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01-10-2020 | Concise Research Report

Research Waste in Randomized Clinical Trials: a Cross-Sectional Analysis

Authors: Alexander R Zheutlin, Joshua Niforatos, Eric Stulberg, Jeremy Sussman

Published in: Journal of General Internal Medicine | Issue 10/2020

Excerpt

Randomized clinical trials (RCT) require substantial investments from patients, investigators, and funding agencies. RCTs that fail to be completed or to report findings represent research waste, and unnecessary patient harm. Determining RCT viability is critical in allocating funds, and ClinicalTrials.gov provides a platform for investigators to post results from completed RCTs irrespective of “success,” which can influence publication.¹ We sought to describe research waste in Phase 3 RCTs as indicated by inability to reach completion and insufficient reporting of results when completed. …

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Title: Research Waste in Randomized Clinical Trials: a Cross-Sectional Analysis
Authors: Alexander R Zheutlin
Joshua Niforatos
Eric Stulberg
Jeremy Sussman
Publication date: 01-10-2020
Publisher: Springer International Publishing
Published in: Journal of General Internal Medicine / Issue 10/2020
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI: https://doi.org/10.1007/s11606-019-05523-4

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