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Archives of Osteoporosis

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01-12-2015 | Case Report

Risedronate as an intra-abdominal sepsis mimic: a case report

Authors: Sonali Shah, Cameron Jeremiah, Douglas Johnson, Scott Baker

Published in: Archives of Osteoporosis | Issue 1/2015

Abstract

Summary

This case report highlights the potential severity of bisphosphonate-associated reactions.

Case report

A 76-year-old lady underwent several hospital admissions for investigation of fever associated with rigors, abdominal pain, and vomiting.

Discussion

Despite multiple investigations, no cause was found, but the timing of the symptoms coincided with monthly risedronate administration.

Royal Australian College of General Practitioners (2010) Clinical guideline for the prevention and treatment of osteoporosis in postmenopausal women and older women

Reginster J-Y, Minne HW, Sorensen OH, Hooper M, Roux C, Brandi ML, Lund B, Ethgen D, Pack S, Roumagnac I, Eastell R, on behalf of the Vertebral Efficacy with Risedronate Therapy (VERT) Study Group (2000) Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Osteoporos Int 11(1):83–91PubMedCrossRef

Kennel KA, Drake MT (2009) Adverse effects of bisphosphonates: implications for osteoporosis management. Mayo Clin Proc 84(7):632–638PubMedPubMedCentralCrossRef

Hagino H, Kishimoto H, Ohishi H, Horii S, Nakamura T (2014) Efficacy, tolerability and safety of once-monthly administration of 75 mg risedronate in Japanese patients with involutional osteoporosis: a comparison with a 2.5 mg once-daily dosage regimen. Bone 59:44–52. doi:10.1016/j.bone.2013.10.017 PubMedCrossRef

McClung MR, Zanchetta JR, Racewicz A, Roux C, Benhamou C-L, Man Z, Eusebio RA, Beary JF, Burgio DE, Matzkin E, Boonen S, Delmas P (2013) Efficacy and safety of risedronate 150-mg once a month in the treatment of postmenopausal osteoporosis: 2-year data. Osteoporos Int 24(1):293–299PubMedPubMedCentralCrossRef

Title: Risedronate as an intra-abdominal sepsis mimic: a case report
Authors: Sonali Shah
Cameron Jeremiah
Douglas Johnson
Scott Baker
Publication date: 01-12-2015
Publisher: Springer London
Published in: Archives of Osteoporosis / Issue 1/2015
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-015-0213-8

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Springer Medicine

Risedronate as an intra-abdominal sepsis mimic: a case report

Abstract

Summary

Case report

Discussion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Summary

Case report

Discussion

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