A 59-year-old man with rheumatoid arthritis on long-term methotrexate presented with 6 months of multiple painful lesions on his heels that impaired his gait. He denied any trauma to his foot or new medications. Physical examination revealed multiple painful papules and nodules on his heels (Fig.1). A skin biopsy of a nodule showed diffuse interstitial and granulomatous infiltration throughout the dermis, with a central area of necrosis surrounded by palisading epithelioid macrophages (Fig.2), findings consistent with rheumatoid nodules (RN).
WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.