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Published in: Japanese Journal of Radiology 9/2017

01-09-2017 | Original Article

The evaluation of the right inferior phrenic artery diameter in cirrhotic patients

Authors: Kaan Esen, Yuksel Balci, Sermin Tok, Enver Ucbilek, Engin Kara, Omer Kaya

Published in: Japanese Journal of Radiology | Issue 9/2017

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Abstract

Purpose

The purpose of this study is to evaluate the relationship between right inferior phrenic artery diameter and portal hypertension in cirrhotic patients.

Methods

CT examinations of 38 patients with chronic liver disease (patient group) and 40 patients without any liver disease (control group) were evaluated. The right inferior phrenic artery diameter of the patient and control group were measured. CT findings of portal hypertension, which were accepted as ascites, collaterals, splenomegaly and portal vein diameter greater than 13 mm, were determined and scored in the patient group. Patients obtained scores between one and four with respect to portal hypertension findings, and the scores were compared with phrenic artery diameters. Child-Pugh and MELD scores of the patients were also calculated.

Results

The mean diameter of the right inferior phrenic artery in the patient group was larger than that in the control group (p < 0.001). The mean phrenic artery diameter of the patients with score 1 was significantly different from those with score 2 (p = 0.028), score 3 (p = 0.001) and score 4 (p = 0.005). We found a linear and moderate relationship between phrenic artery diameter values and Child-Pugh scores (p = 0.012, r = 0.405).

