Top

Obesity Surgery

Published in:

01-01-2019 | Original Contributions

The Relationship Between Histopathologic Findings and Body Mass Index in Sleeve Gastrectomy Materials

Authors: Yasemen Adalı, Kenan Binnetoğlu, Hüseyin Avni Eroğlu, Nilhan Kaya, Gülname Fındık Güvendi

Published in: Obesity Surgery | Issue 1/2019

Abstract

Objective

For treatment of obesity, which is one of the important health problems of the present time, lifestyle modification, pharmacotherapy, behavioral treatment methods, and surgical procedures are commonly used. Sleeve gastrectomy is widely used among surgical procedures. We aimed to investigate the relationship between histopathologic findings and body mass indices (BMIs) of cases with sleeve gastrectomy in our study.

Methods

Thirty-seven patients were included in our study who underwent sleeve gastrectomy and whose operation materials were examined histopathologically in our hospital. Two pathologists re-evaluated all gastrectomy materials. The relationship between BMI and the presence of gastritis, atrophy, intestinal metaplasia (IM), Helicobacter pylori (HPL), and other histopathological findings was investigated.

Results

The mean age of patients included in the study was 34.7 + 9.3 years. Of patients, 70.3% were female and 29.7% were male. There was a statistically significant difference between BMI and IM among the evaluated histopathologic parameters. Moreover, IM was significantly more present in patients with type 2 diabetes.

Conclusions

There is no previous study investigating the relationship between gastric histopathological findings and BMI in sleeve gastrectomy patients. We think that the statistically significant difference between BMI and IM that we found in our study may shed light on studies to be performed in the future.

Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity among US adults, 1999-2000. JAMA. 2002;288(14):1723–7.CrossRef

Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA. 2006;295(13):1549–55.CrossRef

Villarejo C, Fernández-Aranda F, Jiménez-Murcia S, et al. Lifetime obesity in patients with eating disorders: increasing prevalence, clinical and personality correlates. Eur Eat Disord Rev. 2012;20(3):250–4. https://doi.org/10.1002/erv.2166.CrossRefPubMedPubMedCentral

Bozbora A. Morbid Obezite. Güncel Cerrahi Tedavi, Çev. Edi. Ergüney S, Çiçek Y, Avrupa Tıp Kitapçılık, İstanbul, 6.Baskı 2001:105–109.

World Health Organization. Global health risks: mortality and burden of disease attributable to selected major risks. Geneva: World Health Organization; 2009.

Schirmer B, Schauer PR. The surgical management of obesity. In: Brunicardi F, Andersen D, Hunter J, et al., editors. Schwartz’s principles of surgery in the dition. USA: McGraw-Hill Companies; 2010. p. 952–3.

Vardar E, Öztürk AM, Ersöz D, et al. Routine careful histopathological examination should be performed in sleeve gastrectomy specimens. J HealthSciences. 2017;7(1):44–9.

Safaan T, Bashah M, El Ansari W, et al. Histopathological changes in laparoscopic sleeve gastrectomy specimens: prevalence, risk factors, and value of routine histopathologic examination. Obes Surg. 2017 Jul;27(7):1741–9. https://doi.org/10.1007/s11695-016-2525-1.CrossRefPubMedPubMedCentral

Onzi TR, d’Acampora AJ, de Araújo FM, et al. Gastric histopathology in laparoscopic sleeve gastrectomy: pre- and post-operative comparison. Obes Surg. 2014;24(3):371–6. https://doi.org/10.1007/s11695-013-1107-8.CrossRefPubMed

10.

Vrabie CD, Cojocaru M, Waller M, et al. The main histopathological gastric lesions in obese patients who underwent sleeve gastrectomy. Dicle Tıp Dergisi / Dicle Medical Journal Cilt. 2010;37(2):97–103. 9

11.

Kinsinger LA, Garber JC, Whipple O. A review of sleeve gastrectomy specimen histopathology. Am Surg. 2016;82(11):1101–4.PubMed

12.

