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Published in: Journal of General Internal Medicine 12/2019

01-12-2019 | Addiction | Original Research

Inpatient Addiction Medicine Consultation and Post-Hospital Substance Use Disorder Treatment Engagement: a Propensity-Matched Analysis

Authors: Honora Englander, MD, Konrad Dobbertin, MPH, Bonnie K. Lind, PhD, Christina Nicolaidis, MD, MPH, Peter Graven, PhD, Claire Dorfman, BA, P. Todd Korthuis, MD, MPH

Published in: Journal of General Internal Medicine | Issue 12/2019

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Abstract

Background

Hospitalizations due to medical and surgical complications of substance use disorder (SUD) are rising. Most hospitals lack systems to treat SUD, and most people with SUD do not engage in treatment after discharge.

Objective

Determine the effect of a hospital-based addiction medicine consult service, the Improving Addiction Care Team (IMPACT), on post-hospital SUD treatment engagement.

Design

Cohort study using multivariable analysis of Oregon Medicaid claims comparing IMPACT patients with propensity-matched controls.

Participants

18–64-year-old Oregon Medicaid beneficiaries with SUD, hospitalized at an Oregon hospital between July 1, 2015, and September 30, 2016. IMPACT patients (n = 208) were matched to controls (n = 416) using a propensity score that accounted for SUD, gender, age, race, residence region, and diagnoses.

Interventions

IMPACT included hospital-based consultation care from an interdisciplinary team of addiction medicine physicians, social workers, and peers with lived experience in recovery. IMPACT met patients during hospitalization; offered pharmacotherapy, behavioral treatments, and harm reduction services; and supported linkages to SUD treatment after discharge.

Outcomes

Healthcare Effectiveness Data and Information Set (HEDIS) measure of SUD treatment engagement, defined as two or more claims on two separate days for SUD care within 34 days of discharge.

Results

Only 17.2% of all patients were engaged in SUD treatment before hospitalization. IMPACT patients engaged in SUD treatment following discharge more frequently than controls (38.9% vs. 23.3%, p < 0.01; aOR 2.15, 95% confidence interval [CI] 1.29–3.58). IMPACT participation remained associated with SUD treatment engagement when limiting the sample to people who were not engaged in treatment prior to hospitalization (aOR 2.63; 95% CI 1.46–4.72).

