Skip to main content
Top
Published in: Obesity Surgery 5/2019

01-05-2019 | Sleeve Gastrectomy | Original Contributions

Weight Regain After Bariatric Surgery—A Multicentre Study of 9617 Patients from Indian Bariatric Surgery Outcome Reporting Group

Authors: Sarfaraz J. Baig, Pallawi Priya, Kamal K. Mahawar, Sumeet Shah, for the Indian Bariatric Surgery Outcome Reporting (IBSOR) Group

Published in: Obesity Surgery | Issue 5/2019

Login to get access

Abstract

Background

There is little robust data on weight regain (WR) after bariatric surgery making it difficult to counsel patients regarding long-term outcomes of different bariatric procedures. The purpose of this study was to see WR in medium and long term after SG, RYGB, and OAGB in Indian population.

Methods

In a multicentre study, data on preoperative and postoperative weights over 5 years were collected. Multiple definitions were applied to find the proportion of patients with significant WR increase of 25% of lost weight from nadir (definition 1), weight gain of > 10 kg from nadir (definition 2), and BMI gain of > 5 kg/m2 from nadir (definition 3). The proportion of those with significant WR was compared across sub-groups.

Results

A total of 9617 patients were included. Median WR at 5 years was 14.1% of lost weight, 1.92 kg/m2, and 5 kg. Significant WR using definition 1 was 35.1%, 14.6%, and 3% after sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and mini-one anastomosis gastric bypass (OAGB) respectively. Severe albumin deficiency was highest in OAGB (5.9%) patients followed by SG (2.9%) and RYGB (2.2%) at 5 years(p = 0.023). Haemoglobin levels < 10 g/dL were seen in 8.2%, 9.0%, and 13.9% of SG, RYGB, and OAGB patients respectively (p = 0.041).

