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Published in: Obesity Surgery 6/2015

01-06-2015 | Original Contributions

One Thousand Single Anastomosis (Omega Loop) Gastric Bypasses to Treat Morbid Obesity in a 7-Year Period: Outcomes Show Few Complications and Good Efficacy

Authors: Jean Marc Chevallier, Gustavo A. Arman, Martino Guenzi, Cedric Rau, Mathieu Bruzzi, Nathan Beaupel, Frank Zinzindohoué, Anne Berger

Published in: Obesity Surgery | Issue 6/2015

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Abstract

Background

A short-term randomized controlled trial shows that the one anastomosis gastric bypass (OAGB) is a safe and effective alternative to the Roux-en-Y gastric bypass (RYGB).

Objective

The aim of this study is to evaluate the OAGB at our University Hospital between 2006 and 2013.

Patients

One thousand patients have undergone an OAGB. Data were collected on all consecutive patients. The mean follow-up period was 31 months (SD, 26.3; range, 12–82.9), and complete follow-up was available in 126 of 175 patients (72 %) at 5 years after surgery.

Results

Mortality rate was 0.2 %. Overall morbidity was 5.5 %; 34 required reoperations: i.e., 6 leaks, 5 obstructions, 5 incisional hernias, 7 biliary refluxes, 2 perforated ulcers, 2 bleeds, 2 abscesses, and 1 anastomotic stricture. Four patients were reoperated for weight regain. Overall rate of marginal ulcers was 2 % (n = 20), all in heavy smokers. Conversion from an OAGB to a RYGB was required in nine cases (0.9 %): seven for intractable biliary reflux, two for a marginal ulcer. At 5 years, percent excess body mass index loss was 71.6 ± 27 %. One hundred patients with type-2 diabetes, with a mean preoperative HbA1C of 7.7 ± 1.9 %, were followed for >2 years; the total resolution rate was 85.7 %.

