Skip to main content
Top
Published in: Journal of Gastrointestinal Surgery 11/2011

01-11-2011 | 2011 SSAT Quick Shot Presentation

Laparoscopic and Open Abdominoperineal Resection for Cancer: How Patient Selection and Complications Differ by Approach

Authors: David B. Stewart, Christopher Hollenbeak, Melissa Boltz

Published in: Journal of Gastrointestinal Surgery | Issue 11/2011

Login to get access

Abstract

Background

Outcomes between laparoscopic (LAPR) and open abdominoperineal resections (OAPR) are poorly described.

Methods

After IRB approval, 2005–2008 NSQIP data were used to identify patients undergoing LAPR and OAPR for rectal cancer. Logistic regression identified variables influencing the selection of LAPR vs. OAPR as well as the likelihood of postoperative events. Chi-square analysis was used to compare the incidence of 30-day postoperative events.

Results

One thousand one hundred ninety-seven OAPRs and 143 LAPRs were identified. LAPRs were less likely to have a body mass index (BMI) of ≥30 (p = 0.04) and were associated with equivalent mean operative times (p = 0.36). LAPRs and OAPRs were found to have similar rates of surgical site infections (p = 0.13), transfusion requirements (p = 0.17), myocardial infarction (p = 0.48), and need for reoperation within 30 days (p = 0.20). Neoadjuvant radiotherapy did not directly increase complication rates in either group. Few factors predicted choice of LAPR but included BMI <25 (OR, 1.54; p = 0.02).

