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Obesity Surgery
Published in: Obesity Surgery 5/2017

01-05-2017 | Original Contributions

Investigating Factors Involved in Post Laparoscopic Sleeve Gastrectomy (LSG) Neuropathy

Authors: Almaha Alsabah, Salman Al Sabah, Suleiman Al-Sabah, Ahmad Al-Serri, Eliana Al Haddad, Waleed M. Renno

Published in: Obesity Surgery | Issue 5/2017

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Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) has gained popularity as the leading bariatric procedure for the treatment of morbid obesity. Due to the rising numbers of bariatric surgeries, neurologic complications have become increasingly recognized. Our aim was to examine biochemical and hormonal factors that are associated with neuropathy post-LSG.

Methods

Thirty-two patients were included: 16 patients with neuropathy in the neuropathic group (NG) and 16 patients without neuropathy in the control group (CG). Diagnosis was made by a consultant neurologist, and blood samples were taken to examine vitamin deficiencies and hormones involved in neuropathy.

Results

There was no significant difference between the BMI (p = 0.1) in both groups as well as excess weight loss percentages post-LSG at 12 months (p = 0.6). B12 levels were within normal range, but higher in NG (p = 0.005). Vitamin B1 and B2 levels were significantly lower in NG; p values are 0.000 and 0.031, respectively. Vitamin B6 levels were significantly higher in NG (p = 0.02) and copper levels were lower in NG (p = 0.009). There was no significant difference in GLP-1 response in both groups.

Conclusion

Our data showed post-LSG neuropathy is associated with lower levels of vitamin B1, B2, and copper, plus patients who are older in age. Vitamin B6 was significantly higher in the NG, which is, at toxic levels, associated with neuropathy. No difference in preoperative BMI, excess weight loss percent at 1 year, and GLP-1 levels was found. Larger data is required to validate our results.
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Metadata
Title
Investigating Factors Involved in Post Laparoscopic Sleeve Gastrectomy (LSG) Neuropathy
Authors
Almaha Alsabah
Salman Al Sabah
Suleiman Al-Sabah
Ahmad Al-Serri
Eliana Al Haddad
Waleed M. Renno
Publication date
01-05-2017
Publisher
Springer US
Published in
Obesity Surgery / Issue 5/2017
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-016-2466-8

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