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Published in: Journal of General Internal Medicine 9/2011

01-09-2011 | Health Policy

Artificial Nutrition and Hydration: The Evolution of Ethics, Evidence, and Policy

Authors: Howard Brody, MD, PhD, Laura D. Hermer, JD, LLM, Larry D. Scott, MD, MA, L. Lee Grumbles, MD, Julie E. Kutac, MA, Susan D. McCammon, MD

Published in: Journal of General Internal Medicine | Issue 9/2011

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Abstract

Introduction

The debate over use of artificial nutrition and hydration (ANH) in terminal illness, including advanced dementia, remains contentious despite extensive ethical and empirical investigation.

Methods

For this narrative review we undertook a focused, selective review of literature reflecting ethical analysis, empirical assessment of outcomes, legal responses, and thinking within the Roman Catholic religious tradition.

Results

The history of the debate over the past 60 years results from a complex interplay of ethical concerns, a growing empirical database, legal changes, public opinion, and financial as well as institutional concerns. Discussions of ANH today are often conducted without any understanding of this historical context.

Discussion

Patients’ interests could be better protected through remedial action at both the individual and the policy levels.
Literature
1.
go back to reference Mitchell SL, Teno JM, Roy J, et al. Clinical and organizational factors associated with feeding tube use among nursing home residents with advanced cognitive impairment. JAMA. 2003;290:73–80.PubMedCrossRef Mitchell SL, Teno JM, Roy J, et al. Clinical and organizational factors associated with feeding tube use among nursing home residents with advanced cognitive impairment. JAMA. 2003;290:73–80.PubMedCrossRef
2.
go back to reference Mitchell SL, Kiely DK, Hamel MB. Dying with advanced dementia in the nursing home. Arch Intern Med. 2004;164:321–26.PubMedCrossRef Mitchell SL, Kiely DK, Hamel MB. Dying with advanced dementia in the nursing home. Arch Intern Med. 2004;164:321–26.PubMedCrossRef
3.
go back to reference Mitchell SL, Teno JM, Kiely DK, et al. The clinical course of advanced dementia. N Engl J Med. 2009;361:1529–38.PubMedCrossRef Mitchell SL, Teno JM, Kiely DK, et al. The clinical course of advanced dementia. N Engl J Med. 2009;361:1529–38.PubMedCrossRef
4.
go back to reference Teno JM, Mitchell SL, Gozalo PL, et al. Hospital characteristics associated with feeding tube placement in nursing home residents with advanced cognitive impairment. JAMA. 2010;303:544–550.PubMedCrossRef Teno JM, Mitchell SL, Gozalo PL, et al. Hospital characteristics associated with feeding tube placement in nursing home residents with advanced cognitive impairment. JAMA. 2010;303:544–550.PubMedCrossRef
5.
go back to reference Sampson EL, Candy B, Jones L. Enteral tube feeding for older people with advanced dementia. Cochrane Database Syst Rev 2009 Apr 15; (2):CD007209. Sampson EL, Candy B, Jones L. Enteral tube feeding for older people with advanced dementia. Cochrane Database Syst Rev 2009 Apr 15; (2):CD007209.
6.
go back to reference Howland JS. A defense of assisted nutrition and hydration in patients with dementia. Natl Cathol Bioeth Q. 2009;9:697–710. Howland JS. A defense of assisted nutrition and hydration in patients with dementia. Natl Cathol Bioeth Q. 2009;9:697–710.
8.
go back to reference American Academy of Hospice and Palliative Medicine. Statement on artificial nutrition and hydration at the end of life. December 2006. American Academy of Hospice and Palliative Medicine. Statement on artificial nutrition and hydration at the end of life. December 2006.