Conclusions

In the first comparative study of WR, OAGB had lesser WR in comparison to SG and RYGB but had the most impact on Hb and albumin levels in the long term. Definition selection for reporting WR has a significant impact on the results. There is a need for standardising the reporting of WR in bariatric literature.
Literature
1.
go back to reference Juodeikis Ž, Brimas G. Long-term results after sleeve gastrectomy: a systematic review. Surg Obes Relat Dis. 2017;13:693–9.CrossRefPubMed Juodeikis Ž, Brimas G. Long-term results after sleeve gastrectomy: a systematic review. Surg Obes Relat Dis. 2017;13:693–9.CrossRefPubMed
2.
go back to reference Shoar S, Saber AA. Long-term and midterm outcomes of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass: a systematic review and meta-analysis of comparative studies. Surg Obes Relat Dis. 2017;13:170–80.CrossRefPubMed Shoar S, Saber AA. Long-term and midterm outcomes of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass: a systematic review and meta-analysis of comparative studies. Surg Obes Relat Dis. 2017;13:170–80.CrossRefPubMed
3.
go back to reference Rutledge R, Walsh TR. Continued excellent results with the mini-gastric bypass: six-year study in 2,410 patients. Obes Surg. 2005;15:1304–8.CrossRefPubMed Rutledge R, Walsh TR. Continued excellent results with the mini-gastric bypass: six-year study in 2,410 patients. Obes Surg. 2005;15:1304–8.CrossRefPubMed
4.
go back to reference Bruzzi M, Rau C, Voron T, et al. Single anastomosis or mini-gastric bypass: long-term results and quality of life after a 5-year follow-up. Surg Obes Relat Dis. 2015;11:321–6.CrossRefPubMed Bruzzi M, Rau C, Voron T, et al. Single anastomosis or mini-gastric bypass: long-term results and quality of life after a 5-year follow-up. Surg Obes Relat Dis. 2015;11:321–6.CrossRefPubMed
5.
go back to reference Alkhalifah N, Lee W-J, Hai TC, et al. 15-year experience of laparoscopic single anastomosis (mini-)gastric bypass: comparison with other bariatric procedures. Surg Endosc. 2018;32:3024–31.CrossRefPubMed Alkhalifah N, Lee W-J, Hai TC, et al. 15-year experience of laparoscopic single anastomosis (mini-)gastric bypass: comparison with other bariatric procedures. Surg Endosc. 2018;32:3024–31.CrossRefPubMed
6.
go back to reference Kular KS, Manchanda N, Rutledge R. A 6-year experience with 1,054 mini-gastric bypasses—first study from Indian subcontinent. Obes Surg. 2014;24:1430–5.CrossRefPubMed Kular KS, Manchanda N, Rutledge R. A 6-year experience with 1,054 mini-gastric bypasses—first study from Indian subcontinent. Obes Surg. 2014;24:1430–5.CrossRefPubMed
7.
go back to reference Jammu GS, Sharma R. A 7-year clinical audit of 1107 cases comparing sleeve gastrectomy, Roux-en-Y gastric bypass, and mini-gastric bypass, to determine an effective and safe bariatric and metabolic procedure. Obes Surg. 2016;26(5):926–32 Jammu GS, Sharma R. A 7-year clinical audit of 1107 cases comparing sleeve gastrectomy, Roux-en-Y gastric bypass, and mini-gastric bypass, to determine an effective and safe bariatric and metabolic procedure. Obes Surg. 2016;26(5):926–32
8.
9.
go back to reference Parikh M, Eisenberg D, Johnson J, et al. American Society for Metabolic and Bariatric Surgery Clinical Issues Committee. American Society for Metabolic and Bariatric Surgery review of the literature on one-anastomosis gastric bypass. Surg Obes Relat Dis. 2018;14:1088–92.CrossRefPubMed Parikh M, Eisenberg D, Johnson J, et al. American Society for Metabolic and Bariatric Surgery Clinical Issues Committee. American Society for Metabolic and Bariatric Surgery review of the literature on one-anastomosis gastric bypass. Surg Obes Relat Dis. 2018;14:1088–92.CrossRefPubMed
10.
go back to reference Courcoulas AP, Christian NJ, Belle SH, et al. Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity. JAMA. 2013;310:2416–25.PubMedPubMedCentral Courcoulas AP, Christian NJ, Belle SH, et al. Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity. JAMA. 2013;310:2416–25.PubMedPubMedCentral
11.
go back to reference Mahawar KK, Graham Y, Carr WRJ, et al. Revisional Roux-en-Y gastric bypass and sleeve gastrectomy: a systematic review of comparative outcomes with respective primary procedures. Obes Surg. 2015;25:1271–80.CrossRefPubMed Mahawar KK, Graham Y, Carr WRJ, et al. Revisional Roux-en-Y gastric bypass and sleeve gastrectomy: a systematic review of comparative outcomes with respective primary procedures. Obes Surg. 2015;25:1271–80.CrossRefPubMed
12.
go back to reference Lauti M, Lemanu D, Zeng ISL, et al. Definition determines weight regain outcomes after sleeve gastrectomy. Surg Obes Relat Dis. 2017;13:1123–9.CrossRefPubMed Lauti M, Lemanu D, Zeng ISL, et al. Definition determines weight regain outcomes after sleeve gastrectomy. Surg Obes Relat Dis. 2017;13:1123–9.CrossRefPubMed
13.