Conclusions

Hospital-based addiction medicine consultation can improve SUD treatment engagement, which is associated with reduced substance use, mortality, and other important clinical outcomes. National expansion of such models represents an opportunity to address an enduring gap in the SUD treatment continuum.
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Literature
1.
go back to reference Tedesco D, Asch SM, Curtin C, Hah J, McDonald KM, Fantini MP, et al. Opioid abuse and poisoning: trends in inpatient and emergency department discharges. Health Aff (Millwood) 2017;36(10):1748–53. Tedesco D, Asch SM, Curtin C, Hah J, McDonald KM, Fantini MP, et al. Opioid abuse and poisoning: trends in inpatient and emergency department discharges. Health Aff (Millwood) 2017;36(10):1748–53.
2.
go back to reference Ronan MV, Herzig SJ. Hospitalizations related to opioid abuse/dependence and associated serious infections increased sharply, 2002-12. Health Aff (Millwood) 2016;35(5):832–7. Ronan MV, Herzig SJ. Hospitalizations related to opioid abuse/dependence and associated serious infections increased sharply, 2002-12. Health Aff (Millwood) 2016;35(5):832–7.
3.
go back to reference Walley AY, Paasche-Orlow M, Lee EC, Forsythe S, Chetty VK, Mitchell S, et al. Acute care hospital utilization among medical inpatients discharged with a substance use disorder diagnosis. J Addict Med 2012;6(1):50–6.PubMedPubMedCentral Walley AY, Paasche-Orlow M, Lee EC, Forsythe S, Chetty VK, Mitchell S, et al. Acute care hospital utilization among medical inpatients discharged with a substance use disorder diagnosis. J Addict Med 2012;6(1):50–6.PubMedPubMedCentral
5.
go back to reference Winkelman TA, Admon LK, Jennings L, Shippee ND, Richardson CR, Bart G. Evaluation of amphetamine-related hospitalizations and associated clinical outcomes and costs in the United States. JAMA Netw Open 2018;1(6):e183758.PubMedPubMedCentral Winkelman TA, Admon LK, Jennings L, Shippee ND, Richardson CR, Bart G. Evaluation of amphetamine-related hospitalizations and associated clinical outcomes and costs in the United States. JAMA Netw Open 2018;1(6):e183758.PubMedPubMedCentral
7.
go back to reference Naeger S, Ali MM, Mutter R, Mark TL, Hughey L. Prescriptions filled following an opioid-related hospitalization. Psychiatr Serv 2016;67(11):1262–4.PubMed Naeger S, Ali MM, Mutter R, Mark TL, Hughey L. Prescriptions filled following an opioid-related hospitalization. Psychiatr Serv 2016;67(11):1262–4.PubMed
8.
go back to reference Englander H, Collins D, Perry SP, Rabinowitz M, Phoutrides E, Nicolaidis C. “We’ve learned it’s a medical illness, not a moral choice”: qualitative study of the effects of a multicomponent addiction intervention on hospital providers’ attitudes and experiences. J Hosp Med 2018;13(11):752–8.PubMed Englander H, Collins D, Perry SP, Rabinowitz M, Phoutrides E, Nicolaidis C. “We’ve learned it’s a medical illness, not a moral choice”: qualitative study of the effects of a multicomponent addiction intervention on hospital providers’ attitudes and experiences. J Hosp Med 2018;13(11):752–8.PubMed
9.
go back to reference Ti L, Ti L. Leaving the hospital against medical advice among people who use illicit drugs: a systematic review. Am J Public Health 2015;105(12):e53–9.PubMedPubMedCentral Ti L, Ti L. Leaving the hospital against medical advice among people who use illicit drugs: a systematic review. Am J Public Health 2015;105(12):e53–9.PubMedPubMedCentral
10.
go back to reference McNeil R, Small W, Wood E, Kerr T. Hospitals as a ‘risk environment’: an ethno-epidemiological study of voluntary and involuntary discharge from hospital against medical advice among people who inject drugs. Soc Sci Med 2014;105:59–66.PubMedPubMedCentral McNeil R, Small W, Wood E, Kerr T. Hospitals as a ‘risk environment’: an ethno-epidemiological study of voluntary and involuntary discharge from hospital against medical advice among people who inject drugs. Soc Sci Med 2014;105:59–66.PubMedPubMedCentral
11.
go back to reference Sordo L, Barrio G, Bravo MJ, Indave BI, Degenhardt L, Wiessing L, et al. Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies. BMJ (Clinical research ed). 2017;357:j1550. Sordo L, Barrio G, Bravo MJ, Indave BI, Degenhardt L, Wiessing L, et al. Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies. BMJ (Clinical research ed). 2017;357:j1550.
12.