11.
12.
go back to reference Annas GJ. “Culture of life” politics at the bedside: the case of Terri Schiavo. N Engl J Med. 2005;352:1710–15.PubMedCrossRef Annas GJ. “Culture of life” politics at the bedside: the case of Terri Schiavo. N Engl J Med. 2005;352:1710–15.PubMedCrossRef
13.
14.
go back to reference Pius XII. The prolongation of life: allocution to the international congress of anesthesiologists. Pope Speaks. 1958;4:393–97. Pius XII. The prolongation of life: allocution to the international congress of anesthesiologists. Pope Speaks. 1958;4:393–97.
15.
go back to reference Drane JF. Stopping nutrition and hydration technologies: a conflict between traditional Catholic ethics and church authority. Christian Bioethics. 2006;12:11–28.PubMedCrossRef Drane JF. Stopping nutrition and hydration technologies: a conflict between traditional Catholic ethics and church authority. Christian Bioethics. 2006;12:11–28.PubMedCrossRef
16.
go back to reference Kelly G. The duty of using artificial means of preserving life. Theological Studies. 1950;11:203–20. Kelly G. The duty of using artificial means of preserving life. Theological Studies. 1950;11:203–20.
17.
go back to reference President’s Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. Deciding to forgo life-sustaining treatment. Washington, DC: US Government Printing Office; 1983. President’s Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. Deciding to forgo life-sustaining treatment. Washington, DC: US Government Printing Office; 1983.
18.
go back to reference Lynn J, ed. By no extraordinary means: the choice to forgo life-sustaining food and water. Bloomington: Indiana University Press; 1986. Lynn J, ed. By no extraordinary means: the choice to forgo life-sustaining food and water. Bloomington: Indiana University Press; 1986.
19.
go back to reference Siegler M, Weisbard AJ. Against the emerging stream: should fluids and nutritional support be discontinued? Arch Intern Med. 1985;145:129–31.PubMedCrossRef Siegler M, Weisbard AJ. Against the emerging stream: should fluids and nutritional support be discontinued? Arch Intern Med. 1985;145:129–31.PubMedCrossRef
20.
21.
go back to reference Hastings Center. Guidelines on the termination of life-sustaining treatment and the care of the dying. Briarcliff Manor: Hastings Center; 1987. Hastings Center. Guidelines on the termination of life-sustaining treatment and the care of the dying. Briarcliff Manor: Hastings Center; 1987.
22.
go back to reference Lo B, Dornbrand L. Understanding the benefits and burdens of tube feedings. Arch Intern Med. 1989;149:1925–26.PubMedCrossRef Lo B, Dornbrand L. Understanding the benefits and burdens of tube feedings. Arch Intern Med. 1989;149:1925–26.PubMedCrossRef
23.
24.
go back to reference Nat’l Conf. of Comm’rs of Unif. State Laws. Uniform Rights of the Terminally Ill Act, § 6 (1989). Nat’l Conf. of Comm’rs of Unif. State Laws. Uniform Rights of the Terminally Ill Act, § 6 (1989).
26.
go back to reference Nat’l Conf. of Comm’rs of Unif. State Laws. Unif. Health-Care Decisions Act. §§ 1, 2, 5, 6 (1993). Nat’l Conf. of Comm’rs of Unif. State Laws. Unif. Health-Care Decisions Act. §§ 1, 2, 5, 6 (1993).
27.
go back to reference Longenecker RL. Health care proxies, living wills, and durable powers of attorney. ABA-ALI Course of Study. 1991;C644:437–520. Longenecker RL. Health care proxies, living wills, and durable powers of attorney. ABA-ALI Course of Study. 1991;C644:437–520.
