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Published in: Journal of General Internal Medicine 1/2022

01-01-2022 | Burnout Syndrome | Original Research

Depressive Symptoms and Burnout Among Medical Students: a Prospective Study

Authors: Padmini D. Ranasinghe, MD, MPH, Jocelynn T. Owusu, PhD, MPH, Amanda Bertram, MS, Henry Michtalik, MD, MPH, Hsin-Chieh Yeh, PhD, Joseph Cofrancesco Jr, MD, MPH, David Levine, MD, PHD, Edgar R. Miller III, MD, PhD, Spyridon Marinopoulos, MD, MBA

Published in: Journal of General Internal Medicine | Issue 1/2022

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Abstract

Background

Depressive symptoms and burnout are common among medical students. However, few studies have investigated their trajectory over the course of medical school.

Objective

Evaluate year-by-year changes in depressive and burnout symptoms over the course of medical school training.

Design

Prospective study.

Participants

Medical students who matriculated at a private medical school in Maryland from 2010 to 2016 (n=758).

Main Measures

Clinically significant depressive symptoms were defined as a score of ≥10 on the 9-item Patient Health Questionnaire (PHQ-9), and burnout was measured using the Maslach Burnout Inventory (MBI). High emotional exhaustion, high depersonalization, and low personal accomplishment were defined as scores of ≥ 27, ≥10, and ≤33 on the respective MBI subscales.

Key Results

At matriculation, the prevalences of significant depressive symptoms, high emotional exhaustion, high depersonalization, and low personal accomplishment were 4.3%, 9.4%, 8.6%, and 37.7%, respectively. After adjustment for age, sex, race/ethnicity, marital status, and cohort, compared with year 1, the odds of significant depressive symptoms was significantly higher at the beginning of the 2nd, 3rd, and 4th years of study (ORs=2.63, 2.85, and 3.77, respectively; all ps<0.001). Compared with the 1st year, the odds of high emotional exhaustion also increased during the 2nd, 3rd, and 4th years of study, (ORs=3.46, 4.79, 8.20, respectively; all ps<0.001), as did the odds of high depersonalization (ORs=3.55, 6.14, 12.53, respectively; all ps<0.001). The odds of low personal accomplishment did not significantly differ across years of study.

Conclusions

The results of this study suggest that symptoms of depression and burnout may increase during medical school. Because of the high prevalence of depressive symptoms and burnout in medical students, interventions earlier in the medical career pathway that aim to prevent, detect, and treat these symptoms may be of benefit to the physician community.
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Literature
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go back to reference Dyrbye LN, Thomas MR, Shanafelt TD. Systematic review of depression, anxiety, and other indicators of psychological distress among U.S. and Canadian medical students. Acad Med. Apr 2006;81(4):354-73.CrossRefPubMed Dyrbye LN, Thomas MR, Shanafelt TD. Systematic review of depression, anxiety, and other indicators of psychological distress among U.S. and Canadian medical students. Acad Med. Apr 2006;81(4):354-73.CrossRefPubMed
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go back to reference Maslach C, Jackson S, Leiter MP. Maslach Burnout Inventory Manual. 3rd ed. Consulting Psychologists Press; 1996. Maslach C, Jackson S, Leiter MP. Maslach Burnout Inventory Manual. 3rd ed. Consulting Psychologists Press; 1996.
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go back to reference Fitzpatrick O, Biesma R, Conroy RM, McGarvey A. Prevalence and relationship between burnout and depression in our future doctors: a cross-sectional study in a cohort of preclinical and clinical medical students in Ireland. BMJ Open. 05 2019;9(4):e023297. https://doi.org/10.1136/bmjopen-2018-023297 Fitzpatrick O, Biesma R, Conroy RM, McGarvey A. Prevalence and relationship between burnout and depression in our future doctors: a cross-sectional study in a cohort of preclinical and clinical medical students in Ireland. BMJ Open. 05 2019;9(4):e023297. https://​doi.​org/​10.​1136/​bmjopen-2018-023297
Metadata
Title
Depressive Symptoms and Burnout Among Medical Students: a Prospective Study
Authors
Padmini D. Ranasinghe, MD, MPH
Jocelynn T. Owusu, PhD, MPH
Amanda Bertram, MS
Henry Michtalik, MD, MPH
Hsin-Chieh Yeh, PhD
Joseph Cofrancesco Jr, MD, MPH
David Levine, MD, PHD
Edgar R. Miller III, MD, PhD
Spyridon Marinopoulos, MD, MBA
Publication date
01-01-2022
Publisher
Springer International Publishing
Published in
Journal of General Internal Medicine / Issue 1/2022
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-021-06765-x

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