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Obesity Surgery
Published in: Obesity Surgery 12/2010

01-12-2010 | Clinical Research

Predictive Factors of Weight Loss 1 Year after Laparoscopic Gastric Bypass in Obese Patients

Authors: Muriel Coupaye, Jean Marc Sabaté, Benjamin Castel, Pauline Jouet, Christine Clérici, Simon Msika, Séverine Ledoux

Published in: Obesity Surgery | Issue 12/2010

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Abstract

Background

Substantial weight loss is achieved in majority of severely obese subjects undergoing laparoscopic gastric bypass (LGBP) but some fail to obtain expected results. Our aim was to identify preoperative factors that could influence weight loss (WL) 1 year after LGBP.

Methods

We studied the predictive value of clinical, biological, and dietary preoperative factors on weight loss in obese patients referred for LGBP. WL was assessed according to mean absolute weight loss (AWL) and mean percent excess weight loss (%EWL) 1 year after LGBP.

Results

One hundred twenty-three subjects were included (112 women, age 42 ± 10 years; weight 127 ± 23 kg; BMI 47 ± 8 kg/m2). Mean AWL was 39.4 ± 10.5 kg at 1 year, corresponding to a mean %EWL of 70.5 ± 21.2%. AWL was positively correlated with initial weight, BMI, and energy intake and negatively with age, female sex, and treatment for hypertension and diabetes. %EWL was negatively correlated with initial weight, BMI, and positively correlated with triglycerides and ferritinemia. In multivariate analysis, %EWL was negatively correlated only with initial BMI (p < 0.001). AWL was positively correlated with initial BMI and male sex (both p < 0.001), and negatively correlated with protein intake (p = 0.039) and treatment for diabetes (p = 0.021), but not with biomarkers of diabetes and insulin resistance.

Conclusion

Initial BMI appears to be a strong determinant of individual WL, but predictive factors differ when WL was expressed as %EWL or AWL. The treatment of diabetes rather than diabetes itself appears to affect WL.
Appendix
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Metadata
Title
Predictive Factors of Weight Loss 1 Year after Laparoscopic Gastric Bypass in Obese Patients
Authors
Muriel Coupaye
Jean Marc Sabaté
Benjamin Castel
Pauline Jouet
Christine Clérici
Simon Msika
Séverine Ledoux
Publication date
01-12-2010
Publisher
Springer-Verlag
Published in
Obesity Surgery / Issue 12/2010
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-010-0159-2

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