28.
go back to reference Finucane TE, Christmas C, Travis K. Tube feeding in patients with advanced dementia. JAMA. 1999;282:1365–70.PubMedCrossRef Finucane TE, Christmas C, Travis K. Tube feeding in patients with advanced dementia. JAMA. 1999;282:1365–70.PubMedCrossRef
29.
go back to reference Gillick MR. Rethinking the role of tube feeding in patients with advanced dementia. N Engl J Med. 2000;342:206–10.PubMedCrossRef Gillick MR. Rethinking the role of tube feeding in patients with advanced dementia. N Engl J Med. 2000;342:206–10.PubMedCrossRef
30.
go back to reference Sanders DS, Carter MJ, D’Silva J, et al. Survival analysis in percutaneous endoscopic gastrostomy feeding: a worse outcome in patients with dementia. Am J Gastroenterol. 2000;95:1472–75.PubMedCrossRef Sanders DS, Carter MJ, D’Silva J, et al. Survival analysis in percutaneous endoscopic gastrostomy feeding: a worse outcome in patients with dementia. Am J Gastroenterol. 2000;95:1472–75.PubMedCrossRef
31.
go back to reference Garrow D, Pride P, William M, et al. Feeding alternatives in patients with dementia: examining the evidence. Clin Gastroenterol Hepatol. 2007;5:1372–78.PubMedCrossRef Garrow D, Pride P, William M, et al. Feeding alternatives in patients with dementia: examining the evidence. Clin Gastroenterol Hepatol. 2007;5:1372–78.PubMedCrossRef
32.
go back to reference Ganzini L. Artificial nutrition and hydration at the end of life: ethics and evidence. Palliat Support Care. 2006;4:135–43.PubMedCrossRef Ganzini L. Artificial nutrition and hydration at the end of life: ethics and evidence. Palliat Support Care. 2006;4:135–43.PubMedCrossRef
33.
go back to reference Dy SM. Enteral and parenteral nutrition in terminally ill cancer patients: a review of the literature. Am J Hosp Palliat Care. 2006;23:369–77.PubMedCrossRef Dy SM. Enteral and parenteral nutrition in terminally ill cancer patients: a review of the literature. Am J Hosp Palliat Care. 2006;23:369–77.PubMedCrossRef
34.
go back to reference Murphy LM, Lipman TO. Percutaneous endoscopic gastrostomy does not prolong survival in patients with dementia. Arch Intern Med. 2003;163:1351–53.PubMedCrossRef Murphy LM, Lipman TO. Percutaneous endoscopic gastrostomy does not prolong survival in patients with dementia. Arch Intern Med. 2003;163:1351–53.PubMedCrossRef
35.
go back to reference Cervo FA, Bryan L, Farber S. To PEG or not to PEG: a review of evidence for placing feeding tubes in advanced dementia and the decision-making process. Geriatrics. 2006;61:30–35.PubMed Cervo FA, Bryan L, Farber S. To PEG or not to PEG: a review of evidence for placing feeding tubes in advanced dementia and the decision-making process. Geriatrics. 2006;61:30–35.PubMed
36.
37.
go back to reference Casarett D, Kapo J, Caplan A. Appropriate use of artificial nutrition and hydration—fundamental principles and recommendations. N Engl J Med. 2005;353:2607–12.PubMedCrossRef Casarett D, Kapo J, Caplan A. Appropriate use of artificial nutrition and hydration—fundamental principles and recommendations. N Engl J Med. 2005;353:2607–12.PubMedCrossRef
39.
40.
go back to reference Schmitz P. The process of dying with and without feeding and fluids by tube. Law Med Health Care. 1991;19:23–26.PubMed Schmitz P. The process of dying with and without feeding and fluids by tube. Law Med Health Care. 1991;19:23–26.PubMed
41.
go back to reference Printz LA. Is withdrawing hydration a valid comfort measure in the terminally ill? Geriatrics. 1988;43:84–88.PubMed Printz LA. Is withdrawing hydration a valid comfort measure in the terminally ill? Geriatrics. 1988;43:84–88.PubMed