Conclusion

Complication rates between LAPR and OAPR were similar despite the greater technical challenge of LAPR. Wound infection rates were equivalent, which may reflect similar rates of perineal wound infections. Few patients are offered LAPR, possibly due to surgeon preferance as opposed to patient factors.
Literature
1.
go back to reference Veldkamp R, Kuhry E, Hop WC et al. Colon cancer Laparoscopic or Open Resection Group (COLOR). Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomized trial. Lancet Oncol 2005;6(7):477–484.PubMedCrossRef Veldkamp R, Kuhry E, Hop WC et al. Colon cancer Laparoscopic or Open Resection Group (COLOR). Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomized trial. Lancet Oncol 2005;6(7):477–484.PubMedCrossRef
2.
go back to reference Guillou PJ, Quirke P, Thorpe H, et al. MRC CLASICC trial group. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomized controlled trial. Lancet 2005;365(9472):1718–1726.PubMedCrossRef Guillou PJ, Quirke P, Thorpe H, et al. MRC CLASICC trial group. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomized controlled trial. Lancet 2005;365(9472):1718–1726.PubMedCrossRef
3.
go back to reference Jayne DG, Guillou PJ, Thorpe H et al. UK MRC CLASICC Trial Group. Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin Oncol 2007;25(21):3061–3068.PubMedCrossRef Jayne DG, Guillou PJ, Thorpe H et al. UK MRC CLASICC Trial Group. Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin Oncol 2007;25(21):3061–3068.PubMedCrossRef
4.
go back to reference Jacobs M, Verdeja JC, Goldstein HS. Minimally invasive colon resection (laparoscopic colectomy). Surg Laparosc Endosc 1991;1(3):144–150.PubMed Jacobs M, Verdeja JC, Goldstein HS. Minimally invasive colon resection (laparoscopic colectomy). Surg Laparosc Endosc 1991;1(3):144–150.PubMed
5.
go back to reference Heald RJ, Karanjia ND. Results of radical surgery for rectal cancer. World J Surg 1992;16(5):848–857.PubMedCrossRef Heald RJ, Karanjia ND. Results of radical surgery for rectal cancer. World J Surg 1992;16(5):848–857.PubMedCrossRef
6.
go back to reference Pakkastie TE, Luukkonen PE, Jarvinen HJ. Anastomotic leakage after anterior resection of the rectum. Eur J Surg 1994;160(5):293–297.PubMed Pakkastie TE, Luukkonen PE, Jarvinen HJ. Anastomotic leakage after anterior resection of the rectum. Eur J Surg 1994;160(5):293–297.PubMed
7.
go back to reference Rullier E, Lauren C, Garrelo JL, Michael P, Saric J, Parneix M. Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 1998;85(3):355–358PubMedCrossRef Rullier E, Lauren C, Garrelo JL, Michael P, Saric J, Parneix M. Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 1998;85(3):355–358PubMedCrossRef
8.
go back to reference Eriksen MT, Wibe A, Norstein J, et al. Anastomotic leakage following routine mesorectal excision for rectal cancer in a national cohort of patients. Colorectal Dis 2005;7(1):51–57.PubMedCrossRef Eriksen MT, Wibe A, Norstein J, et al. Anastomotic leakage following routine mesorectal excision for rectal cancer in a national cohort of patients. Colorectal Dis 2005;7(1):51–57.PubMedCrossRef
9.
go back to reference Buie WD, MacLean AR, Attard JA, Brasher PM, Chan AK. Neoadjuvant chemoradiation increases the risk of pelvis sepsis after radical excision of rectal cancer. Dis Colon Rectum 2005;48(10):1868–74.PubMedCrossRef Buie WD, MacLean AR, Attard JA, Brasher PM, Chan AK. Neoadjuvant chemoradiation increases the risk of pelvis sepsis after radical excision of rectal cancer. Dis Colon Rectum 2005;48(10):1868–74.PubMedCrossRef
10.
go back to reference Pollard CW, Nivatvongs S, Rojanasakul A, Ilstrup DM. Carcinoma of the rectum. Profiles of intraoperative and early postoperative complications. Dis Colon Rectum 1994;37(9):866–874.PubMedCrossRef Pollard CW, Nivatvongs S, Rojanasakul A, Ilstrup DM. Carcinoma of the rectum. Profiles of intraoperative and early postoperative complications. Dis Colon Rectum 1994;37(9):866–874.PubMedCrossRef
11.
go back to reference Heald RJ. Rectal Cancer: anterior resection and local recurrence-a personal view. Perspect Colon Rectal Surg 1988;1:1–26. Heald RJ. Rectal Cancer: anterior resection and local recurrence-a personal view. Perspect Colon Rectal Surg 1988;1:1–26.
12.
go back to reference Masui H, Ike H, Yamaguchi S, et al. Male sexual function after autonomic nerve-preserving operation for rectal cancer. Dis Colon Rectum 1996;39(10):1140–1145.PubMedCrossRef Masui H, Ike H, Yamaguchi S, et al. Male sexual function after autonomic nerve-preserving operation for rectal cancer. Dis Colon Rectum 1996;39(10):1140–1145.PubMedCrossRef
13.
go back to reference Robles Campos R, Garcia Ayllon J, Parrila Paricio P, Cifuentes Tebar J, Lujan Mompean JA, Liron Ruiz R, et al. Management of the perineal wound following abdominoperineal resection: prospective study of three methods. Br J Surg 1992;79(1):29–31.PubMedCrossRef Robles Campos R, Garcia Ayllon J, Parrila Paricio P, Cifuentes Tebar J, Lujan Mompean JA, Liron Ruiz R, et al. Management of the perineal wound following abdominoperineal resection: prospective study of three methods. Br J Surg 1992;79(1):29–31.PubMedCrossRef
