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Published in: Journal of General Internal Medicine 12/2008

01-12-2008 | Original Article

How Often is Dizziness from Primary Cardiovascular Disease True Vertigo? A Systematic Review

Authors: David E. Newman-Toker, MD, PhD, Fei Jamie Dy, MSc, Victoria A. Stanton, BA, David S. Zee, MD, Hugh Calkins, MD, Karen A. Robinson, MSc

Published in: Journal of General Internal Medicine | Issue 12/2008

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Abstract

Objectives

To assess how frequently cardiovascular dizziness is vertigo. Recent studies suggest providers do not consider cardiovascular causes when a patient reports true vertigo (spinning/motion) as opposed to presyncope (impending faint). It is known that cardiovascular disease causes dizziness, but unknown how often such dizziness is vertiginous, as opposed to presyncopal.

Data Sources

Systematic review of observational studies was made: Search—electronic (MEDLINE, EMBASE) and manual (references of eligible articles) search for English-language studies (1972–2007).

Review Methods

Inclusions Studies of ≥5 patients with confirmed cardiovascular causes for dizziness and reporting a proportion with vertigo were included. Two independent reviewers selected studies for inclusion, with differences adjudicated by a third. Study characteristics and dizziness-type proportions were abstracted. Studies were rated on methodology and quality of dizziness definitions. Differences were resolved by consensus.

Results

We identified 1,506 citations, examined 125 full manuscripts, and included 5 studies. Principal reasons for exclusion were: abstracts—lack of original data, no cardiovascular diagnosis, or confounding exposure/disease (74%); manuscripts—failure to distinguish vertigo from other dizziness types (78%). In the three studies not using vertigo as an entry criterion (representing 1,659 patients with myocardial infarction, orthostatic hypotension, or syncope), vertigo was present in 63% (95% CI 57–69%) of cardiovascular patients with dizziness and the only dizziness type in 37% (95% CI 31–43%). Limitations include modest study quality and non-uniform definitions for vertigo.

Conclusions

Published data suggest that dizziness from primary cardiovascular disease may often be vertigo. Future research should assess prospectively whether dizziness type is a meaningful predictor for or against a cardiovascular diagnosis.
Appendix
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Metadata
Title
How Often is Dizziness from Primary Cardiovascular Disease True Vertigo? A Systematic Review
Authors
David E. Newman-Toker, MD, PhD
Fei Jamie Dy, MSc
Victoria A. Stanton, BA
David S. Zee, MD
Hugh Calkins, MD
Karen A. Robinson, MSc
Publication date
01-12-2008
Publisher
Springer-Verlag
Published in
Journal of General Internal Medicine / Issue 12/2008
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-008-0801-z

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