Conclusion

This study confirms that the OAGB is an effective procedure for morbid obesity with comparable outcomes to RYGB; in addition, it seems to be safer with lower morbidity. Its technical simplicity represents a real advantage and makes it an option that should be considered by all bariatric surgeons.
Literature
1.
go back to reference Sjostrom L, Narbro K, Sjostrom D, et al. Effect of bariatric surgery on mortality in Swedish obese subjects. NEJM. 2007;357:741–52.CrossRefPubMed Sjostrom L, Narbro K, Sjostrom D, et al. Effect of bariatric surgery on mortality in Swedish obese subjects. NEJM. 2007;357:741–52.CrossRefPubMed
2.
go back to reference Balsiger BM, Poggio JL, Kelly KA, et al. Ten and more years after vertical banded gastroplasty as primary operation for morbid obesity. J Gastrointest Surg. 2000;4:598–605.CrossRefPubMed Balsiger BM, Poggio JL, Kelly KA, et al. Ten and more years after vertical banded gastroplasty as primary operation for morbid obesity. J Gastrointest Surg. 2000;4:598–605.CrossRefPubMed
3.
go back to reference Chevallier JM, Païta M, Rodde-Dunet MH, et al. Predictive factors of outcome after gastric banding: a nationwide survey on the role of center activity and patient’s behavior. Ann Surg. 2007;246:1034–9.CrossRefPubMed Chevallier JM, Païta M, Rodde-Dunet MH, et al. Predictive factors of outcome after gastric banding: a nationwide survey on the role of center activity and patient’s behavior. Ann Surg. 2007;246:1034–9.CrossRefPubMed
4.
go back to reference Lönroth H, Dalenbäck J, Hagling E, et al. Laparoscopic gastric bypass. Surg Endosc. 1998;10:636–8.CrossRef Lönroth H, Dalenbäck J, Hagling E, et al. Laparoscopic gastric bypass. Surg Endosc. 1998;10:636–8.CrossRef
5.
6.
go back to reference Fisher BL, Buchwald H, Clark W, et al. Mini-gastric bypass controversy. Obes Surg. 2001;11:773–7.CrossRefPubMed Fisher BL, Buchwald H, Clark W, et al. Mini-gastric bypass controversy. Obes Surg. 2001;11:773–7.CrossRefPubMed
7.
go back to reference Carbajo M, Garcia-Caballero M, Toledano M, et al. One-anastomosis gastric bypass by laparoscopy: results of the first 209 patients. Obes Surg. 2005;15(3):398–404.CrossRefPubMed Carbajo M, Garcia-Caballero M, Toledano M, et al. One-anastomosis gastric bypass by laparoscopy: results of the first 209 patients. Obes Surg. 2005;15(3):398–404.CrossRefPubMed
8.
go back to reference Noun R, Skaff J, Riachi E, et al. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Obes Surg. 2012;22(5):697–703.CrossRefPubMed Noun R, Skaff J, Riachi E, et al. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Obes Surg. 2012;22(5):697–703.CrossRefPubMed
9.
go back to reference Lee WJ, Ser KH, Lee YC, et al. Laparoscopic Roux-en-Y vs. mini-gastric bypass for the treatment of morbid obesity: a 10-year experience. Obes Surg. 2012;22(12):1827–34.CrossRefPubMed Lee WJ, Ser KH, Lee YC, et al. Laparoscopic Roux-en-Y vs. mini-gastric bypass for the treatment of morbid obesity: a 10-year experience. Obes Surg. 2012;22(12):1827–34.CrossRefPubMed
10.
go back to reference Musella M, Susa A, Greco F, et al. The laparoscopic mini-gastric bypass: the Italian experience: outcomes from 974 consecutive cases in a multicenter review. Surg Endosc. 2014;28(1):156–63.CrossRefPubMed Musella M, Susa A, Greco F, et al. The laparoscopic mini-gastric bypass: the Italian experience: outcomes from 974 consecutive cases in a multicenter review. Surg Endosc. 2014;28(1):156–63.CrossRefPubMed
11.
go back to reference Kular KS, Manchanda N, Rutledge R. A 6-year experience with 1,054 mini-gastric bypasses- first study from Indian subcontinent. Obes Surg. 2014;24:1430–5.CrossRefPubMed Kular KS, Manchanda N, Rutledge R. A 6-year experience with 1,054 mini-gastric bypasses- first study from Indian subcontinent. Obes Surg. 2014;24:1430–5.CrossRefPubMed