Lauti M, Gormack SE, Thomas JM, et al. What does the excised stomach from sleeve gastrectomy tell us? Obes Surg. 2016;26(4):839–42. https://doi.org/10.1007/s11695-015-1832-2.11.CrossRefPubMed

13.

Almazeedi S, Al-Sabah S, Al-Mulla A, et al. Gastric histopathologies in patients undergoing laparoscopic sleeve gastrectomies. Obes Surg. 2013;23(3):314–9. https://doi.org/10.1007/s11695-012-0821-y.CrossRefPubMed

14.

Rath-Wolfson L, Varona R, Bubis G, et al. Gastritis in patients undergoing sleeve gastrectomy: prevalence, ethnic distribution, and impact on glycemic. Medicine (Baltimore). 2017;96(16):e6602. https://doi.org/10.1097/MD.0000000000006602.CrossRef

15.

Obeidat FW, Shahait AD, Shanti HA, et al. Histopathology results of Jordanian patients after laparoscopic sleeve gastrectomy. Saudi J Obesity. 2015;3:18–20.CrossRef

16.

Makki AM, Aldaqal SM, Alorabi SH, et al. Chronic gastritis in morbidly obese patients with sleeve gastrectomy. Electron Physician. 2016;8(1):1786–90. https://doi.org/10.19082/1786.CrossRefPubMedPubMedCentral

17.

Muruzábal FJ, Frühbeck G, Gómez-Ambrosi J, et al. Immunocytochemical detection of leptin in non-mammalian vertebrate stomach. Gen Comp Endocrinol. 2002;128(2):149–52.CrossRefPubMed

18.

Frühbeck G, Gómez-Ambrosi J. Rationale for the existence of additional adipostatic hormones. FASEB J. 2001;15(11):1996–2006.CrossRefPubMed

19.

Moreno-Navarrete JM, Ortega F, Serino M, et al. Circulating lipopolysaccharide-binding protein (LBP) as a marker of obesity-related insulin resistance. Int J Obes. 2012;36(11):1442–9. https://doi.org/10.1038/ijo.2011.256.CrossRef

20.

Frühbeck G. Bariatric and metabolic surgery: a shift in eligibility and success criteria. Nat Rev Endocrinol. 2015;11(8):465–77. https://doi.org/10.1038/nrendo.2015.84. Epub 2015 Jun 9CrossRefPubMed

21.

Martín M, Burrell MA, Gómez-Ambrosi J, et al. Short- and long-term changes in gastric morphology and histopathology following sleeve gastrectomy in diet-induced obese rats. Obes Surg. 2012;22(4):634–40. https://doi.org/10.1007/s11695-012-0606-3.CrossRefPubMed

Title: The Relationship Between Histopathologic Findings and Body Mass Index in Sleeve Gastrectomy Materials
Authors: Yasemen Adalı
Kenan Binnetoğlu
Hüseyin Avni Eroğlu
Nilhan Kaya
Gülname Fındık Güvendi
Publication date: 01-01-2019
Publisher: Springer US
Published in: Obesity Surgery / Issue 1/2019
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-018-3518-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

The Relationship Between Histopathologic Findings and Body Mass Index in Sleeve Gastrectomy Materials

Abstract

Objective

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 1/2019

Gastric Bypass as a Third Bariatric Procedure—Our Experience with 42 Cases

Comparative Effectiveness of Different Bariatric Procedures in Super Morbid Obesity

Type 2 Diabetes Remission and Control in Overweight and in Mildly Obese Diabetic Patients at Long-Term Follow-Up After Biliopancreatic Diversion

Anastomotic Strictures After Roux-en-Y Gastric Bypass: a Cohort Study from the Scandinavian Obesity Surgery Registry

Examination of the Effectiveness of a Brief, Adapted Dialectical Behavior Therapy-Skills Training Group for Bariatric Surgical Candidates

Effects of Cognitive Behavioral Therapy on Eating Behaviors, Affective Symptoms, and Weight Loss After Bariatric Surgery: a Randomized Clinical Trial