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Obesity Surgery
Published in: Obesity Surgery 10/2020

01-10-2020 | Obesity | Original Contributions

Laparoscopic Sleeve Gastrectomy Affects Coagulation System of Obese Patients

Authors: Chen Liu, Ziliang Han, Nengwei Zhang, Jirun Peng, Bin Zhu, Buhe Amin, Dexiao Du, Wei Yan, Dongdong Zhang, Ke Gong

Published in: Obesity Surgery | Issue 10/2020

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Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) is nowadays the most popular bariatric procedure for obesity. However, whether LSG increases the risk of thrombosis remains unclear. The aim of this study was to investigate potential effects of LSG on coagulation system.

Methods

Fifty-five obese patients underwent LSG between 2016 and 2018. The LSG was performed with pneumoperitoneum pressure maintained at 13 mmHg. Venous blood specimens were collected from each patient before surgery, at the end of pneumoperitoneum (i.e., 0 h after surgery), and at 24 h after surgery to determine prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB), platelet count (PLT), D-dimer (D-D), red blood cell count (RBC), hematocrit (HCT), plateletcrit (PCT), cholesterol (CHOL), triglyceride (TRIG), and serum calcium (Ca). All patients were examined on the veins of the lower limbs by color Duplex sonography (CDS) before surgery and at 24 h after surgery, respectively.

Results

All patients successfully underwent LSG. No severe surgery-related complications were observed during 1-month follow-up after operation. Preoperative BMI was 43.6 ± 8.3 kg/m2. The levels of coagulation factors were within the normal range before surgery, except a relatively higher PLT. The PT and D-D were increased at 0 h and 24 h after surgery (P < 0.05), whereas APTT was decreased (P < 0.05). The postoperative FIB remained similar to the preoperative one (P > 0.05). The CDS identified no thrombus in the veins of the lower limbs, either before surgery or at 24 h after surgery.

Conclusions

LSG may cause postoperative hypercoagulability of patients with obesity.
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Metadata
Title
Laparoscopic Sleeve Gastrectomy Affects Coagulation System of Obese Patients
Authors
Chen Liu
Ziliang Han
Nengwei Zhang
Jirun Peng
Bin Zhu
Buhe Amin
Dexiao Du
Wei Yan
Dongdong Zhang
Ke Gong
Publication date
01-10-2020
Publisher
Springer US
Published in
Obesity Surgery / Issue 10/2020
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-020-04769-w

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