Skip to main content
Top
Published in: Journal of General Internal Medicine 10/2018

01-10-2018 | Original Research

Transitions of Care for Postoperative Opioid Prescribing in Previously Opioid-Naïve Patients in the USA: a Retrospective Review

Authors: Michael P. Klueh, BS, Hsou M. Hu, PhD, Ryan A. Howard, MD, Joceline V. Vu, MD, Calista M. Harbaugh, MD, Pooja A. Lagisetty, MD, Chad M. Brummett, MD, Michael J. Englesbe, MD, Jennifer F. Waljee, MD, MPH, MS, Jay S. Lee, MD

Published in: Journal of General Internal Medicine | Issue 10/2018

Login to get access

Abstract

Background

New persistent opioid use is a common postoperative complication, with 6% of previously opioid-naïve patients continuing to fill opioid prescriptions 3–6 months after surgery. Despite these risks, it is unknown which specialties prescribe opioids to these vulnerable patients.

Objective

To identify specialties prescribing opioids to surgical patients who develop new persistent opioid use.

Design, Setting, and Participants

Using a national dataset of insurance claims, we identified opioid-naïve patients aged 18–64 years undergoing surgical procedures (2008–2014) who continued filling opioid prescriptions 3 to 6 months after surgery. We then examined opioid prescriptions claims during the 12 months after surgery, and identified prescribing physician specialty using National Provider Identifier codes.

Main Measures

Percentage of opioid prescriptions provided by each specialty evaluated at 90-day intervals during the 12 months after surgery.

Key Results

We identified 5276 opioid-naïve patients who developed new persistent opioid use. During the first 3 months after surgery, surgeons accounted for 69% of opioid prescriptions, primary care physicians accounted for 13%, Emergency Medicine accounted for 2%, Physical Medicine & Rehabilitation (PM&R)/Pain Medicine accounted for 1%, and all other specialties accounted for 15%. In contrast, 9 to 12 months after surgery, surgeons accounted for only 11% of opioid prescriptions, primary care physicians accounted for 53%, Emergency Medicine accounted for 5%, PM&R/Pain Medicine accounted for 6%, and all other specialties provided 25%.