12.
go back to reference Chevallier JM, Zinzindohoué F, Douard R, et al. Complications after laparoscopic adjustable gastric banding for morbid obesity: experience with 1000 patients over 7 years. Obes Surg. 2004;14:407–14. Chevallier JM, Zinzindohoué F, Douard R, et al. Complications after laparoscopic adjustable gastric banding for morbid obesity: experience with 1000 patients over 7 years. Obes Surg. 2004;14:407–14.
13.
go back to reference Chakhtoura G, Zinzindohoué F, Ghanem Y, et al. Chevallier JM primary results of laparoscopic mini-gastric bypass in a French obesity-surgery specialized university hospital. Obes Surg. 2008;18:1130–3.CrossRefPubMed Chakhtoura G, Zinzindohoué F, Ghanem Y, et al. Chevallier JM primary results of laparoscopic mini-gastric bypass in a French obesity-surgery specialized university hospital. Obes Surg. 2008;18:1130–3.CrossRefPubMed
14.
15.
go back to reference Clavien PA, Barkun J, de Oliveira ML, et al. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250:187–96.CrossRefPubMed Clavien PA, Barkun J, de Oliveira ML, et al. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250:187–96.CrossRefPubMed
16.
go back to reference Rutledge R. The mini-gastric bypass: experience with the first 1,274 cases. Obes Surg. 2001;11:276–80.CrossRefPubMed Rutledge R. The mini-gastric bypass: experience with the first 1,274 cases. Obes Surg. 2001;11:276–80.CrossRefPubMed
18.
go back to reference Schauer P, Ikramuddin S, Hamad G, et al. The learning curve for laparoscopic Roux-en-Y gastric bypass is 100 cases. Surg Endosc. 2003;17(2):212–5.CrossRefPubMed Schauer P, Ikramuddin S, Hamad G, et al. The learning curve for laparoscopic Roux-en-Y gastric bypass is 100 cases. Surg Endosc. 2003;17(2):212–5.CrossRefPubMed
19.
go back to reference Su-Hsin C, Stoll C, Jihyun S, et al. The effectiveness and risks of bariatric surgery, an updates systematic review and meta-analysis. JAMA Surg. 2014;149(3):275–87.CrossRef Su-Hsin C, Stoll C, Jihyun S, et al. The effectiveness and risks of bariatric surgery, an updates systematic review and meta-analysis. JAMA Surg. 2014;149(3):275–87.CrossRef
20.
go back to reference Hwang RF, Swartz DE, Felix EL. Causes of small bowel obstruction after laparoscopic gastric bypass. Surg Endosc. 2004;18(11):1631–5.CrossRefPubMed Hwang RF, Swartz DE, Felix EL. Causes of small bowel obstruction after laparoscopic gastric bypass. Surg Endosc. 2004;18(11):1631–5.CrossRefPubMed
21.
go back to reference Jacobsen HJ, Nergard BJ, Leifsson BG, et al. Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-Y gastric bypass. Br J Surg. 2014;101:417–23.CrossRefPubMedCentralPubMed Jacobsen HJ, Nergard BJ, Leifsson BG, et al. Management of suspected anastomotic leak after bariatric laparoscopic Roux-en-Y gastric bypass. Br J Surg. 2014;101:417–23.CrossRefPubMedCentralPubMed
22.
go back to reference Higa K, Ho T, Boone K. Internal hernias after laparoscopic Roux-en-Y gastric bypass: incidence, treatment and prevention. Obes Surg. 2003;13:350–4.CrossRefPubMed Higa K, Ho T, Boone K. Internal hernias after laparoscopic Roux-en-Y gastric bypass: incidence, treatment and prevention. Obes Surg. 2003;13:350–4.CrossRefPubMed
23.
go back to reference Dillemans B, Sakran N, Van Cauwenberge S, et al. Standardization of the fully stapled laparoscopic Roux-en-Y gastric bypass for obesity reduces immediate postoperative morbidity and mortality: a single center study of 2606 patients. Obes Surg. 2009;19:1355–64.CrossRefPubMedCentralPubMed Dillemans B, Sakran N, Van Cauwenberge S, et al. Standardization of the fully stapled laparoscopic Roux-en-Y gastric bypass for obesity reduces immediate postoperative morbidity and mortality: a single center study of 2606 patients. Obes Surg. 2009;19:1355–64.CrossRefPubMedCentralPubMed
24.
