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Published in: Obesity Surgery 4/2020

01-04-2020 | Food Intolerance | New Concept

Roux-en-Y Gastric Bypass Reversal: A Novel Technique With Functional Reversal – Case Series

Authors: Kamran Shah, Hjörtur Gislason

Published in: Obesity Surgery | Issue 4/2020

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Abstract

Background

Reversal of Roux-en-Y gastric bypass (RYGB) to normal anatomy (NA) is mandated in selected cases. However, reversal operations are associated with high complication rates and long operative times. In this study, we present the functional reversal (FR) as a novel method and an alternative to reversal to NA in treating the otherwise intractable symptoms rarely occurring after RYGB.

Methods

This is a retrospective cohort study of RYGB-patients with symptoms resistant to non-surgical treatment. Placement of gastrostomy tube for surgical evaluation and optimization of patients was usually done before FR. Resolution of symptoms was assessed along with efficacy and safety of the procedure. Achieved results were compared with data from the literature pertaining to reversal to NA.

Settings

High-volume bariatric center, Norway.

Results

Ten patients underwent FR. Mean follow-up after reversal was 18.4 months. Symptoms leading to operation improved in all patients. Eight patients suffered from hypoglycemia; resolution was seen in six and improvement of symptoms in the remaining two. Food intolerance, early dumping, nausea, postprandial abdominal pain, and malnutrition were alleviated in all patients. One leak was seen. Mean surgical time was 35.2 min. Total weight loss (TWL) and excess weight loss (EWL) after index RYGB were reduced 4.5% and 17.8%.