42.
43.
go back to reference Smith SA, Andrews M. Artificial nutrition and hydration at the end of life. Medsurg Nurs. 2000;9:233–44.PubMed Smith SA, Andrews M. Artificial nutrition and hydration at the end of life. Medsurg Nurs. 2000;9:233–44.PubMed
44.
45.
go back to reference Yarborough M. Why physicians must not give food and water to every patient. J Fam Pract. 1989;29:683–84.PubMed Yarborough M. Why physicians must not give food and water to every patient. J Fam Pract. 1989;29:683–84.PubMed
46.
go back to reference Callahan CM, Haag KM, Buchanan NN, Nisi R. Decision-making for percutaneous endoscopic gastrostomy among older adults in a community setting. J Am Geriatr Soc. 1999;47:1105–09.PubMed Callahan CM, Haag KM, Buchanan NN, Nisi R. Decision-making for percutaneous endoscopic gastrostomy among older adults in a community setting. J Am Geriatr Soc. 1999;47:1105–09.PubMed
47.
go back to reference Monturo CA, Strumpf NE. Advance directives at end-of-life: nursing home resident preferences for artificial nutrition. J Am Med Dir Assoc. 2007;8:224–28.PubMedCrossRef Monturo CA, Strumpf NE. Advance directives at end-of-life: nursing home resident preferences for artificial nutrition. J Am Med Dir Assoc. 2007;8:224–28.PubMedCrossRef
48.
go back to reference Schrader SL, Nelson ML, Eidsness LM. “South Dakota’s dying to know”: a statewide survey about end of life. J Palliat Med. 2009;12:695–705.PubMedCrossRef Schrader SL, Nelson ML, Eidsness LM. “South Dakota’s dying to know”: a statewide survey about end of life. J Palliat Med. 2009;12:695–705.PubMedCrossRef
49.
go back to reference Shega JW, Hougham GW, Stocking CB, Sachs GA. Barriers to limiting the practice of feeding tube placement in advanced dementia. J Palliat Med. 2003;6:885–93.PubMedCrossRef Shega JW, Hougham GW, Stocking CB, Sachs GA. Barriers to limiting the practice of feeding tube placement in advanced dementia. J Palliat Med. 2003;6:885–93.PubMedCrossRef
50.
go back to reference Vitale CA, Hiner T, Ury WA, et al. Tube feeding in advanced dementia: an exploratory survey of physician knowledge. Care Manag J. 2006;7:79–85.PubMedCrossRef Vitale CA, Hiner T, Ury WA, et al. Tube feeding in advanced dementia: an exploratory survey of physician knowledge. Care Manag J. 2006;7:79–85.PubMedCrossRef
51.
go back to reference Monteleoni C, Clark C. Using rapid-cycle quality improvement methodology to reduce feeding tubes in patients with advanced dementia: before and after study. BMJ. 2004;239:491–94.CrossRef Monteleoni C, Clark C. Using rapid-cycle quality improvement methodology to reduce feeding tubes in patients with advanced dementia: before and after study. BMJ. 2004;239:491–94.CrossRef
52.
go back to reference Smith WJ. Culture of death: the assault on medical ethics in America. San Francisco: Encounter Books, 2000. Smith WJ. Culture of death: the assault on medical ethics in America. San Francisco: Encounter Books, 2000.
53.
54.
go back to reference N. Dakota Cen. Code § 23–06.5-09(6) (West 2009). N. Dakota Cen. Code § 23–06.5-09(6) (West 2009).
55.
go back to reference NY Public Health Act § 2982(2) (West 2009). NY Public Health Act § 2982(2) (West 2009).
56.
go back to reference NY Surrogate Court Procedure Act § 1750b(b)(iii) (West 2009). NY Surrogate Court Procedure Act § 1750b(b)(iii) (West 2009).
61.
go back to reference 20 Pa. C.S.A. § 5456(c)(5)(iii) (West 2009). 20 Pa. C.S.A. § 5456(c)(5)(iii) (West 2009).
62.
63.