go back to reference Suter M, Calmes JM, Paroz A, et al. Results of Roux-en-Y gastric bypass in morbidly obese vs superobese patients. Arch Surg. 2009;144:312–8.CrossRefPubMed Suter M, Calmes JM, Paroz A, et al. Results of Roux-en-Y gastric bypass in morbidly obese vs superobese patients. Arch Surg. 2009;144:312–8.CrossRefPubMed
25.
go back to reference Rieu PN, Jansen JB, Biemond I, et al. Short-term results of gastrectomy with Roux-en-Y or Billroth II anastomosis for peptic ulcer. A prospective comparative study. Hepato-Gastroenterology. 1992;39(1):22–6.PubMed Rieu PN, Jansen JB, Biemond I, et al. Short-term results of gastrectomy with Roux-en-Y or Billroth II anastomosis for peptic ulcer. A prospective comparative study. Hepato-Gastroenterology. 1992;39(1):22–6.PubMed
26.
go back to reference Paroz A, Calmes JM, Giusti V, et al. Internal hernia after laparoscopic Roux-en-Y gastric bypass for morbid obesity: a continuous challenge in bariatric surgery. Obes Surg. 2006;16:1482–7.CrossRefPubMed Paroz A, Calmes JM, Giusti V, et al. Internal hernia after laparoscopic Roux-en-Y gastric bypass for morbid obesity: a continuous challenge in bariatric surgery. Obes Surg. 2006;16:1482–7.CrossRefPubMed
27.
go back to reference Mason EE, Ito C. Gastric bypass in obesity. Surg Clin N Am. 1967;47:1345–135.PubMed Mason EE, Ito C. Gastric bypass in obesity. Surg Clin N Am. 1967;47:1345–135.PubMed
28.
go back to reference Chevallier JM, Trelles N, Arienzo R, et al. Endoscopic findings after laparoscopic omega loop gastric bypass. Obes Surg. 2011;21:956.CrossRef Chevallier JM, Trelles N, Arienzo R, et al. Endoscopic findings after laparoscopic omega loop gastric bypass. Obes Surg. 2011;21:956.CrossRef
29.
go back to reference Garcia-Caballero M, Carbajo M. One anastomosis gastric bypass, safe and efficient surgical procedure for treating morbid obesity. Nutr Hosp. 2004;19(6):372–5.PubMed Garcia-Caballero M, Carbajo M. One anastomosis gastric bypass, safe and efficient surgical procedure for treating morbid obesity. Nutr Hosp. 2004;19(6):372–5.PubMed
30.
go back to reference Hampel H, Abraham NS, El-Serag HB. Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Ann Intern Med. 2005;143(3):199–211.CrossRefPubMed Hampel H, Abraham NS, El-Serag HB. Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Ann Intern Med. 2005;143(3):199–211.CrossRefPubMed
31.
go back to reference Erichsen R, Robertson D, Farkas DK, et al. Erosive reflux disease increases risk for esophageal adenocarcinoma, compared with non erosive reflux. Clin Gastroenterol Hepatol. 2012;10(5):475–80.CrossRefPubMed Erichsen R, Robertson D, Farkas DK, et al. Erosive reflux disease increases risk for esophageal adenocarcinoma, compared with non erosive reflux. Clin Gastroenterol Hepatol. 2012;10(5):475–80.CrossRefPubMed
32.
go back to reference Korswagen LA, Schrama JG, Bruins Slot W, Hunfeld MA. Adenocarcinoma of the lower esophagus after placement of a gastric band. Obes Surg. 2009;19(3):389–392. 21. Korswagen LA, Schrama JG, Bruins Slot W, Hunfeld MA. Adenocarcinoma of the lower esophagus after placement of a gastric band. Obes Surg. 2009;19(3):389–392. 21.
33.
go back to reference Howard DD. Gastroesophageal reflux after sleeve gastrectomy in morbidly obese patients. Surg Obes Relat Dis. 2011;7(6):709–13.CrossRefPubMed Howard DD. Gastroesophageal reflux after sleeve gastrectomy in morbidly obese patients. Surg Obes Relat Dis. 2011;7(6):709–13.CrossRefPubMed
34.
go back to reference Scozzari G, Trapani R, Toppino M, et al. Esophagogastric cancer after bariatric surgery: systematic review of the literature. Surg Obes Relat Dis. 2013;9:133–42.CrossRefPubMed Scozzari G, Trapani R, Toppino M, et al. Esophagogastric cancer after bariatric surgery: systematic review of the literature. Surg Obes Relat Dis. 2013;9:133–42.CrossRefPubMed