Conclusion

Functional reversal looks promising as an alternative to reversal to normal anatomy as it is technically simpler and safer and seems at least as effective in treating otherwise refractory symptoms.
Literature
1.
go back to reference Mason EE, Ito C. Gastric bypass in obesity. Surg Clin North Am. 1967;47:1345–51.CrossRef Mason EE, Ito C. Gastric bypass in obesity. Surg Clin North Am. 1967;47:1345–51.CrossRef
2.
go back to reference Colquitt JL, Pickett K, Loveman E, et al. Surgery for weight loss in adults. Cochrane Database Syst Rev, CD003641. 2014;8 Colquitt JL, Pickett K, Loveman E, et al. Surgery for weight loss in adults. Cochrane Database Syst Rev, CD003641. 2014;8
3.
go back to reference Park JY, Kim YJ. Successful laparoscopic reversal of gastric bypass in a patient with malnutrition. Ann Surg Treat Res. 2014;87(4):217–21.CrossRef Park JY, Kim YJ. Successful laparoscopic reversal of gastric bypass in a patient with malnutrition. Ann Surg Treat Res. 2014;87(4):217–21.CrossRef
4.
go back to reference Arman GA, Himpens J, Bolckmans R, et al. Medium-Term Outcomes after Reversal of Roux-en-Y Gastric Bypass. Obes Surg. 2018;28(3):781–90.CrossRef Arman GA, Himpens J, Bolckmans R, et al. Medium-Term Outcomes after Reversal of Roux-en-Y Gastric Bypass. Obes Surg. 2018;28(3):781–90.CrossRef
5.
go back to reference Ambrecht U, Lundell L, Lindstedt G, et al. Causes of malabsorption after total gastrectomy with Roux-en-Y reconstruction. Acta Chir Scand. 1988;154(1):37–41. Ambrecht U, Lundell L, Lindstedt G, et al. Causes of malabsorption after total gastrectomy with Roux-en-Y reconstruction. Acta Chir Scand. 1988;154(1):37–41.
6.
go back to reference Higa KD, Boone KB, Ho T. Complications of the laparoscopic Rouxen-Y gastric bypass: 1040 patients—what have we learned? Obes Surg. 2000;10(6):509–13.CrossRef Higa KD, Boone KB, Ho T. Complications of the laparoscopic Rouxen-Y gastric bypass: 1040 patients—what have we learned? Obes Surg. 2000;10(6):509–13.CrossRef
7.
go back to reference Himpens J, Dapri G, Cadière GB. Laparoscopic conversion of the gastric bypass into a normal anatomy. Obes Surg. 2006;16(7):908–12.CrossRef Himpens J, Dapri G, Cadière GB. Laparoscopic conversion of the gastric bypass into a normal anatomy. Obes Surg. 2006;16(7):908–12.CrossRef
8.
go back to reference Ma P, Reddy S, Lloyd A, et al. Reversal of roux-en-Y gastric bypass at a large tertiary center with a large experience in laparoscopic gastric bypass revision: Indications and outcomes. Surg Obes Relat Dis. 2016;12:S56–75. A5010, Posters of distinction Ma P, Reddy S, Lloyd A, et al. Reversal of roux-en-Y gastric bypass at a large tertiary center with a large experience in laparoscopic gastric bypass revision: Indications and outcomes. Surg Obes Relat Dis. 2016;12:S56–75. A5010, Posters of distinction
9.
go back to reference Vilallonga R, van de Vrande S, Himpens J. Laparoscopic reversal of Roux-en-Y gastric bypass into normal anatomy with or without sleeve gastrectomy. Surg Endosc. 2013;27(12):4640–8.CrossRef Vilallonga R, van de Vrande S, Himpens J. Laparoscopic reversal of Roux-en-Y gastric bypass into normal anatomy with or without sleeve gastrectomy. Surg Endosc. 2013;27(12):4640–8.CrossRef
10.
go back to reference Nergaard BJ, Leifsson BG, Hedenbro J, et al. Gastric bypass with long alimentary limb or long pancreato-biliary limb--long-term results on weight loss, resolution of co-morbidities and metabolic parameters. Obes Surg. 2014;24(10):1595–602.CrossRef Nergaard BJ, Leifsson BG, Hedenbro J, et al. Gastric bypass with long alimentary limb or long pancreato-biliary limb--long-term results on weight loss, resolution of co-morbidities and metabolic parameters. Obes Surg. 2014;24(10):1595–602.CrossRef
11.
go back to reference Pernar LI, Kim JJ, Shikora SA. Gastric bypass reversal: a 7-year experience. Surg Obes Relat Dis. 2016;12(8):1492–8.CrossRef Pernar LI, Kim JJ, Shikora SA. Gastric bypass reversal: a 7-year experience. Surg Obes Relat Dis. 2016;12(8):1492–8.CrossRef
12.
go back to reference Akusoba I, Birriel TJ, El Chaar M. Management of Excessive Weight Loss Following Laparoscopic Roux-en-Y Gastric Bypass: Clinical Algorithm and Surgical Techniques. Obes Surg. 2016;26(1):5–11.CrossRef Akusoba I, Birriel TJ, El Chaar M. Management of Excessive Weight Loss Following Laparoscopic Roux-en-Y Gastric Bypass: Clinical Algorithm and Surgical Techniques. Obes Surg. 2016;26(1):5–11.CrossRef
13.
go back to reference Ma P, Ghiassi S, Lloyd A, et al. Reversal of Roux en Y gastric bypass: largest single institution experience. Surg Obes Relat Dis. 2019;15(8):1311–6.CrossRef Ma P, Ghiassi S, Lloyd A, et al. Reversal of Roux en Y gastric bypass: largest single institution experience. Surg Obes Relat Dis. 2019;15(8):1311–6.CrossRef
