Skip to main content
Top
Published in: Journal of Gastrointestinal Surgery 11/2012

01-11-2012 | Original Article

Surgical Endoscopic Vacuum Therapy for Anastomotic Leakage and Perforation of the Upper Gastrointestinal Tract

Authors: F. Kuehn, L. Schiffmann, B. M. Rau, E. Klar

Published in: Journal of Gastrointestinal Surgery | Issue 11/2012

Login to get access

Abstract

Introduction

Emergency operations for perforations and anastomotic leakage of the upper gastrointestinal tract are associated with a high overall morbidity and mortality rate. An endoscopic vacuum therapy (EVT) has been established successfully for anastomotic leakage after rectal resection but only limited data exist for EVT of the upper GI tract.

Methods

We report on a series of nine patients treated with EVT for defects of the upper intestinal tract between March 2011 and May 2012. In four patients, initial endoscopic sponge placement was performed in combination with open surgical revision. Median follow-up was 189 (range, 51–366) days.

Results

In total, 52 vacuum sponges were placed in upper GI defects of nine patients. Indication for EVT were anastomotic leakage after esophageal resection or gastrectomy (n = 5) and iatrogenic or spontaneous esophageal perforations (n = 4). The mean number of sponge insertions was six (range, 1–13) with a mean changing interval of 3.5 days (range, 2–5). A successful vacuum therapy for upper intestinal defects was achieved in eight of nine patients (89 %).

