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Journal of General Internal Medicine
Published in: Journal of General Internal Medicine 2/2016

01-02-2016 | Capsule Commentary

Capsule Commentary on Peltz-Sinvani et al., Low ALT Levels Independently Associated with 22-Year All-Cause Mortality among Coronary Heart Disease Patients

Author: Kirk V. Shepard II, MD

Published in: Journal of General Internal Medicine | Issue 2/2016

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Excerpt

Low ALT has been associated with frailty and mortality in other populations. In this study, Peltz-Sinvani et al.1 assessed the association between low ALT (<17 IU/L) blood levels and long-term (22.8 years) all-cause mortality in patients with stable coronary heart disease. The authors used the Bezafibrate Infarction Prevention (BIP) registry population, which contains over 15,000 patients 40 to 74 years of age with stable coronary heart disease who have been followed continuously for over two decades.2 In their analysis they excluded patients with elevated ALTs. …
Literature
1.
2.
Goldbourt U, et al. Rationale and design of a secondary prevention trial of increasing serum high-density lipoprotein cholesterol and reducing triglycerides in patients with clinically manifest atherosclerotic heart disease (the Bezafibrate Infarction Prevention Trial). Am J Cardiol. 1993;71(11):909–15.CrossRefPubMed
Metadata
Title
Capsule Commentary on Peltz-Sinvani et al., Low ALT Levels Independently Associated with 22-Year All-Cause Mortality among Coronary Heart Disease Patients
Author
Kirk V. Shepard II, MD
Publication date
01-02-2016
Publisher
Springer US
Published in
Journal of General Internal Medicine / Issue 2/2016
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-015-3544-7

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