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Published in: Journal of General Internal Medicine 11/2016

01-11-2016 | Original Research

Differential Impact of Homelessness on Glycemic Control in Veterans with Type 2 Diabetes Mellitus

Authors: R. Neal Axon, MD, MSCR, Mulugeta Gebregziabher, PhD, Clara E. Dismuke, PhD, Kelly J. Hunt, PhD, Derik Yeager, MPH, Elizabeth J. Santa Ana, PhD, Leonard E. Egede, MD, MS

Published in: Journal of General Internal Medicine | Issue 11/2016

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ABSTRACT

BACKGROUND

Veterans with evidence of homelessness have high rates of mental health and substance abuse disorders, but chronic medical conditions such as diabetes are also prevalent.

OBJECTIVE

We aimed to determine the impact of homelessness on glycemic control in patients with type 2 diabetes mellitus.

DESIGN

Longitudinal analysis of a retrospective cohort.

SUBJECTS

A national cohort of 1,263,906 Veterans with type 2 diabetes. Subjects with evidence of homelessness were identified using a combination of diagnostic and administrative codes.

MAIN MEASURES

Odds for poor glycemic control using hemoglobin A1C (HbA1C) cutoff values of 8 % and 9 %. Homeless defined as a score based on the number of indicator variables for homelessness within a veterans chart.

KEY RESULTS

Veterans with evidence of homelessness had a significantly greater annual mean HbA1C ≥ 8 (32.6 % vs. 20.43 %) and HbA1C ≥ 9 (21.4 % vs. 9.9 %), tended to be younger (58 vs. 67 years), were more likely to be non-Hispanic black (39.1 %), divorced (43 %) or never married (34 %), to be urban dwelling (88.8 %), and to have comorbid substance abuse (46.7 %), depression (42.3 %), psychoses (39.7 %), liver disease (18.8 %), and fluid/electrolyte disorders (20.4 %), relative to non-homeless veterans (all p < 0.0001). Homelessness was modeled as an ordinal variable that scored the number of times a homelessness indicator was found in the Veterans medical record. We observed a significant interaction between homelessness and race/ethnicity on the odds of poor glycemic control. Homelessness, across all racial-ethnic groups, was associated with increased odds of uncontrolled diabetes at a cut-point of 8 % and 9 % for hemoglobin A1C ; however, the magnitude of the association was greater in non-Hispanic whites [8 %, OR 1.55 (1.47;1.63)] and Hispanics [8 %, OR 2.11 (1.78;2.51)] than in non-Hispanic blacks [8 %, OR 1.22 (1.15;1.28)].

CONCLUSIONS

Homelessness is a significant risk factor for uncontrolled diabetes in Veterans, especially among non-Hispanic white and Hispanic patients. While efforts to engage homeless patients in primary care services have had some success in recent years, these data suggest that broader efforts targeting management of diabetes and other chronic medical conditions remain warranted.
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Metadata
Title
Differential Impact of Homelessness on Glycemic Control in Veterans with Type 2 Diabetes Mellitus
Authors
R. Neal Axon, MD, MSCR
Mulugeta Gebregziabher, PhD
Clara E. Dismuke, PhD
Kelly J. Hunt, PhD
Derik Yeager, MPH
Elizabeth J. Santa Ana, PhD
Leonard E. Egede, MD, MS
Publication date
01-11-2016
Publisher
Springer US
Published in
Journal of General Internal Medicine / Issue 11/2016
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-016-3786-z

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