go back to reference Jonas DE, Amick HR, Feltner C, Bobashev G, Thomas K, Wines R, et al. Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis. JAMA. 2014;311(18):1889–900.PubMed Jonas DE, Amick HR, Feltner C, Bobashev G, Thomas K, Wines R, et al. Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis. JAMA. 2014;311(18):1889–900.PubMed
13.
go back to reference Rosenthal ES, Karchmer AW, Theisen-Toupal J, Castillo RA, Rowley CF. Suboptimal addiction interventions for patients hospitalized with injection drug use-associated infective endocarditis. Am J Med 2016;129(5):481–5.PubMed Rosenthal ES, Karchmer AW, Theisen-Toupal J, Castillo RA, Rowley CF. Suboptimal addiction interventions for patients hospitalized with injection drug use-associated infective endocarditis. Am J Med 2016;129(5):481–5.PubMed
14.
go back to reference Winetsky D, Weinrieb RM, Perrone J. Expanding treatment opportunities for hospitalized patients with opioid use disorders. J Hosp Med 2018;13(1):62–4.PubMed Winetsky D, Weinrieb RM, Perrone J. Expanding treatment opportunities for hospitalized patients with opioid use disorders. J Hosp Med 2018;13(1):62–4.PubMed
15.
go back to reference Saitz R. Treatment for opioid addiction must be offered in general hospitals: but how? J Addict Med 2019;13(2):83–4.PubMed Saitz R. Treatment for opioid addiction must be offered in general hospitals: but how? J Addict Med 2019;13(2):83–4.PubMed
16.
go back to reference D’Onofrio G, O’Connor PG, Pantalon MV, Chawarski MC, Busch SH, Owens PH, et al. Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial. Jama. 2015;313(16):1636–44.PubMedPubMedCentral D’Onofrio G, O’Connor PG, Pantalon MV, Chawarski MC, Busch SH, Owens PH, et al. Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial. Jama. 2015;313(16):1636–44.PubMedPubMedCentral
17.
go back to reference Merrall EL, Bird SM, Hutchinson SJ. A record-linkage study of drug-related death and suicide after hospital discharge among drug-treatment clients in Scotland, 1996–2006. Addiction 2013;108(2):377–84.PubMed Merrall EL, Bird SM, Hutchinson SJ. A record-linkage study of drug-related death and suicide after hospital discharge among drug-treatment clients in Scotland, 1996–2006. Addiction 2013;108(2):377–84.PubMed
18.
go back to reference Mattick RP, Breen C, Kimber J, Davoli M. Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. Cochrane Database Syst Rev 2014;(2):CD002207. Mattick RP, Breen C, Kimber J, Davoli M. Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. Cochrane Database Syst Rev 2014;(2):CD002207.
19.
go back to reference Nielsen S, Larance B, Degenhardt L, Gowing L, Kehler C, Lintzeris N. Opioid agonist treatment for pharmaceutical opioid dependent people. Cochrane Database Syst Rev 2016;(5):Cd011117. Nielsen S, Larance B, Degenhardt L, Gowing L, Kehler C, Lintzeris N. Opioid agonist treatment for pharmaceutical opioid dependent people. Cochrane Database Syst Rev 2016;(5):Cd011117.
20.
go back to reference Saxon AJ, Ling W, Hillhouse M, Thomas C, Hasson A, Ang A, et al. Buprenorphine/naloxone and methadone effects on laboratory indices of liver health: a randomized trial. Drug Alcohol Depend 2013;128(1–2):71–6.PubMed Saxon AJ, Ling W, Hillhouse M, Thomas C, Hasson A, Ang A, et al. Buprenorphine/naloxone and methadone effects on laboratory indices of liver health: a randomized trial. Drug Alcohol Depend 2013;128(1–2):71–6.PubMed
21.
go back to reference Harris AH, Humphreys K, Bowe T, Tiet Q, Finney JW. Does meeting the HEDIS substance abuse treatment engagement criterion predict patient outcomes? J Behav Health Serv Res 2010;37(1):25–39.PubMed Harris AH, Humphreys K, Bowe T, Tiet Q, Finney JW. Does meeting the HEDIS substance abuse treatment engagement criterion predict patient outcomes? J Behav Health Serv Res 2010;37(1):25–39.PubMed
22.
go back to reference Arria AM. Drug treatment completion and post-discharge employment in the TOPPS-II Interstate Cooperative Study. J Subst Abus Treat 2003;25(1):9–18. Arria AM. Drug treatment completion and post-discharge employment in the TOPPS-II Interstate Cooperative Study. J Subst Abus Treat 2003;25(1):9–18.
23.
go back to reference Larochelle MR, Liebschutz JM, Zhang F, Ross-Degnan D, Wharam JF. Opioid prescribing after nonfatal overdose and association with repeated overdose: a cohort study. Ann Intern Med 2016;164(1):1–9.PubMed Larochelle MR, Liebschutz JM, Zhang F, Ross-Degnan D, Wharam JF. Opioid prescribing after nonfatal overdose and association with repeated overdose: a cohort study. Ann Intern Med 2016;164(1):1–9.PubMed
