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Obesity Surgery
Published in: Obesity Surgery 5/2016

01-05-2016 | Original Contributions

Predictive Factors for Insufficient Weight Loss After Bariatric Surgery: Does Obstructive Sleep Apnea Influence Weight Loss?

Authors: Christel A. L. de Raaff, Usha K. Coblijn, Nico de Vries, Martijn W. Heymans, Bob T. J. van den Berg, Willem F. van Tets, Bart A. van Wagensveld

Published in: Obesity Surgery | Issue 5/2016

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Abstract

Background

Important endpoints of bariatric surgery are weight loss and improvement of comorbidities, of which obstructive sleep apnea (OSA) is the highest accompanying comorbidity (70 %). This study aimed to evaluate the influence of OSA on weight loss after bariatric surgery and to provide predictive factors for insufficient weight loss (defined as ≤50 % excess weight loss (EWL)) at 1 year follow-up.

Methods

All consecutive patients, who underwent primary laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy between 2006 and 2014 were retrospectively reviewed. Patients with data on preoperative apnea-hypopnea index (AHI) and pre- and postoperative body mass index (BMI) were included. After surgery, the percentage excess weight loss (%EWL) and BMI changes were compared between preoperatively diagnosed OSA-, subdivided in mild, moderate, and severe OSA, and non-OSA patients. Multivariable logistic regression analysis evaluated predictive factors for ≤50 % EWL.

Results

A total of 816 patients, 522 (64 %) with and 294 (36 %) without OSA, were included. After 1 year, OSA patients achieved less %EWL than non-OSA patients (65.5 SD 20.7 versus 70.3 SD 21.0; p < 0.01). The lowest %EWL was seen in severe OSA patients (61.7 SD 20.2). However, when adjusted for waist circumference, BMI, and age, no effect of OSA was seen on %EWL or changes in BMI. Although AHI, gender, age, BMI, type of surgery, and type II diabetes were predictive factors for ≤50 % EWL (area under the curve 0.778), the AHI as variable was of little importance.

Conclusions

The presence of OSA does not individually impair weight loss after bariatric surgery.
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Metadata
Title
Predictive Factors for Insufficient Weight Loss After Bariatric Surgery: Does Obstructive Sleep Apnea Influence Weight Loss?
Authors
Christel A. L. de Raaff
Usha K. Coblijn
Nico de Vries
Martijn W. Heymans
Bob T. J. van den Berg
Willem F. van Tets
Bart A. van Wagensveld
Publication date
01-05-2016
Publisher
Springer US
Published in
Obesity Surgery / Issue 5/2016
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-1830-4

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