go back to reference Stolberg SG. The Schiavo case: the legacy; a collision of disparate forces may be reshaping American law. New York Times, April 1, 2005:A18. Stolberg SG. The Schiavo case: the legacy; a collision of disparate forces may be reshaping American law. New York Times, April 1, 2005:A18.
64.
65.
70.
go back to reference Swartz MS. “Conscience clauses” or “unconscionable clauses”: personal beliefs vs. professional responsibilities. Yale J Health Policy Law Ethics. 2006;6:269–350.PubMed Swartz MS. “Conscience clauses” or “unconscionable clauses”: personal beliefs vs. professional responsibilities. Yale J Health Policy Law Ethics. 2006;6:269–350.PubMed
71.
go back to reference Pope TM. Medical futility statutes: no safe harbor to unilaterally refuse life-sustaining treatment. Tenn L Rev. 2007;75:1–81. Pope TM. Medical futility statutes: no safe harbor to unilaterally refuse life-sustaining treatment. Tenn L Rev. 2007;75:1–81.
72.
go back to reference 42 USC 300a-7(d) (West 2010); 45 CFR 88.4(d) (West 2010). 42 USC 300a-7(d) (West 2010); 45 CFR 88.4(d) (West 2010).
73.
74.
go back to reference Miss. Code § 41-107-5(1) & (2) (West 2009). Miss. Code § 41-107-5(1) & (2) (West 2009).
75.
go back to reference 745 Ill. Comp. Stat. §§ 70/4, 70/5 70/7, 70/9, 70/14 (West 2009). 745 Ill. Comp. Stat. §§ 70/4, 70/5 70/7, 70/9, 70/14 (West 2009).
76.
go back to reference Shannon TA, Walter JJ. Implications of the papal allocution on feeding tubes. Hastings Cent Rep. 2004;34:18–20.PubMed Shannon TA, Walter JJ. Implications of the papal allocution on feeding tubes. Hastings Cent Rep. 2004;34:18–20.PubMed
79.
go back to reference Consortium of Jesuit Bioethics Programs. Undue burden? The Vatican and artificial nutrition and hydration. Commonweal. 2009;136:13–15. Consortium of Jesuit Bioethics Programs. Undue burden? The Vatican and artificial nutrition and hydration. Commonweal. 2009;136:13–15.
80.
go back to reference Bradley CT. Roman Catholic doctrine guiding end-of-life care: a summary of the recent discourse. J Palliat Med. 2009;12:373–77.PubMedCrossRef Bradley CT. Roman Catholic doctrine guiding end-of-life care: a summary of the recent discourse. J Palliat Med. 2009;12:373–77.PubMedCrossRef
82.
go back to reference Sanders A. The clinical reality of artificial nutrition and hydration for patients at the end of life. Natl Cathol Bioeth Quart. 2009;9:293–304. Sanders A. The clinical reality of artificial nutrition and hydration for patients at the end of life. Natl Cathol Bioeth Quart. 2009;9:293–304.
83.
go back to reference Graham RC. Decisions about CPR [letter]. N Engl J Med. 1988;318:1273. Graham RC. Decisions about CPR [letter]. N Engl J Med. 1988;318:1273.
84.
go back to reference Palecek EJ, Teno JM, Casarett DJ, et al. Comfort feeding only: a proposal to bring clarity to decision-making regarding difficulty with eating for persons with advanced dementia. J Am Geriatr Soc. 2010;58:580–84.PubMedCrossRef Palecek EJ, Teno JM, Casarett DJ, et al. Comfort feeding only: a proposal to bring clarity to decision-making regarding difficulty with eating for persons with advanced dementia. J Am Geriatr Soc. 2010;58:580–84.PubMedCrossRef
86.
Metadata
Title
Artificial Nutrition and Hydration: The Evolution of Ethics, Evidence, and Policy
Authors
Howard Brody, MD, PhD
Laura D. Hermer, JD, LLM
Larry D. Scott, MD, MA
L. Lee Grumbles, MD
Julie E. Kutac, MA
Susan D. McCammon, MD
Publication date
01-09-2011
Publisher
Springer-Verlag
Published in
Journal of General Internal Medicine / Issue 9/2011
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-011-1659-z

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