14.
go back to reference Agrawal V, Wilfong JB, Rich CE, et al. Reversal of Gastric Bypass Resolves Hyperoxaluria and Improves Oxalate Nephropathy Secondary to Roux-en-Y Gastric Bypass. Case Rep Nephrol Dial. 2016;6(3):114–9.CrossRef Agrawal V, Wilfong JB, Rich CE, et al. Reversal of Gastric Bypass Resolves Hyperoxaluria and Improves Oxalate Nephropathy Secondary to Roux-en-Y Gastric Bypass. Case Rep Nephrol Dial. 2016;6(3):114–9.CrossRef
15.
go back to reference Campos GM, Ziemelis M, Paparodis R, et al. Laparoscopic reversal of Roux-en-Y gastric bypass: technique and utility for treatment of endocrine complications. Surg Obes Relat Dis. 2014;10(1):36–43.CrossRef Campos GM, Ziemelis M, Paparodis R, et al. Laparoscopic reversal of Roux-en-Y gastric bypass: technique and utility for treatment of endocrine complications. Surg Obes Relat Dis. 2014;10(1):36–43.CrossRef
16.
go back to reference Zaveri H, Dallal RM, Cottam D, et al. Indications and Operative Outcomes of Gastric Bypass Reversal. Obes Surg. 2016;26(10):2285–90.CrossRef Zaveri H, Dallal RM, Cottam D, et al. Indications and Operative Outcomes of Gastric Bypass Reversal. Obes Surg. 2016;26(10):2285–90.CrossRef
17.
go back to reference Dapri G, Cadière GB, Himpens J. Laparoscopic reconversion of Roux-en-Y gastric bypass to original anatomy -technique and preliminary outcomes. Obes Surg. 2011;21(8):1289–95.CrossRef Dapri G, Cadière GB, Himpens J. Laparoscopic reconversion of Roux-en-Y gastric bypass to original anatomy -technique and preliminary outcomes. Obes Surg. 2011;21(8):1289–95.CrossRef
18.
go back to reference Akusoba I, El Chaar M. Laparoscopic Roux-en-Y gastric bypass reversal. Surg Obes Relat Dis. 2016;12(2):441–2.CrossRef Akusoba I, El Chaar M. Laparoscopic Roux-en-Y gastric bypass reversal. Surg Obes Relat Dis. 2016;12(2):441–2.CrossRef
19.
go back to reference Qvigstad E, Gulseth HL, Risstad H, et al. A novel technique of Roux-en-Y gastric bypass reversal for postprandial hyperinsulinemic hypoglycaemia: A case report. Int J Surg Case Rep. 2016;21:91–4.CrossRef Qvigstad E, Gulseth HL, Risstad H, et al. A novel technique of Roux-en-Y gastric bypass reversal for postprandial hyperinsulinemic hypoglycaemia: A case report. Int J Surg Case Rep. 2016;21:91–4.CrossRef
20.
go back to reference Shah K, Nergård BJ, Fagerland MW, et al. Distal gastric bypass: 2-m biliopancreatic limb construction with varying lengths of common channel. Surg Obes Relat Dis. 2019;15(9):1520–6.CrossRef Shah K, Nergård BJ, Fagerland MW, et al. Distal gastric bypass: 2-m biliopancreatic limb construction with varying lengths of common channel. Surg Obes Relat Dis. 2019;15(9):1520–6.CrossRef
21.
go back to reference Shah K, Nergård BJ, Fagerland MW, et al. Limb Length in Gastric Bypass in Super-Obese Patients-Importance of Length of Total Alimentary Small Bowel Tract. Obes Surg. 2019;29(7):2012–21.CrossRef Shah K, Nergård BJ, Fagerland MW, et al. Limb Length in Gastric Bypass in Super-Obese Patients-Importance of Length of Total Alimentary Small Bowel Tract. Obes Surg. 2019;29(7):2012–21.CrossRef
22.
go back to reference Shoar S. Nguyen T2, Ona MA3, et al. Roux-en-Y gastric bypass reversal: a systematic review. Surg Obes Relat Dis. 2016;12(7):1366–72.CrossRef Shoar S. Nguyen T2, Ona MA3, et al. Roux-en-Y gastric bypass reversal: a systematic review. Surg Obes Relat Dis. 2016;12(7):1366–72.CrossRef
23.
go back to reference Pucher PH, Lord AC, Sodergren MH, et al. Reversal to normal anatomy after failed gastric bypass: systematic review of indications, techniques, and outcomes. Surg Obes Relat Dis. 2016;12(7):1351–6.CrossRef Pucher PH, Lord AC, Sodergren MH, et al. Reversal to normal anatomy after failed gastric bypass: systematic review of indications, techniques, and outcomes. Surg Obes Relat Dis. 2016;12(7):1351–6.CrossRef
24.
go back to reference Alizadeh RF, Li S, Inaba C, et al. Risk Factors for Gastrointestinal Leak after Bariatric Surgery: MBASQIP Analysis. J Am Coll Surg. 2018;227(1):135–41.CrossRef Alizadeh RF, Li S, Inaba C, et al. Risk Factors for Gastrointestinal Leak after Bariatric Surgery: MBASQIP Analysis. J Am Coll Surg. 2018;227(1):135–41.CrossRef
Metadata
Title
Roux-en-Y Gastric Bypass Reversal: A Novel Technique With Functional Reversal – Case Series
Authors
Kamran Shah
Hjörtur Gislason
Publication date
01-04-2020
Publisher
Springer US
Published in
Obesity Surgery / Issue 4/2020
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-020-04420-8

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