Conclusions

Among surgical patients who developed new persistent opioid use, surgeons provide the majority of opioid prescriptions during the first 3 months after surgery. By 9 to 12 months after surgery, however, the majority of opioid prescriptions were provided by primary care physicians. Enhanced care coordination between surgeons and primary care physicians could allow earlier identification of patients at risk for new persistent opioid use to prevent misuse and dependence.
Appendix
Available only for authorised users
Literature
1.
go back to reference Thiels CA, Anderson SS, Ubl DS, et al. Wide variation and overprescription of opioids after elective surgery. Ann Surg. 2017. Thiels CA, Anderson SS, Ubl DS, et al. Wide variation and overprescription of opioids after elective surgery. Ann Surg. 2017.
2.
go back to reference Hill MV, McMahon ML, Stucke RS, Barth RJ, Jr. Wide variation and excessive dosage of opioid prescriptions for common general surgical procedures. Ann Surg. 2017;265(4):709–714.CrossRefPubMed Hill MV, McMahon ML, Stucke RS, Barth RJ, Jr. Wide variation and excessive dosage of opioid prescriptions for common general surgical procedures. Ann Surg. 2017;265(4):709–714.CrossRefPubMed
3.
go back to reference Bates C, Laciak R, Southwick A, Bishoff J. Overprescription of postoperative narcotics: a look at postoperative pain medication delivery, consumption and disposal in urological practice. J Urol. 2011;185(2):551–555.CrossRefPubMed Bates C, Laciak R, Southwick A, Bishoff J. Overprescription of postoperative narcotics: a look at postoperative pain medication delivery, consumption and disposal in urological practice. J Urol. 2011;185(2):551–555.CrossRefPubMed
4.
go back to reference Shah A, Hayes CJ, Martin BC. Factors influencing long-term opioid use among opioid naive patients: an examination of initial prescription characteristics and pain etiologies. J Pain. 2017. Shah A, Hayes CJ, Martin BC. Factors influencing long-term opioid use among opioid naive patients: an examination of initial prescription characteristics and pain etiologies. J Pain. 2017.
5.
go back to reference Brummett CM, Waljee JF, Goesling J, et al. New persistent opioid use after minor and major surgical procedures in US adults. JAMA Surg. 2017;152(6):e170504.CrossRefPubMed Brummett CM, Waljee JF, Goesling J, et al. New persistent opioid use after minor and major surgical procedures in US adults. JAMA Surg. 2017;152(6):e170504.CrossRefPubMed
6.
go back to reference Clarke H, Soneji N, Ko DT, Yun L, Wijeysundera DN. Rates and risk factors for prolonged opioid use after major surgery: population based cohort study. BMJ. 2014;348:g1251.CrossRefPubMedPubMedCentral Clarke H, Soneji N, Ko DT, Yun L, Wijeysundera DN. Rates and risk factors for prolonged opioid use after major surgery: population based cohort study. BMJ. 2014;348:g1251.CrossRefPubMedPubMedCentral
7.
go back to reference Soneji N, Clarke HA, Ko DT, Wijeysundera DN. Risks of developing persistent Opioid use after major surgery. JAMA Surg. 2016;151(11):1083–1084.CrossRefPubMed Soneji N, Clarke HA, Ko DT, Wijeysundera DN. Risks of developing persistent Opioid use after major surgery. JAMA Surg. 2016;151(11):1083–1084.CrossRefPubMed
8.
go back to reference Alam A, Gomes T, Zheng H, Mamdani MM, Juurlink DN, Bell CM. Long-term analgesic use after low-risk surgery: a retrospective cohort study. Arch Intern Med. 2012;172(5):425–430.CrossRefPubMed Alam A, Gomes T, Zheng H, Mamdani MM, Juurlink DN, Bell CM. Long-term analgesic use after low-risk surgery: a retrospective cohort study. Arch Intern Med. 2012;172(5):425–430.CrossRefPubMed
9.
go back to reference Kehlet H, Rathmell JP. Persistent postsurgical pain: the path forward through better design of clinical studies. Anesthesiology. 2010;112(3):514–515.CrossRefPubMed Kehlet H, Rathmell JP. Persistent postsurgical pain: the path forward through better design of clinical studies. Anesthesiology. 2010;112(3):514–515.CrossRefPubMed
10.
