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Obesity Surgery
Published in: Obesity Surgery 1/2012

Open Access 01-01-2012 | Clinical Report

The Influence of Laparoscopic Sleeve Gastrectomy on Metabolic Syndrome Parameters in Obese Patients in Own Material

Authors: Hady Razak Hady, Jacek Dadan, Magdalena Luba

Published in: Obesity Surgery | Issue 1/2012

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Abstract

Popularity of laparoscopic sleeve gastrectomy (LSG) has been growing gradually. The aim of this study was to determine changes in metabolic syndrome parameters as well as insulin, total cholesterol, and LDL cholesterol, and to describe the influence of body weight loss on co-morbidities in obese patients after LSG with 1-year follow-up. The material consists of 130 patients who underwent LSG (2007–2010) in order to treat morbid obesity and who had met before the surgery at least three criteria necessary for the diagnosis of metabolic syndrome according to the International Diabetes Federation. The influence of LSG on co-morbidities was also analyzed. During 1-year follow-up after LSG, we obtained a statistically significant decrease in BMI (from 53.18 ± 7.5 kg/m2 to 31.4 ± 3.75 kg/m2, p < 0.00001) and a reduction in waist circumference. Twelve months after the surgery, excess weight loss (EWL) was 59.42 ± 7.21% and excess body mass index loss (EBL) was 61.03 ± 6.50%. One year after LSG, the amount of patients with diagnosed metabolic syndrome decreased in 61 patients (53.08%). After 1 year, none of the patients met five criteria of metabolic syndrome. According to efficiency in body mass loss presented by %EWL and %EBL, LSG is gaining approval as a method of obesity and metabolic syndrome treatment, although it is a relatively new procedure. LSG is rather an easy procedure; the time of performance and hospitalization are shorter which entails normalization in all parameters of metabolic syndrome and decreases the percentage of obese patients with metabolic syndrome.
Literature
1.
Finucane MM, Stevens GA, Cowan MJ, et al. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet. 2011;377:557–67.PubMedCrossRef
2.
3.
4.
DeFronzo RA, Ferrannini E. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care. 1991;14:173–94.PubMedCrossRef
5.
Kaplan NM. The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Arch Intern Med. 1989;149:1514–20.PubMedCrossRef
6.
Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15:539–53.PubMedCrossRef
7.
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung and Blood Institute Scientific Statement. Circulation. 2005;112:2735–52.PubMedCrossRef
8.
9.
Wyrzykowski B, Zdrojewski T, Syganowska E. Epidemiology of metabolic syndrome in Poland. Results of the WOBASZ Program. Kardiol Pol. 2005;63:S1–4.
10.
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults. Findings from the Third National Health and Nutrition Examination Survey. JAMA. 2002;287:356–9.PubMedCrossRef
11.
Hu G, Qiao Q, Tuomilehto J, et al. Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women. Arch Intern Med. 2004;164:1066–76.PubMedCrossRef
12.
Isoma B, Almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care. 2001;24:683–9.CrossRef
13.
Lakka HM, Laaksonen DE, Lakka TA, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA. 2002;288:2709–16.PubMedCrossRef
14.
Vidal J, Ibarzabal A, Romero F, et al. Type 2 diabetes mellitus and the metabolic syndrome following sleeve gastrectomy in severely obese subjects. Obes Surg. 2008;18(9):1077–82.PubMedCrossRef
15.
Hess DS, Hess DW. Biliopancreatic diversion with a duodenal switch. Obes Surg. 1988;8:267–82.CrossRef
16.
Johnston D, Dachtler J, Sue-Ling HM, et al. The Magenstrasse and Mill operation for morbid obesity. Obes Surg. 2003;13:10–6.PubMedCrossRef
