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Journal of General Internal Medicine
Published in: Journal of General Internal Medicine 8/2021

01-08-2021 | Acute Kidney Injury | Concise Research Report

The Association Between Convalescent Plasma Treatment and Survival of Patients with COVID-19

Authors: Toshiki Kuno, MD, PhD, Mai Takahashi, MD, MPH, Natalia N. Egorova, PhD, MPH

Published in: Journal of General Internal Medicine | Issue 8/2021

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Excerpt

Various treatments of COVID-19 including the infusion of plasma of convalescent patients are still researched, especially for moderate and severe cases.1‐3 The published studies report conflicting efficacy of the treatment with plasma. One randomized trial showed that early administration of convalescent plasma might be effective in elderly patients3 while another trial did not reveal the reduction in mortality.1,2 …
Literature
1.
Li L, Zhang W, Hu Y et al. Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial. JAMA 2020;324:460-470.CrossRef
2.
Agarwal A, Mukherjee A, Kumar G et al. Convalescent plasma in the management of moderate covid-19 in adults in India: open label phase II multicentre randomised controlled trial (PLACID Trial). BMJ 2020;371:m3939.CrossRef
3.
Libster R, Perez Marc G, Wappner D et al. Early high-titer plasma therapy to prevent severe COVID-19 in older adults. N Engl J Med 2021;384:610-618.CrossRef
4.
Chandiramani R, Cao D, Nicolas J, Mehran R. Contrast-induced acute kidney injury. Cardiovasc Interv Ther 2020;35:209-217.CrossRef
5.
Group WHOREAfC-TW, Sterne JAC, Murthy S et al. Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis. JAMA 2020;324:1330-1341.CrossRef
6.
Joyner MJ, Carter RE, Senefeld JW et al. Convalescent plasma antibody levels and the risk of death from COVID-19. N Engl J Med 2021.
Metadata
Title
The Association Between Convalescent Plasma Treatment and Survival of Patients with COVID-19
Authors
Toshiki Kuno, MD, PhD
Mai Takahashi, MD, MPH
Natalia N. Egorova, PhD, MPH
Publication date
01-08-2021
Publisher
Springer International Publishing
Published in
Journal of General Internal Medicine / Issue 8/2021
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-021-06894-3

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