14.
go back to reference Petrelli N, Rosenfield L, Herrera L, Mittelman A. The Morbidity of Perineal Wounds Following Abdominoperineal Resection for Rectal Carcinoma. J Surg Oncol 1986;32(3):138–140.PubMedCrossRef Petrelli N, Rosenfield L, Herrera L, Mittelman A. The Morbidity of Perineal Wounds Following Abdominoperineal Resection for Rectal Carcinoma. J Surg Oncol 1986;32(3):138–140.PubMedCrossRef
15.
go back to reference Khuri SF, Daley J, Henderson W, et al. The Department of Veterans Affairs' NSQIP: the first national, validated, outcome-based, risk-adjusted, and peer-controlled program for the measurement and enhancement of the quality of surgical care. National VA Surgical Quality Improvement Program. Ann Surg Oct 1998;228(4):491–507.PubMedCrossRef Khuri SF, Daley J, Henderson W, et al. The Department of Veterans Affairs' NSQIP: the first national, validated, outcome-based, risk-adjusted, and peer-controlled program for the measurement and enhancement of the quality of surgical care. National VA Surgical Quality Improvement Program. Ann Surg Oct 1998;228(4):491–507.PubMedCrossRef
16.
go back to reference Fink AS, Campbell DA, Jr., Mentzer RM, Jr., et al. The National Surgical Quality Improvement Program in non-veterans administration hospitals: initial demonstration of feasibility. Ann Surg 2002;236(3):344–353; discussion 353–344.PubMedCrossRef Fink AS, Campbell DA, Jr., Mentzer RM, Jr., et al. The National Surgical Quality Improvement Program in non-veterans administration hospitals: initial demonstration of feasibility. Ann Surg 2002;236(3):344–353; discussion 353–344.PubMedCrossRef
18.
go back to reference Dimick JB, Chen SL, Taheri PA, Henderson WG, Khuri SF, Campbell DA, Jr. Hospital costs associated with surgical complications: a report from the private-sector National Surgical Quality Improvement Program. J Am Coll Surg 2004;199(4):531–537.PubMedCrossRef Dimick JB, Chen SL, Taheri PA, Henderson WG, Khuri SF, Campbell DA, Jr. Hospital costs associated with surgical complications: a report from the private-sector National Surgical Quality Improvement Program. J Am Coll Surg 2004;199(4):531–537.PubMedCrossRef
19.
go back to reference Khuri SF, Daley J, Henderson WG. The comparative assessment and improvement of quality of surgical care in the Department of Veterans Affairs. Arch Surg 2002;137(1):20–27.PubMedCrossRef Khuri SF, Daley J, Henderson WG. The comparative assessment and improvement of quality of surgical care in the Department of Veterans Affairs. Arch Surg 2002;137(1):20–27.PubMedCrossRef
21.
go back to reference Feliciotti F, Guerrieri M, Paganini AM, De Sanctis A, et al. Long-term results of laparoscopic versus open resections for rectal cancer for 124 unselected patients. Surg Endosc 2003;17(10):1530–1535.PubMedCrossRef Feliciotti F, Guerrieri M, Paganini AM, De Sanctis A, et al. Long-term results of laparoscopic versus open resections for rectal cancer for 124 unselected patients. Surg Endosc 2003;17(10):1530–1535.PubMedCrossRef
22.
go back to reference Nandakumar G, Fleshman JW. Laparoscopy for colon and rectal cancer. Clin Colon Rectal Surg 2010;23(1):51–58.PubMedCrossRef Nandakumar G, Fleshman JW. Laparoscopy for colon and rectal cancer. Clin Colon Rectal Surg 2010;23(1):51–58.PubMedCrossRef
23.
go back to reference Dulucq JL, Wintringer P, Stabilini C, Mahajna A. Laparoscopic rectal resection with anal sphincter preservation for rectal cancer: long-term outcome. Surg Endosc 2005;19(11):1468–1474.PubMedCrossRef Dulucq JL, Wintringer P, Stabilini C, Mahajna A. Laparoscopic rectal resection with anal sphincter preservation for rectal cancer: long-term outcome. Surg Endosc 2005;19(11):1468–1474.PubMedCrossRef
24.
go back to reference Law Wl, Lee YM, Choi HK, Seto CL, Ho JW. Laparoscopic and open anterior resection for upper and mid rectal cancer: an evaluation of outcomes. Dis Colon Rectum 2006;49(8):1108–1115.PubMedCrossRef Law Wl, Lee YM, Choi HK, Seto CL, Ho JW. Laparoscopic and open anterior resection for upper and mid rectal cancer: an evaluation of outcomes. Dis Colon Rectum 2006;49(8):1108–1115.PubMedCrossRef
25.
go back to reference Delgado S, Momblan D, Salvador L, Bravo R, et al. Laparoscopic-assisted approach in rectal cancer patients: lessons learned from >200 patients. Surg Endosc 2004;18(10:1457–1462.PubMedCrossRef Delgado S, Momblan D, Salvador L, Bravo R, et al. Laparoscopic-assisted approach in rectal cancer patients: lessons learned from >200 patients. Surg Endosc 2004;18(10:1457–1462.PubMedCrossRef
Metadata
Title
Laparoscopic and Open Abdominoperineal Resection for Cancer: How Patient Selection and Complications Differ by Approach
Authors
David B. Stewart
Christopher Hollenbeak
Melissa Boltz
Publication date
01-11-2011
Publisher
Springer-Verlag
Published in
Journal of Gastrointestinal Surgery / Issue 11/2011
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-011-1663-y

Other articles of this Issue 11/2011

Journal of Gastrointestinal Surgery 11/2011 Go to the issue