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Journal of Gastrointestinal Surgery

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01-07-2013 | Original Article

Pancreatic Surgery with Vascular Reconstruction in Patients with Locally Advanced Pancreatic Neuroendocrine Tumors

Authors: Sven-Petter Haugvik, Knut Jørgen Labori, Anne Waage, Pål-Dag Line, Øystein Mathisen, Ivar Prydz Gladhaug

Published in: Journal of Gastrointestinal Surgery | Issue 7/2013

Abstract

Introduction

Pancreatic neuroendocrine tumors (PNET) are rare neoplasms with better prognosis than most pancreatic malignancies. Surgery of locally advanced PNET remains controversial, and the role of vascular reconstruction in this patient group has yet to be defined. The aim of this study was to evaluate the feasibility and outcome of pancreatic resections with vascular reconstruction in patients with locally advanced PNET.

Methods

Retrospective analysis of patients who underwent pancreatic surgery with vascular reconstruction for locally advanced PNET at a single institution. Furthermore, a review of the relevant literature on the topic was performed.

Results

Seven patients who had undergone vascular reconstruction for locally advanced PNET were identified. Four patients had liver metastases at time of surgery. Postoperative complications developed in four patients with no mortality. Median follow-up time of all patients was 21 (range, 3–58) months. Three patients had disease in remission after 58, 42 and 3 months, respectively. One patient died 35 months postoperatively due to progressive disease, whereas three patients had progression of disease after 21, 9, and 4 months postoperatively.

Conclusion

Pancreatic surgery with vascular reconstruction in patients with locally advanced PNET is feasible with acceptable outcome.

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Title: Pancreatic Surgery with Vascular Reconstruction in Patients with Locally Advanced Pancreatic Neuroendocrine Tumors
Authors: Sven-Petter Haugvik
Knut Jørgen Labori
Anne Waage
Pål-Dag Line
Øystein Mathisen
Ivar Prydz Gladhaug
Publication date: 01-07-2013
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 7/2013
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-013-2221-6

At a glance: The STEP trials

Springer Medicine

Pancreatic Surgery with Vascular Reconstruction in Patients with Locally Advanced Pancreatic Neuroendocrine Tumors

Abstract

Introduction

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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