24.
go back to reference Englander H, Weimer M, Solotaroff R, Nicolaidis C, Chan B, Velez C, et al. Planning and designing the Improving Addiction Care Team (IMPACT) for hospitalized adults with substance use disorder. J Hosp Med 2017;12(5):339–42.PubMedPubMedCentral Englander H, Weimer M, Solotaroff R, Nicolaidis C, Chan B, Velez C, et al. Planning and designing the Improving Addiction Care Team (IMPACT) for hospitalized adults with substance use disorder. J Hosp Med 2017;12(5):339–42.PubMedPubMedCentral
25.
go back to reference Liebschutz JM, Crooks D, Herman D, Anderson B, Tsui J, Meshesha LZ, et al. Buprenorphine treatment for hospitalized, opioid-dependent patients: a randomized clinical trial. JAMA Intern Med 2014;174(8):1369–76.PubMedPubMedCentral Liebschutz JM, Crooks D, Herman D, Anderson B, Tsui J, Meshesha LZ, et al. Buprenorphine treatment for hospitalized, opioid-dependent patients: a randomized clinical trial. JAMA Intern Med 2014;174(8):1369–76.PubMedPubMedCentral
26.
go back to reference Wakeman SE, Rich JD. Barriers to post-acute care for patients on opioid agonist therapy; an example of systematic stigmatization of addiction. J Gen Intern Med 2017;32(1):17–9.PubMed Wakeman SE, Rich JD. Barriers to post-acute care for patients on opioid agonist therapy; an example of systematic stigmatization of addiction. J Gen Intern Med 2017;32(1):17–9.PubMed
27.
go back to reference Shanahan CW, Beers D, Alford DP, Brigandi E, Samet JH. A transitional opioid program to engage hospitalized drug users. J Gen Intern Med 2010;25(8):803–8.PubMedPubMedCentral Shanahan CW, Beers D, Alford DP, Brigandi E, Samet JH. A transitional opioid program to engage hospitalized drug users. J Gen Intern Med 2010;25(8):803–8.PubMedPubMedCentral
28.
go back to reference Trowbridge P, Weinstein ZM, Kerensky T, Roy P, Regan D, Samet JH, et al. Addiction consultation services - linking hospitalized patients to outpatient addiction treatment. J Subst Abus Treat 2017;79:1–5. Trowbridge P, Weinstein ZM, Kerensky T, Roy P, Regan D, Samet JH, et al. Addiction consultation services - linking hospitalized patients to outpatient addiction treatment. J Subst Abus Treat 2017;79:1–5.
29.
go back to reference Fanucchi L, Lofwall MR. Putting Parity into Practice - Integrating Opioid-Use Disorder Treatment into the Hospital Setting. N Engl J Med 2016;375(9):811–3.PubMed Fanucchi L, Lofwall MR. Putting Parity into Practice - Integrating Opioid-Use Disorder Treatment into the Hospital Setting. N Engl J Med 2016;375(9):811–3.PubMed
30.
go back to reference Wakeman SE, Metlay JP, Chang Y, Herman GE, Rigotti NA. Inpatient addiction consultation for hospitalized patients increases post-discharge abstinence and reduces addiction severity. J Gen Intern Med 2017;32(8):909–16.PubMedPubMedCentral Wakeman SE, Metlay JP, Chang Y, Herman GE, Rigotti NA. Inpatient addiction consultation for hospitalized patients increases post-discharge abstinence and reduces addiction severity. J Gen Intern Med 2017;32(8):909–16.PubMedPubMedCentral
32.
go back to reference Englander H, Mahoney S, Brandt K, Brown J, Dorfman C, Nydahl A, et al. Tools to support hospital-based addiction care: core components, values, and activities of the Improving Addiction Care Team. J Addict Med 2019;13(2):85–9.PubMed Englander H, Mahoney S, Brandt K, Brown J, Dorfman C, Nydahl A, et al. Tools to support hospital-based addiction care: core components, values, and activities of the Improving Addiction Care Team. J Addict Med 2019;13(2):85–9.PubMed
34.
go back to reference Rubin DB. Using multivariate matched sampling and regression adjustment to control bias in observational studies. J Am Stat Assoc 1979;74(366):318–28. Rubin DB. Using multivariate matched sampling and regression adjustment to control bias in observational studies. J Am Stat Assoc 1979;74(366):318–28.
35.
go back to reference Kronick R, Gilmer T, Dreyfus T, Lee L. Improving health-based payment for Medicaid beneficiaries: CDPS. Health Care Financ Rev 2000;21(3):29–64.PubMedPubMedCentral Kronick R, Gilmer T, Dreyfus T, Lee L. Improving health-based payment for Medicaid beneficiaries: CDPS. Health Care Financ Rev 2000;21(3):29–64.PubMedPubMedCentral
38.