go back to reference Rudd RA, Seth P, David F, Scholl L. Increases in drug and opioid-involved overdose deaths—United States, 2010-2015. MMWR Morb Mortal Wkly Rep. 2016;65(5051):1445–1452.CrossRefPubMed Rudd RA, Seth P, David F, Scholl L. Increases in drug and opioid-involved overdose deaths—United States, 2010-2015. MMWR Morb Mortal Wkly Rep. 2016;65(5051):1445–1452.CrossRefPubMed
12.
go back to reference Levy B, Paulozzi L, Mack KA, Jones CM. Trends in opioid analgesic-prescribing rates by specialty, U.S., 2007-2012. Am J Prev Med. 2015;49(3):409–413.CrossRefPubMedPubMedCentral Levy B, Paulozzi L, Mack KA, Jones CM. Trends in opioid analgesic-prescribing rates by specialty, U.S., 2007-2012. Am J Prev Med. 2015;49(3):409–413.CrossRefPubMedPubMedCentral
13.
14.
go back to reference Lee JS, Hu HM, Edelman AL, et al. New persistent opioid use among patients with Cancer after curative-intent surgery. J Clin Oncol. 2017;35(36):4042–4049.CrossRefPubMed Lee JS, Hu HM, Edelman AL, et al. New persistent opioid use among patients with Cancer after curative-intent surgery. J Clin Oncol. 2017;35(36):4042–4049.CrossRefPubMed
15.
go back to reference Porucznik CA, Johnson EM, Rolfs RT, Sauer BC. Specialty of prescribers associated with prescription opioid fatalities in Utah, 2002-2010. Pain Med. 2014;15(1):73–78.CrossRefPubMed Porucznik CA, Johnson EM, Rolfs RT, Sauer BC. Specialty of prescribers associated with prescription opioid fatalities in Utah, 2002-2010. Pain Med. 2014;15(1):73–78.CrossRefPubMed
16.
go back to reference Brat GA, Agniel D, Beam A, et al. Postsurgical prescriptions for opioid naive patients and association with overdose and misuse: retrospective cohort study. BMJ. 2018;360:j5790.CrossRefPubMedPubMedCentral Brat GA, Agniel D, Beam A, et al. Postsurgical prescriptions for opioid naive patients and association with overdose and misuse: retrospective cohort study. BMJ. 2018;360:j5790.CrossRefPubMedPubMedCentral
17.
go back to reference Bohnert AS, Valenstein M, Bair MJ, et al. Association between opioid prescribing patterns and opioid overdose-related deaths. JAMA. 2011;305(13):1315–1321.CrossRefPubMed Bohnert AS, Valenstein M, Bair MJ, et al. Association between opioid prescribing patterns and opioid overdose-related deaths. JAMA. 2011;305(13):1315–1321.CrossRefPubMed
18.
go back to reference Leider HL, Dhaliwal J, Davis EJ, Kulakodlu M, Buikema AR. Healthcare costs and nonadherence among chronic opioid users. Am J Manag Care. 2011;17(1):32–40.PubMed Leider HL, Dhaliwal J, Davis EJ, Kulakodlu M, Buikema AR. Healthcare costs and nonadherence among chronic opioid users. Am J Manag Care. 2011;17(1):32–40.PubMed
19.
go back to reference Ray WA, Chung CP, Murray KT, Hall K, Stein CM. Prescription of long-acting opioids and mortality in patients with chronic noncancer pain. JAMA. 2016;315(22):2415–2423.CrossRefPubMedPubMedCentral Ray WA, Chung CP, Murray KT, Hall K, Stein CM. Prescription of long-acting opioids and mortality in patients with chronic noncancer pain. JAMA. 2016;315(22):2415–2423.CrossRefPubMedPubMedCentral
20.
go back to reference Ho D, Imai K, King G, Stuart EA. MatchIt: nonparametric preprocessing for parametric causal inference. J Stat Softw. 2011;42(8):28.CrossRef Ho D, Imai K, King G, Stuart EA. MatchIt: nonparametric preprocessing for parametric causal inference. J Stat Softw. 2011;42(8):28.CrossRef
21.
go back to reference Eaton LH, Gordon DB, Wyant S, et al. Development and implementation of a telehealth-enhanced intervention for pain and symptom management. Contemp Clin Trials. 2014;38(2):213–220.CrossRefPubMedPubMedCentral Eaton LH, Gordon DB, Wyant S, et al. Development and implementation of a telehealth-enhanced intervention for pain and symptom management. Contemp Clin Trials. 2014;38(2):213–220.CrossRefPubMedPubMedCentral
22.
go back to reference Penney LS, Ritenbaugh C, DeBar LL, Elder C, Deyo RA. Provider and patient perspectives on opioids and alternative treatments for managing chronic pain: a qualitative study. BMC Fam Pract. 2017;17(1):164.CrossRefPubMedPubMedCentral Penney LS, Ritenbaugh C, DeBar LL, Elder C, Deyo RA. Provider and patient perspectives on opioids and alternative treatments for managing chronic pain: a qualitative study. BMC Fam Pract. 2017;17(1):164.CrossRefPubMedPubMedCentral