17.
Ren CJ, Patterson E, Gagner M. Early results of laparoscopic biliopancreatic diversion with duodenal switch: a case series of 40 consecutive patients. Obes Surg. 2000;10:514–23.PubMedCrossRef
18.
Shi X, Karmali S, Sharma. A review of laparoscopic sleeve gastrectomy for morbid obesity. Obes Surg. 2010;20:1171–7.PubMedCrossRef
19.
Buchwald H, Avidor Y, Brawnwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292:1724–37.PubMedCrossRef
20.
Kral JG, Naslund E. Surgical treatment of obesity. Nat Clin Pract Endocrinol Metab. 2007;3:574–83.PubMedCrossRef
21.
Malik S, Wong ND, Franklin SS, et al. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation. 2004;110:1245–50.PubMedCrossRef
22.
Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome. A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640–05.PubMedCrossRef
23.
Jonsson S, Hedblad B, Engström G, et al. Influence of obesity on cardiovascular risk. Twenty-three-year follow-up of 22025 men from an urban Swedish population. Int J Obes Relat Metab Disord. 2002;26:1046–53.PubMedCrossRef
24.
Scott CL. Diagnosis, prevention, and intervention for the metabolic syndrome. Am J Cardiol. 2003;92:35–42.CrossRef
25.
Gracia-Solanas JA, Elia M, Aguilella V, et al. Metabolic syndrome after bariatric surgery. Results depending on the technique performed. Obes Surg. 2011;21:179–85.PubMedCrossRef
26.
Kwiatkowski A, Pasnik K, Stanowski E, et al. Regression of metabolic syndrome depending on type of bariatric surgery. Videosurgery and other miniinvasive techniques. 2009;4(2):53–8.
27.
Karamanakos SN, Vegenas K, Kalfarenteos F, et al. Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study. Ann Surg. 2009;247(3):401–7.CrossRef
28.
Shi X, Karmali S, Sharma AM, et al. A review of laparoscopic sleeve gastrectomy for morbid obesity. Obes Surg. 2010;20:1171–7.PubMedCrossRef
29.
Nocca D, Krawczykowsky D, Bomans B, et al. A prospective multicenter study of 163 sleeve gastrectomies; results at 1 and 2 years. Obes Surg. 2008;18:560–5.PubMedCrossRef
30.
Himpens J, Dobbeleir J, Peeters G. Long-term results of laparoscopic sleeve gastrectomy for obesity. Ann Surg. 2010;252:319–24.PubMedCrossRef
31.
Clinical Issues Committee of the American Society for Metabolic and Bariatric Surgery. Sleeve gastrectomy as a bariatric procedure. Surg Obes Relat Dis. 2007;3:573–6.CrossRef
32.
Armstrong J, O'Malley SP. Outcomes of sleeve gastrectomy for morbid obesity. A safe and effective procedure? Int J Surg. 2010;8:69–71.PubMedCrossRef
33.
Silecchia G, Boru C, Pecchia A, et al. Effectiveness of laparoscopic sleeve gastrectomy. Obes Surg. 2006;16:1138–44.PubMedCrossRef
34.
Rosenthal R, Li X, Samuel S, et al. Effect of sleeve gastrectomy on patients with diabetes mellitus. Surg Obes Relat Dis. 2009;5:429–34.PubMedCrossRef
35.
Assimakopoulos K, Karaivazoglou K, Panayiotopoulos S. Bariatric surgery is associated with reduced depressive symptoms and better sexual function in obese female patients: a one-year follow-up study. Obes Surg. 2011;21(3);362–6.
36.
Brethauer SA, Hammel JP, Schauer PR. Systematic review of sleeve gastrectomy as staging and primary bariatric procedure. Surg Obes Relat Dis. 2009;5(4):469–75.PubMedCrossRef
37.
Feng Z, Strain W, Lei W, et al. Changes in lipid profiles in morbidly obese patients after laparoscopic sleeve gastrectomy. Obes Surg. 2011;21:305–9.CrossRef
Metadata
Title
The Influence of Laparoscopic Sleeve Gastrectomy on Metabolic Syndrome Parameters in Obese Patients in Own Material
Authors
Hady Razak Hady
Jacek Dadan
Magdalena Luba
Publication date
01-01-2012
Publisher
Springer-Verlag
Published in
Obesity Surgery / Issue 1/2012
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-011-0530-y

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