go back to reference Socías ME, Wood E, Kerr T, Nolan S, Hayashi K, Nosova E, et al. Trends in engagement in the cascade of care for opioid use disorder, Vancouver, Canada, 2006-2016. Drug Alcohol Depend 2018;189:90–5.PubMedPubMedCentral Socías ME, Wood E, Kerr T, Nolan S, Hayashi K, Nosova E, et al. Trends in engagement in the cascade of care for opioid use disorder, Vancouver, Canada, 2006-2016. Drug Alcohol Depend 2018;189:90–5.PubMedPubMedCentral
39.
go back to reference Dehejia R, Wahba S. Propensity score matching methods for non-experimental causal studies. Rev Econ Stat 2002;84:151–61. Dehejia R, Wahba S. Propensity score matching methods for non-experimental causal studies. Rev Econ Stat 2002;84:151–61.
41.
go back to reference Potier C, Laprevote V, Dubois-Arber F, Cottencin O, Rolland B. Supervised injection services: what has been demonstrated? A systematic literature review. Drug Alcohol Depend 2014;145:48–68.PubMed Potier C, Laprevote V, Dubois-Arber F, Cottencin O, Rolland B. Supervised injection services: what has been demonstrated? A systematic literature review. Drug Alcohol Depend 2014;145:48–68.PubMed
42.
go back to reference Abdul-Quader AS, Feelemyer J, Modi S, Stein ES, Briceno A, Semaan S, et al. Effectiveness of structural-level needle/syringe programs to reduce HCV and HIV infection among people who inject drugs: a systematic review. AIDS Behav 2013;17(9):2878–92.PubMedPubMedCentral Abdul-Quader AS, Feelemyer J, Modi S, Stein ES, Briceno A, Semaan S, et al. Effectiveness of structural-level needle/syringe programs to reduce HCV and HIV infection among people who inject drugs: a systematic review. AIDS Behav 2013;17(9):2878–92.PubMedPubMedCentral
43.
go back to reference Chou R, Korthuis PT, McCarty D, Coffin PO, Griffin JC, Davis-O’Reilly C, et al. Management of suspected opioid overdose with naloxone in out-of-hospital settings: a systematic review. Ann Intern Med 2017;167(12):867–75.PubMed Chou R, Korthuis PT, McCarty D, Coffin PO, Griffin JC, Davis-O’Reilly C, et al. Management of suspected opioid overdose with naloxone in out-of-hospital settings: a systematic review. Ann Intern Med 2017;167(12):867–75.PubMed
44.
go back to reference Thakarar K, Weinstein ZM, Walley AY. Optimising health and safety of people who inject drugs during transition from acute to outpatient care: narrative review with clinical checklist. Postgrad Med J 2016;92(1088):356–63.PubMedPubMedCentral Thakarar K, Weinstein ZM, Walley AY. Optimising health and safety of people who inject drugs during transition from acute to outpatient care: narrative review with clinical checklist. Postgrad Med J 2016;92(1088):356–63.PubMedPubMedCentral
45.
go back to reference Borders TF, Booth BM. Research on rural residence and access to drug abuse services: where are we and where do we go? J Rural Health 2007;23 Suppl:79–83. Borders TF, Booth BM. Research on rural residence and access to drug abuse services: where are we and where do we go? J Rural Health 2007;23 Suppl:79–83.
46.
go back to reference Ziller EC, Anderson NJ, Coburn AF. Access to rural mental health services: service use and out-of-pocket costs. J Rural Health 2010;26(3):214–24.PubMed Ziller EC, Anderson NJ, Coburn AF. Access to rural mental health services: service use and out-of-pocket costs. J Rural Health 2010;26(3):214–24.PubMed
47.
go back to reference Deaton A, Cartwright N. Understanding and misunderstanding randomized controlled trials. Soc Sci Med 2018;210:2–21.PubMed Deaton A, Cartwright N. Understanding and misunderstanding randomized controlled trials. Soc Sci Med 2018;210:2–21.PubMed
48.
go back to reference Frieden TR. Evidence for Health Decision Making - Beyond Randomized, Controlled Trials N Engl J Med 2017;377(5):465–75.PubMed Frieden TR. Evidence for Health Decision Making - Beyond Randomized, Controlled Trials N Engl J Med 2017;377(5):465–75.PubMed
Metadata
Title
Inpatient Addiction Medicine Consultation and Post-Hospital Substance Use Disorder Treatment Engagement: a Propensity-Matched Analysis
Authors
Honora Englander, MD
Konrad Dobbertin, MPH
Bonnie K. Lind, PhD
Christina Nicolaidis, MD, MPH
Peter Graven, PhD
Claire Dorfman, BA
P. Todd Korthuis, MD, MPH
Publication date
01-12-2019
Publisher
Springer US
Published in
Journal of General Internal Medicine / Issue 12/2019
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-019-05251-9

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