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Journal of Gastrointestinal Surgery

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01-07-2013 | Original Article

Peroral Endoscopic Myotomy (POEM) Is Safe and Effective in the Setting of Prior Endoscopic Intervention

Authors: Ahmed Sharata, Ashwin A. Kurian, Christy M. Dunst, Neil H. Bhayani, Kevin M. Reavis, Lee L. Swanström

Published in: Journal of Gastrointestinal Surgery | Issue 7/2013

Abstract

Objective

We aimed to determine the safety and feasibility of peroral endoscopic myotomy (POEM) in the setting of prior endoscopic interventions.

Patients

This study involves 40 consecutive patients undergoing POEM.

Intervention

POEM was performed for esophageal motility disorders, including achalasia, nutcracker with nonrelaxing lower esophageal sphincter (LES), hypertensive lower esophageal sphincter, and diffuse esophageal spasm.

Main Outcome Measures

Outcome measures include length of procedure (LOP), intraoperative complications, and dysphagia relief.

Results

Forty patients, with a mean age of 54 ± 19 years, underwent POEM. The pre-POEM intervention group consisted of 12 patients (nine achalasia, two nutcracker with nonrelaxing LES, and one diffuse esophageal spasm) who also had previous endoscopic treatment, while the pre-POEM non-intervention group consisted of 28 patients (22 achalasia, 3 hypertensive LES, 2 nutcracker with nonrelaxing LES, and 1 diffuse esophageal spasm). Ten patients had botox injections and two patients had large caliber balloon dilations prior to POEM. The median preoperative Eckardt score was 5 in the pre-POEM intervention group vs 6 in the pre-POEM non-intervention group (p value = 0.4). There was no statistical difference in the mean LOP (134 ± 43 vs 131 ± 41, p = 0.8) or the incidence of intraoperative complications (17 vs 3 %, p = 0.2) between the two groups. There was also no difference in the 6-month postoperative median Eckardt scores between the two groups (1 vs 1, p = 0.4).

Conclusion

POEM is safe and effective even following preoperative endoscopic large caliber balloon dilations or botox injection. These interventions do not seem to contribute to increased adverse intraoperative or postoperative clinical outcomes.

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Title: Peroral Endoscopic Myotomy (POEM) Is Safe and Effective in the Setting of Prior Endoscopic Intervention
Authors: Ahmed Sharata
Ashwin A. Kurian
Christy M. Dunst
Neil H. Bhayani
Kevin M. Reavis
Lee L. Swanström
Publication date: 01-07-2013
Publisher: Springer-Verlag
Published in: Journal of Gastrointestinal Surgery / Issue 7/2013
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-013-2193-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Peroral Endoscopic Myotomy (POEM) Is Safe and Effective in the Setting of Prior Endoscopic Intervention

Abstract

Objective

Patients

Intervention

Main Outcome Measures

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Patients

Intervention

Main Outcome Measures

Results

Conclusion

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