35.
go back to reference Nishijima K, Miwa K, Miyashita T, et al. Impact of the biliary diversion procedure on carcinogenesis in Barrett’s esophagus surgically induced by duodenooesophageal reflux in rats. Ann Surg. 2004;240:57–67.CrossRefPubMedCentralPubMed Nishijima K, Miwa K, Miyashita T, et al. Impact of the biliary diversion procedure on carcinogenesis in Barrett’s esophagus surgically induced by duodenooesophageal reflux in rats. Ann Surg. 2004;240:57–67.CrossRefPubMedCentralPubMed
36.
go back to reference Frantz JD, Bretton G, Cartwright ME, et al. Proliferative lesions of the non-glandular and glandular stomach of rats . In: Guides for Toxicologic Pathology STP/ARF/AFIP, Washington,DC,1991. Frantz JD, Bretton G, Cartwright ME, et al. Proliferative lesions of the non-glandular and glandular stomach of rats . In: Guides for Toxicologic Pathology STP/ARF/AFIP, Washington,DC,1991.
37.
go back to reference Bassily R, Smallwood RA, Crotty B. Risk of gastric cancer is not increased after partial gastrectomy. J Gastroenterol Hepatol. 2000;15:762–5.CrossRefPubMed Bassily R, Smallwood RA, Crotty B. Risk of gastric cancer is not increased after partial gastrectomy. J Gastroenterol Hepatol. 2000;15:762–5.CrossRefPubMed
38.
go back to reference Csendes A, Burgos AM, Smok G, et al. Latest results (12–21 years) of a prospective randomized study comparing Billroth II and Roux-en-Y anastomosis after a partial gastrectomy plus vagotomy in patients with duodenal ulcers. Ann Surg. 2009;249:189–94.CrossRefPubMed Csendes A, Burgos AM, Smok G, et al. Latest results (12–21 years) of a prospective randomized study comparing Billroth II and Roux-en-Y anastomosis after a partial gastrectomy plus vagotomy in patients with duodenal ulcers. Ann Surg. 2009;249:189–94.CrossRefPubMed
39.
go back to reference Ito M, Takata S, Tatsugami M, et al. Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review. J Gastroenterol. 2009;44:365–71.CrossRefPubMed Ito M, Takata S, Tatsugami M, et al. Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review. J Gastroenterol. 2009;44:365–71.CrossRefPubMed
40.
go back to reference Chun-Chi Wu, Wei-Jei Lee, Long-Han Ser, et al. Gastric cancer after mini-gastric bypass surgery: A case report and literature review. Asian J Endosc Surg. 2013;303–306. Chun-Chi Wu, Wei-Jei Lee, Long-Han Ser, et al. Gastric cancer after mini-gastric bypass surgery: A case report and literature review. Asian J Endosc Surg. 2013;303–306.
42.
43.
go back to reference Kalfarentzos F, Skroubis G, Karamanakos S, et al. Biliopancreatic diversion with Roux-en-Y gastric bypass and long limbs: advances in surgical treatment for superobesity. Obes Surg. 2011;21:1849–58.CrossRefPubMed Kalfarentzos F, Skroubis G, Karamanakos S, et al. Biliopancreatic diversion with Roux-en-Y gastric bypass and long limbs: advances in surgical treatment for superobesity. Obes Surg. 2011;21:1849–58.CrossRefPubMed
44.
go back to reference Padwal R, Klarenbach S, Wiebe N, et al. Bariatric surgery: a systematic review and network metaanalysis of randomized trials. Obes Rev. 2011;12:602–21.CrossRefPubMed Padwal R, Klarenbach S, Wiebe N, et al. Bariatric surgery: a systematic review and network metaanalysis of randomized trials. Obes Rev. 2011;12:602–21.CrossRefPubMed
Metadata
Title
One Thousand Single Anastomosis (Omega Loop) Gastric Bypasses to Treat Morbid Obesity in a 7-Year Period: Outcomes Show Few Complications and Good Efficacy
Authors
Jean Marc Chevallier
Gustavo A. Arman
Martino Guenzi
Cedric Rau
Mathieu Bruzzi
Nathan Beaupel
Frank Zinzindohoué
Anne Berger
Publication date
01-06-2015
Publisher
Springer US
Published in
Obesity Surgery / Issue 6/2015
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-014-1552-z

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