Published in:
01-01-2017 | Clinical Practice: Clinical Images
Minocycline-induced Hyperpigmentation
Published in: Journal of General Internal Medicine | Issue 1/2017
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A 76-year-old man presented with areas of progressive skin darkening for 2 years. On exam, he had hyper-pigmented, non-blanching coalescent macules on his arms, legs, and abdomen (Figs. 1 and 2). They were painless and non-pruritic. He had been taking minocycline as suppressive therapy for an infection that complicated a C3–C7 laminectomy and posterior fusion 27 months earlier. He was diagnosed with minocycline-induced hyperpigmentation (MIH).
Figure 1
Hyperpigmented macules on the lower extremities.
Figure 2
Hyperpigmented macules on the upper extremities.
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