go back to reference Bailly L, Schiavo L, Sebastianelli L, Fabre R, Pradier C, Iannelli A. Anemia and bariatric surgery: results of a national French survey on administrative data of 306,298 consecutive patients between 2008 and 2016. Obes Surg. 2018;28(8):2313–20 Bailly L, Schiavo L, Sebastianelli L, Fabre R, Pradier C, Iannelli A. Anemia and bariatric surgery: results of a national French survey on administrative data of 306,298 consecutive patients between 2008 and 2016. Obes Surg. 2018;28(8):2313–20
14.
go back to reference Karimi M, Kabir A, Nejatifar M, et al. Trend of changes in serum albumin and its relation with sex, age, and BMI following laparoscopic mini-gastric bypass surgery in morbid obese cases. Obes Surg. 2018;28:671–80.CrossRefPubMed Karimi M, Kabir A, Nejatifar M, et al. Trend of changes in serum albumin and its relation with sex, age, and BMI following laparoscopic mini-gastric bypass surgery in morbid obese cases. Obes Surg. 2018;28:671–80.CrossRefPubMed
15.
go back to reference Liu SY-W, Wong SK-H, Lam CC-H, et al. Long-term results on weight loss and diabetes remission after laparoscopic sleeve gastrectomy for a morbidly obese Chinese population. Obes Surg. 2015;25:1901–8.CrossRefPubMed Liu SY-W, Wong SK-H, Lam CC-H, et al. Long-term results on weight loss and diabetes remission after laparoscopic sleeve gastrectomy for a morbidly obese Chinese population. Obes Surg. 2015;25:1901–8.CrossRefPubMed
16.
go back to reference Abdallah E, El Nakeeb A, Yousef T, et al. Impact of extent of antral resection on surgical outcomes of sleeve gastrectomy for morbid obesity (a prospective randomized study). Obes Surg. 2014;24:1587–94.CrossRefPubMed Abdallah E, El Nakeeb A, Yousef T, et al. Impact of extent of antral resection on surgical outcomes of sleeve gastrectomy for morbid obesity (a prospective randomized study). Obes Surg. 2014;24:1587–94.CrossRefPubMed
17.
go back to reference Braghetto I, Csendes A, Lanzarini E, et al. Is laparoscopic sleeve gastrectomy an acceptable primary bariatric procedure in obese patients? early and 5-year postoperative results. Surg Laparosc Endosc Percutan Tech. 2012;22:479–86.CrossRefPubMed Braghetto I, Csendes A, Lanzarini E, et al. Is laparoscopic sleeve gastrectomy an acceptable primary bariatric procedure in obese patients? early and 5-year postoperative results. Surg Laparosc Endosc Percutan Tech. 2012;22:479–86.CrossRefPubMed
18.
go back to reference Casella G, Soricelli E, Giannotti D, et al. Long-term results after laparoscopic sleeve gastrectomy in a large monocentric series. Surg Obes Relat Dis. 2016;12:757–62.CrossRefPubMed Casella G, Soricelli E, Giannotti D, et al. Long-term results after laparoscopic sleeve gastrectomy in a large monocentric series. Surg Obes Relat Dis. 2016;12:757–62.CrossRefPubMed
19.
go back to reference Ritz P, Becouarn G, Douay O, et al. Gastric bypass is not associated with protein malnutrition in morbidly obese patients. Obes Surg. 2009;19:840–4.CrossRefPubMed Ritz P, Becouarn G, Douay O, et al. Gastric bypass is not associated with protein malnutrition in morbidly obese patients. Obes Surg. 2009;19:840–4.CrossRefPubMed
20.
go back to reference Obeidat F, Shanti H, Mismar A, et al. The magnitude of antral resection in laparoscopic sleeve gastrectomy and its relationship to excess weight loss. Obes Surg. 2015;25:1928–32.CrossRefPubMed Obeidat F, Shanti H, Mismar A, et al. The magnitude of antral resection in laparoscopic sleeve gastrectomy and its relationship to excess weight loss. Obes Surg. 2015;25:1928–32.CrossRefPubMed
21.
go back to reference Bohdjalian A, Langer FB, Shakeri-Leidenmühler S, et al. Sleeve gastrectomy as sole and definitive bariatric procedure: 5-year results for weight loss and ghrelin. Obes Surg. 2010;20:535–40.CrossRefPubMed Bohdjalian A, Langer FB, Shakeri-Leidenmühler S, et al. Sleeve gastrectomy as sole and definitive bariatric procedure: 5-year results for weight loss and ghrelin. Obes Surg. 2010;20:535–40.CrossRefPubMed
22.
go back to reference Brethauer SA, Aminian A, Romero-Talamás H, et al. Can diabetes be surgically cured? long-term metabolic effects of bariatric surgery in obese patients with type 2 diabetes mellitus. Ann Surg. 2013;258:1.CrossRef Brethauer SA, Aminian A, Romero-Talamás H, et al. Can diabetes be surgically cured? long-term metabolic effects of bariatric surgery in obese patients with type 2 diabetes mellitus. Ann Surg. 2013;258:1.CrossRef
23.
go back to reference Mahawar KK, Kular KS, Parmar C, et al. Perioperative practices concerning one anastomosis (mini) gastric bypass: a survey of 210 surgeons. Obes Surg. 2018;28:204–11.CrossRefPubMed Mahawar KK, Kular KS, Parmar C, et al. Perioperative practices concerning one anastomosis (mini) gastric bypass: a survey of 210 surgeons. Obes Surg. 2018;28:204–11.CrossRefPubMed
24.
go back to reference Young MT, Phelan MJ, Nguyen NT. A decade analysis of trends and outcomes of male vs female patients who underwent bariatric surgery. J Am Coll Surg. 2016;222:226–31.CrossRefPubMed Young MT, Phelan MJ, Nguyen NT. A decade analysis of trends and outcomes of male vs female patients who underwent bariatric surgery. J Am Coll Surg. 2016;222:226–31.CrossRefPubMed
25.
