operative day (POD) 0, 1, 3, 5 and 45. Statistical methods were applied. RARP was performed in 71 % of cases. PCA surgery triggered the stress system which immediately (POD 0) responded by cortisol overproduction which induced the negative feedback mechanism that started on POD 1, continued on POD.

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Title: Robotic-assisted radical prostatectomy is less stressful than the open approach: results of a contemporary prospective study evaluating pathophysiology of cortisol stress-related kinetics in prostate cancer surgery
Authors: Antonio B. Porcaro
Alberto Molinari
Alessandro Terrin
Nicolò De Luyk
Roberto Baldassarre
Matteo Brunelli
Stefano Cavalleri
Maria Angela Cerruto
Matteo Gelati
Gian Luca Salvagno
Gian Cesare Guidi
Walter Artibani
Publication date: 01-09-2015
Publisher: Springer London
Published in: Journal of Robotic Surgery / Issue 3/2015
Print ISSN: 1863-2483
Electronic ISSN: 1863-2491
DOI: https://doi.org/10.1007/s11701-015-0522-3

At a glance: The STEP trials

Springer Medicine

Robotic-assisted radical prostatectomy is less stressful than the open approach: results of a contemporary prospective study evaluating pathophysiology of cortisol stress-related kinetics in prostate cancer surgery

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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