23.
go back to reference Frank JW, Levy C, Matlock DD, et al. Patients’ perspectives on tapering of chronic opioid therapy: a qualitative study. Pain Med. 2016;17(10):1838–1847.CrossRefPubMed Frank JW, Levy C, Matlock DD, et al. Patients’ perspectives on tapering of chronic opioid therapy: a qualitative study. Pain Med. 2016;17(10):1838–1847.CrossRefPubMed
24.
go back to reference Hao J, Lucido D, Cruciani RA. Potential impact of abrupt opioid therapy discontinuation in the management of chronic pain: a pilot study on patient perspective. J Opioid Manag. 2014;10(1):9–20.CrossRefPubMed Hao J, Lucido D, Cruciani RA. Potential impact of abrupt opioid therapy discontinuation in the management of chronic pain: a pilot study on patient perspective. J Opioid Manag. 2014;10(1):9–20.CrossRefPubMed
25.
26.
go back to reference Hill MV, Stucke RS, McMahon ML, Beeman JL, Barth RJ, Jr. An educational intervention decreases opioid prescribing after general surgical operations. Ann Surg. 2017. Hill MV, Stucke RS, McMahon ML, Beeman JL, Barth RJ, Jr. An educational intervention decreases opioid prescribing after general surgical operations. Ann Surg. 2017.
27.
go back to reference Hah JM, Bateman BT, Ratliff J, Curtin C, Sun E. Chronic opioid use after surgery: implications for perioperative management in the face of the opioid epidemic. Anesth Analg. 2017;125(5):1733–1740.CrossRefPubMed Hah JM, Bateman BT, Ratliff J, Curtin C, Sun E. Chronic opioid use after surgery: implications for perioperative management in the face of the opioid epidemic. Anesth Analg. 2017;125(5):1733–1740.CrossRefPubMed
28.
go back to reference Kumar K, Kirksey MA, Duong S, Wu CL. A review of opioid-sparing modalities in perioperative pain management: methods to decrease opioid use postoperatively. Anesth Analg. 2017;125(5):1749–1760.CrossRefPubMed Kumar K, Kirksey MA, Duong S, Wu CL. A review of opioid-sparing modalities in perioperative pain management: methods to decrease opioid use postoperatively. Anesth Analg. 2017;125(5):1749–1760.CrossRefPubMed
29.
go back to reference Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain—United States, 2016. JAMA. 2016;315(15):1624–1645.CrossRefPubMed Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain—United States, 2016. JAMA. 2016;315(15):1624–1645.CrossRefPubMed
30.
go back to reference Cifuentes M, Powell R, Webster B. Shorter time between opioid prescriptions associated with reduced work disability among acute low back pain opioid users. J Occup Environ Med. 2012;54(4):491–496.CrossRefPubMed Cifuentes M, Powell R, Webster B. Shorter time between opioid prescriptions associated with reduced work disability among acute low back pain opioid users. J Occup Environ Med. 2012;54(4):491–496.CrossRefPubMed
31.
go back to reference Thomas DA, Chang D, Zhu R, Rayaz H, Vadivelu N. Concept of the ambulatory pain physician. Curr Pain Headache Rep. 2017;21(1):7.CrossRefPubMed Thomas DA, Chang D, Zhu R, Rayaz H, Vadivelu N. Concept of the ambulatory pain physician. Curr Pain Headache Rep. 2017;21(1):7.CrossRefPubMed
32.
go back to reference Peppin JF, Cheatle MD, Kirsh KL, McCarberg BH. The complexity model: a novel approach to improve chronic pain care. Pain Med. 2015;16(4):653–666.CrossRefPubMed Peppin JF, Cheatle MD, Kirsh KL, McCarberg BH. The complexity model: a novel approach to improve chronic pain care. Pain Med. 2015;16(4):653–666.CrossRefPubMed
Metadata
Title
Transitions of Care for Postoperative Opioid Prescribing in Previously Opioid-Naïve Patients in the USA: a Retrospective Review
Authors
Michael P. Klueh, BS
Hsou M. Hu, PhD
Ryan A. Howard, MD
Joceline V. Vu, MD
Calista M. Harbaugh, MD
Pooja A. Lagisetty, MD
Chad M. Brummett, MD
Michael J. Englesbe, MD
Jennifer F. Waljee, MD, MPH, MS
Jay S. Lee, MD
Publication date
01-10-2018
Publisher
Springer US
Published in
Journal of General Internal Medicine / Issue 10/2018
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-018-4463-1

Other articles of this Issue 10/2018

Journal of General Internal Medicine 10/2018 Go to the issue

Concise Research Reports

Words Matter