go back to reference Zhang Y, Zhao H, Cao Z, et al. A randomized clinical trial of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy for the treatment of morbid obesity in China: a 5-year outcome. Obes Surg. 2014;24:1617–24.CrossRefPubMed Zhang Y, Zhao H, Cao Z, et al. A randomized clinical trial of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy for the treatment of morbid obesity in China: a 5-year outcome. Obes Surg. 2014;24:1617–24.CrossRefPubMed
26.
go back to reference Salminen P, Helmiö M, Ovaska J, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity. JAMA. 2018;319:241.CrossRefPubMedPubMedCentral Salminen P, Helmiö M, Ovaska J, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss at 5 years among patients with morbid obesity. JAMA. 2018;319:241.CrossRefPubMedPubMedCentral
27.
go back to reference Alkhalifah N, Lee W-J, Hai TC, Ser K-H, Chen J-C, Wu C-C. 15-year experience of laparoscopic single anastomosis (mini-)gastric bypass: comparison with other bariatric procedures. Surg Endosc. 2018;32(7):3024–31 Alkhalifah N, Lee W-J, Hai TC, Ser K-H, Chen J-C, Wu C-C. 15-year experience of laparoscopic single anastomosis (mini-)gastric bypass: comparison with other bariatric procedures. Surg Endosc. 2018;32(7):3024–31
28.
go back to reference Peterli R, Steinert RE, Woelnerhanssen B, et al. Metabolic and hormonal changes after laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy: a randomized, Prospective Trial. Obes Surg. 2012;22:740–8.CrossRefPubMedPubMedCentral Peterli R, Steinert RE, Woelnerhanssen B, et al. Metabolic and hormonal changes after laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy: a randomized, Prospective Trial. Obes Surg. 2012;22:740–8.CrossRefPubMedPubMedCentral
29.
go back to reference Braghetto I, Cortes C, Herquiñigo D, et al. Evaluation of the radiological gastric capacity and evolution of the BMI 2-3 years after sleeve gastrectomy. Obes Surg. 2009;19:1262–9.CrossRefPubMed Braghetto I, Cortes C, Herquiñigo D, et al. Evaluation of the radiological gastric capacity and evolution of the BMI 2-3 years after sleeve gastrectomy. Obes Surg. 2009;19:1262–9.CrossRefPubMed
30.
go back to reference Lauti M, Kularatna M, Hill AG, et al. Weight regain following sleeve gastrectomy—a systematic review. Obes Surg. 2016;26:1326–34.CrossRefPubMed Lauti M, Kularatna M, Hill AG, et al. Weight regain following sleeve gastrectomy—a systematic review. Obes Surg. 2016;26:1326–34.CrossRefPubMed
31.
go back to reference Cooper TC, Simmons EB, Webb K, et al. Trends in weight regain following Roux-en-Y gastric bypass (RYGB) bariatric surgery. Obes Surg. 2015;25:1474–81.CrossRefPubMed Cooper TC, Simmons EB, Webb K, et al. Trends in weight regain following Roux-en-Y gastric bypass (RYGB) bariatric surgery. Obes Surg. 2015;25:1474–81.CrossRefPubMed
32.
go back to reference Mechanick JI, Youdim A, Jones DB, et al. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient-2013 update: cosponsored by American Association Of Clinical Endocrinologists, The Obesity Society, And American Society Fo. Obesity. 2013;21:S1–27.CrossRefPubMed Mechanick JI, Youdim A, Jones DB, et al. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient-2013 update: cosponsored by American Association Of Clinical Endocrinologists, The Obesity Society, And American Society Fo. Obesity. 2013;21:S1–27.CrossRefPubMed
33.
go back to reference Mahawar K, Parmar C, Carr WJ, et al. Impact of biliopancreatic limb length on severe protein–calorie malnutrition requiring revisional surgery after one anastomosis (mini) gastric bypass. J Minim Access Surg. 2018;14:37.CrossRefPubMedPubMedCentral Mahawar K, Parmar C, Carr WJ, et al. Impact of biliopancreatic limb length on severe protein–calorie malnutrition requiring revisional surgery after one anastomosis (mini) gastric bypass. J Minim Access Surg. 2018;14:37.CrossRefPubMedPubMedCentral
34.
go back to reference King WC, Hinerman AS, Belle SH, et al. Comparison of the performance of common measures of weight regain after bariatric surgery for association with clinical outcomes. JAMA. 2018;320:1560.CrossRefPubMedPubMedCentral King WC, Hinerman AS, Belle SH, et al. Comparison of the performance of common measures of weight regain after bariatric surgery for association with clinical outcomes. JAMA. 2018;320:1560.CrossRefPubMedPubMedCentral
36.
go back to reference Blencowe NS, Brown JM, Cook JA, et al. Interventions in randomised controlled trials in surgery: issues to consider during trial design. Trials. 2015;16:392.CrossRefPubMedPubMedCentral Blencowe NS, Brown JM, Cook JA, et al. Interventions in randomised controlled trials in surgery: issues to consider during trial design. Trials. 2015;16:392.CrossRefPubMedPubMedCentral
Metadata
Title
Weight Regain After Bariatric Surgery—A Multicentre Study of 9617 Patients from Indian Bariatric Surgery Outcome Reporting Group
Authors
Sarfaraz J. Baig
Pallawi Priya
Kamal K. Mahawar
Sumeet Shah
for the Indian Bariatric Surgery Outcome Reporting (IBSOR) Group
Publication date
01-05-2019
Publisher
Springer US
Published in
Obesity Surgery / Issue 5/2019
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-019-03734-6

Other articles of this Issue 5/2019

Obesity Surgery 5/2019 Go to the issue