Conclusion

EVT is a promising approach for postoperative, iatrogenic, or spontaneous lesions of the upper GI tract. If necessary the endoscopic procedure can be combined with operative revision for better control of the local septic focus.
Literature
1.
go back to reference Fleischmann W, Strecker W, Bombelli M, Kinzl L. Vacuum sealing as treatment of soft tissue damage in open fractures. Unfallchirurg. 1993; 96: 488–492.PubMed Fleischmann W, Strecker W, Bombelli M, Kinzl L. Vacuum sealing as treatment of soft tissue damage in open fractures. Unfallchirurg. 1993; 96: 488–492.PubMed
2.
go back to reference Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997; 38: 563–576;PubMedCrossRef Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997; 38: 563–576;PubMedCrossRef
3.
go back to reference Weidenhagen R, Gruetzner KU, Wiecken T, Spelsberg F, Jauch KW. Endoscopic vacuum-assisted closure of anastomotic leakage following anterior resection of the rectum: a new method. Surg Endosc. 2008; 22:1818–1825.PubMedCrossRef Weidenhagen R, Gruetzner KU, Wiecken T, Spelsberg F, Jauch KW. Endoscopic vacuum-assisted closure of anastomotic leakage following anterior resection of the rectum: a new method. Surg Endosc. 2008; 22:1818–1825.PubMedCrossRef
4.
go back to reference Ahrens M, Schulte T, Egberts J, Schafmayer C, Hampe J, Fritscher-Ravens A, Broering DC, Schniewind B. Drainage of esophageal leakage using endoscopic vacuum therapy: a prospective pilot study. Endoscopy. 2010; 42: 693–698.PubMedCrossRef Ahrens M, Schulte T, Egberts J, Schafmayer C, Hampe J, Fritscher-Ravens A, Broering DC, Schniewind B. Drainage of esophageal leakage using endoscopic vacuum therapy: a prospective pilot study. Endoscopy. 2010; 42: 693–698.PubMedCrossRef
5.
go back to reference Loske G, Schorsch T, Müller C. Intraluminal and intracavitary vacuum therapy for esophageal leakage: a new endoscopic minimally invasive approach. Endoscopy. 2011 Jun; 43: 540–544.PubMedCrossRef Loske G, Schorsch T, Müller C. Intraluminal and intracavitary vacuum therapy for esophageal leakage: a new endoscopic minimally invasive approach. Endoscopy. 2011 Jun; 43: 540–544.PubMedCrossRef
6.
go back to reference Weidenhagen R, Hartl WH, Gruetzner KU, Eichhorn ME, Spelsberg F, Jauch KW. Anastomotic leakage after esophageal resection: new treatment options by endoluminal vacuum therapy. Ann Thorac Surg. 2010; 90: 1674–1681.PubMedCrossRef Weidenhagen R, Hartl WH, Gruetzner KU, Eichhorn ME, Spelsberg F, Jauch KW. Anastomotic leakage after esophageal resection: new treatment options by endoluminal vacuum therapy. Ann Thorac Surg. 2010; 90: 1674–1681.PubMedCrossRef
7.
go back to reference Huber-Lang M, Henne-Bruns D, Schmitz B, Wuerl P. Esophageal perforation: principles of diagnosis and surgical management. Surg Today. 2006; 36: 332–340.PubMedCrossRef Huber-Lang M, Henne-Bruns D, Schmitz B, Wuerl P. Esophageal perforation: principles of diagnosis and surgical management. Surg Today. 2006; 36: 332–340.PubMedCrossRef
8.
go back to reference Page RD, Shackcloth MJ, Russell GN, Pennefather SH. Surgical treatment of anastomotic leaks after oesophagectomy. Eur J Cardiothorac Surg. 2005; 27: 337–343.PubMedCrossRef Page RD, Shackcloth MJ, Russell GN, Pennefather SH. Surgical treatment of anastomotic leaks after oesophagectomy. Eur J Cardiothorac Surg. 2005; 27: 337–343.PubMedCrossRef
9.
go back to reference Tsou CC, Lo SS, Fang WL, Wu CW, Chen JH, Hsieh MC, Shen KH Risk factors and management of anastomotic leakage after radical gastrectomy for gastric cancer. Hepatogastroenterology. 2011; 58: 218–223.PubMed Tsou CC, Lo SS, Fang WL, Wu CW, Chen JH, Hsieh MC, Shen KH Risk factors and management of anastomotic leakage after radical gastrectomy for gastric cancer. Hepatogastroenterology. 2011; 58: 218–223.PubMed
10.
go back to reference Lang H, Piso P, Stukenborg C, Raab R, Jähne J. Management and results of proximal anastomotic leaks in a series of 1114 total gastrectomies for gastric carcinoma. Eur J Surg Oncol. 2000; 26:168–171.PubMedCrossRef Lang H, Piso P, Stukenborg C, Raab R, Jähne J. Management and results of proximal anastomotic leaks in a series of 1114 total gastrectomies for gastric carcinoma. Eur J Surg Oncol. 2000; 26:168–171.PubMedCrossRef
11.
go back to reference Kim RH, Takabe K. Methods of esophagogastric anastomoses following esophagectomy for cancer: A systematic review. J Surg Oncol. 2010; 101: 527–533.PubMedCrossRef Kim RH, Takabe K. Methods of esophagogastric anastomoses following esophagectomy for cancer: A systematic review. J Surg Oncol. 2010; 101: 527–533.PubMedCrossRef
12.
go back to reference Kuppusamy MK, Felisky C, Kozarek RA, Schembre D, Ross A, Gan I, Irani S, Low DE. Impact of endoscopic assessment and treatment on operative and non-operative management of acute oesophageal perforation. Br J Surg. 2011; 98: 818–824.PubMedCrossRef Kuppusamy MK, Felisky C, Kozarek RA, Schembre D, Ross A, Gan I, Irani S, Low DE. Impact of endoscopic assessment and treatment on operative and non-operative management of acute oesophageal perforation. Br J Surg. 2011; 98: 818–824.PubMedCrossRef
13.
go back to reference Doniec JM, Schniewind B, Kahlke V, Kremer B, Grimm H. Therapy of anastomotic leaks by means of covered self-expanding metallic stents after esophagogastrectomy. Endoscopy. 2003; 35: 652–658.PubMedCrossRef Doniec JM, Schniewind B, Kahlke V, Kremer B, Grimm H. Therapy of anastomotic leaks by means of covered self-expanding metallic stents after esophagogastrectomy. Endoscopy. 2003; 35: 652–658.PubMedCrossRef
14.
go back to reference Langer FB, Wenzl E, Prager G, Salat A, Miholic J, Mang T, Zacherl J. Management of postoperative esophageal leaks with the Polyflex self-expanding covered plastic stent. Ann Thorac Surg. 2005; 79: 398–403;PubMedCrossRef Langer FB, Wenzl E, Prager G, Salat A, Miholic J, Mang T, Zacherl J. Management of postoperative esophageal leaks with the Polyflex self-expanding covered plastic stent. Ann Thorac Surg. 2005; 79: 398–403;PubMedCrossRef
15.
go back to reference Shaker H, Elsayed H, Whittle I, Hussein S, Shackcloth M. The influence of the ‘golden 24-h rule’ on the prognosis of oesophageal perforation in the modern era. Eur J Cardiothorac Surg. 2010; 38: 216–222.PubMedCrossRef Shaker H, Elsayed H, Whittle I, Hussein S, Shackcloth M. The influence of the ‘golden 24-h rule’ on the prognosis of oesophageal perforation in the modern era. Eur J Cardiothorac Surg. 2010; 38: 216–222.PubMedCrossRef
16.
go back to reference Nishikawa K, Yanaga K, Kashiwagi H, Hanyuu N, Iwabuchi S. Significance of intraoperative endoscopy in total gastrectomy for gastric cancer. Surg Endosc. 2010, 10: 2633–2636.CrossRef Nishikawa K, Yanaga K, Kashiwagi H, Hanyuu N, Iwabuchi S. Significance of intraoperative endoscopy in total gastrectomy for gastric cancer. Surg Endosc. 2010, 10: 2633–2636.CrossRef
Metadata
Title
Surgical Endoscopic Vacuum Therapy for Anastomotic Leakage and Perforation of the Upper Gastrointestinal Tract
Authors
F. Kuehn
L. Schiffmann
B. M. Rau
E. Klar
Publication date
01-11-2012
Publisher
Springer-Verlag
Published in
Journal of Gastrointestinal Surgery / Issue 11/2012
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-012-2014-3

Other articles of this Issue 11/2012

Journal of Gastrointestinal Surgery 11/2012 Go to the issue