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Archives of Osteoporosis

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01-12-2017 | Original Article

Impact of air pollution on vitamin D deficiency and bone health in adolescents

Authors: Elham Feizabad, Arash Hossein-nezhad, Zhila Maghbooli, Majid Ramezani, Roxana Hashemian, Syamak Moattari

Published in: Archives of Osteoporosis | Issue 1/2017

Abstract

Summary

The association between air pollution and bone health was evaluated in adolescents in the city of Tehran. This study is essentially ecological. Vitamin D deficiency among adolescents has been reported at higher rates in polluted areas than in non-polluted areas. Additionally, residence in polluted areas is associated with lower levels of bone alkaline phosphatase.

Purpose

The aim of this study was to evaluate the association between ambient air pollution and bone turnover in adolescents and to compare the prevalence of vitamin D deficiency between polluted and non-polluted areas of Tehran.

Methods

This cross-sectional population-based study was conducted on 325 middle- and high-school students (both girls and boys) in Tehran in the winter. During the study period, detailed daily data on air pollution were obtained from archived data collected by Tehran Air Quality Control Company (AQCC). Serum levels of calcium, phosphorus, parathyroid hormone (PTH), bone-specific alkaline phosphatase, 25(OH) vitamin D, osteocalcin, cross-linked C-telopeptide (CTX), total protein, albumin, and creatinine were obtained from the study group.

Results

Vitamin D deficiency was more prevalent in polluted areas than in non-polluted areas. After adjustment for age and sex, residence in the polluted area showed a statistically significant positive association with vitamin D deficiency and a statistically significant negative association with bone turnover. Interestingly, high calcium intake (>5000 mg/week) protects against the effects of air pollution on bone turnover.

Conclusions

Air pollution is a chief factor determining the amount of solar UVB that reaches the earth’s surface. Thus, atmospheric pollution may play a significant independent role in the development of vitamin D deficiency.

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Title: Impact of air pollution on vitamin D deficiency and bone health in adolescents
Authors: Elham Feizabad
Arash Hossein-nezhad
Zhila Maghbooli
Majid Ramezani
Roxana Hashemian
Syamak Moattari
Publication date: 01-12-2017
Publisher: Springer London
Published in: Archives of Osteoporosis / Issue 1/2017
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-017-0323-6

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Impact of air pollution on vitamin D deficiency and bone health in adolescents

Abstract

Summary

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Summary

Purpose

Methods

Results

Conclusions

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