Conclusion

Dilatation of the right inferior phrenic artery in cirrhotic patients may be a nonspecific sign of developing portal hypertension.
Literature
1.
go back to reference Gwon DI, Ko GY, Yoon HK, Sung KB, Lee JM, Ryu SJ, et al. Inferior phrenic artery: anatomy, variations, pathologic conditions, and interventional management. Radiographics. 2007;27:687–705.CrossRefPubMed Gwon DI, Ko GY, Yoon HK, Sung KB, Lee JM, Ryu SJ, et al. Inferior phrenic artery: anatomy, variations, pathologic conditions, and interventional management. Radiographics. 2007;27:687–705.CrossRefPubMed
2.
go back to reference Ito K, Kim MJ, Mitchell DG, Honjo K. Inferior phrenic arteries: depiction with thin-section three-dimensional contrast-enhanced dynamic MR imaging with fat suppression. J Magn Reson Imaging. 2001;13:201–6.CrossRefPubMed Ito K, Kim MJ, Mitchell DG, Honjo K. Inferior phrenic arteries: depiction with thin-section three-dimensional contrast-enhanced dynamic MR imaging with fat suppression. J Magn Reson Imaging. 2001;13:201–6.CrossRefPubMed
3.
go back to reference Gokan T, Hashimoto T, Matsui S, Kushihashi T, Nobusawa H, Munechika H. Helical CT demonstration of dilated right inferior phrenic arteries as extrahepatic collateral arteries of hepatocellular carcinomas. J Comput Assist Tomogr. 2001;25:68–73.CrossRefPubMed Gokan T, Hashimoto T, Matsui S, Kushihashi T, Nobusawa H, Munechika H. Helical CT demonstration of dilated right inferior phrenic arteries as extrahepatic collateral arteries of hepatocellular carcinomas. J Comput Assist Tomogr. 2001;25:68–73.CrossRefPubMed
4.
go back to reference Ozbülbül NI, Yurdakul M, Tola M. Does the right inferior phrenic artery have a supplying role in liver cirrhosis without hepatocellular carcinoma? A 64-slice CT study. Diagn Interv Radiol. 2011;17:239–42.PubMed Ozbülbül NI, Yurdakul M, Tola M. Does the right inferior phrenic artery have a supplying role in liver cirrhosis without hepatocellular carcinoma? A 64-slice CT study. Diagn Interv Radiol. 2011;17:239–42.PubMed
5.
go back to reference Bezerra AS, D’Ippolito G, Faintuch S, Szejnfeld J, Ahmed M. Determination of splenomegaly by CT: is there a place for a single measurement? AJR Am J Roentgenol. 2005;184:1510–3.CrossRefPubMed Bezerra AS, D’Ippolito G, Faintuch S, Szejnfeld J, Ahmed M. Determination of splenomegaly by CT: is there a place for a single measurement? AJR Am J Roentgenol. 2005;184:1510–3.CrossRefPubMed
6.
go back to reference Prassopoulos P, Daskalogiannaki M, Raissaki M, Hatjidakis A, Gourtsoyiannis N. Determination of normal splenic volume on computed tomography in relation to age, gender and body habitus. Eur Radiol. 1997;7:246–8.CrossRefPubMed Prassopoulos P, Daskalogiannaki M, Raissaki M, Hatjidakis A, Gourtsoyiannis N. Determination of normal splenic volume on computed tomography in relation to age, gender and body habitus. Eur Radiol. 1997;7:246–8.CrossRefPubMed
7.
go back to reference Kreuer S, Elgethun M, Tommack M. Imaging Findings of Cirrhosis. J Am Osteopath Coll Radiol. 2016;5:5–13. Kreuer S, Elgethun M, Tommack M. Imaging Findings of Cirrhosis. J Am Osteopath Coll Radiol. 2016;5:5–13.
8.
go back to reference Bosch J, García-Pagán JC. Complications of cirrhosis I. Portal hypertension. J Hepatol. 2000;32:141–56.CrossRefPubMed Bosch J, García-Pagán JC. Complications of cirrhosis I. Portal hypertension. J Hepatol. 2000;32:141–56.CrossRefPubMed
9.
go back to reference Wachsberg RH, Bahramipour P, Sofocleous CT, Barone A. Hepatofugal flow in the portal venous system: pathophysiology, imaging findings, and diagnostic pitfalls. RadioGraphics. 2002;22:123–40.CrossRefPubMed Wachsberg RH, Bahramipour P, Sofocleous CT, Barone A. Hepatofugal flow in the portal venous system: pathophysiology, imaging findings, and diagnostic pitfalls. RadioGraphics. 2002;22:123–40.CrossRefPubMed
10.
go back to reference Toni R, Bolondi L, Gaiani S, Re G, Calabrese L, Cavalli G, et al. Accessory ultrasonographic findings in chronic liver disease: diameter of splenic and hepatic arteries, fasting gallbladder volume, and course of left portal vein. J Clin Ultrasound. 1985;13:611–8.PubMed Toni R, Bolondi L, Gaiani S, Re G, Calabrese L, Cavalli G, et al. Accessory ultrasonographic findings in chronic liver disease: diameter of splenic and hepatic arteries, fasting gallbladder volume, and course of left portal vein. J Clin Ultrasound. 1985;13:611–8.PubMed
13.
go back to reference Koh C, Heller T. Approach to the diagnosis of portal hypertension. Clin Liver Dis. 2012;1:133–5.CrossRef Koh C, Heller T. Approach to the diagnosis of portal hypertension. Clin Liver Dis. 2012;1:133–5.CrossRef
14.
go back to reference Takeuchi Y, Arai Y, Inaba Y, Ohno K, Maeda T, Itai Y. Extrahepatic arterial supply to the liver: observation with a unified CT and angiography system during temporary balloon occlusion of the proper hepatic artery. Radiology. 1998;209:121–8.CrossRefPubMed Takeuchi Y, Arai Y, Inaba Y, Ohno K, Maeda T, Itai Y. Extrahepatic arterial supply to the liver: observation with a unified CT and angiography system during temporary balloon occlusion of the proper hepatic artery. Radiology. 1998;209:121–8.CrossRefPubMed
15.
go back to reference La Mura V, Nicolini A, Tosetti G, Primignani M. Cirrhosis and portal hypertension: the importance of risk stratification, the role of hepatic venous pressure gradient measurement. World J Hepatol. 2015;7:688–95.CrossRefPubMedPubMedCentral La Mura V, Nicolini A, Tosetti G, Primignani M. Cirrhosis and portal hypertension: the importance of risk stratification, the role of hepatic venous pressure gradient measurement. World J Hepatol. 2015;7:688–95.CrossRefPubMedPubMedCentral
16.
go back to reference Garcia-Tsao G, Friedman S, Iredale J, Pinzani M. Now there are many (stages) where before there was one: in search of a pathophysiological classification of cirrhosis. Hepatology. 2010;51:1445–9.CrossRefPubMedPubMedCentral Garcia-Tsao G, Friedman S, Iredale J, Pinzani M. Now there are many (stages) where before there was one: in search of a pathophysiological classification of cirrhosis. Hepatology. 2010;51:1445–9.CrossRefPubMedPubMedCentral
17.
19.
go back to reference D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol. 2006;44:217–31.CrossRefPubMed D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol. 2006;44:217–31.CrossRefPubMed
20.
go back to reference Ripoll C, Groszmann R, Garcia-Tsao G, Grace N, Burroughs A, Planas R, et al. Portal Hypertension Collaborative Group. Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis. Gastroenterology. 2007;133:481–8.CrossRefPubMed Ripoll C, Groszmann R, Garcia-Tsao G, Grace N, Burroughs A, Planas R, et al. Portal Hypertension Collaborative Group. Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis. Gastroenterology. 2007;133:481–8.CrossRefPubMed
21.
go back to reference Mehta G, Gustot T, Mookerjee RP, Garcia-Pagan JC, Fallon MB, Shah VH, et al. Inflammation and portal hypertension—the undiscovered country. J Hepatol. 2014;61:155–63.CrossRefPubMed Mehta G, Gustot T, Mookerjee RP, Garcia-Pagan JC, Fallon MB, Shah VH, et al. Inflammation and portal hypertension—the undiscovered country. J Hepatol. 2014;61:155–63.CrossRefPubMed
22.
go back to reference Albilllos A, Garcia-Tsao G. Classification of cirrhosis: the clinical use of HVPG measurements. Dis Mark. 2011;31:121–8.CrossRef Albilllos A, Garcia-Tsao G. Classification of cirrhosis: the clinical use of HVPG measurements. Dis Mark. 2011;31:121–8.CrossRef
23.
go back to reference de Franchis R, Primignani M. Natural history of portal hypertension in patients with cirrhosis. Clin Liver Dis. 2001;5:645–63.CrossRefPubMed de Franchis R, Primignani M. Natural history of portal hypertension in patients with cirrhosis. Clin Liver Dis. 2001;5:645–63.CrossRefPubMed
24.
go back to reference Kuo CH, Changchien CS, Tai DI, Chen JJ. Portal vein velocity by duplex Doppler ultrasound as an indication of the clinical severity of portal hypertension. Changgeng Yi Xue Za Zhi. 1995;18:217–23.PubMed Kuo CH, Changchien CS, Tai DI, Chen JJ. Portal vein velocity by duplex Doppler ultrasound as an indication of the clinical severity of portal hypertension. Changgeng Yi Xue Za Zhi. 1995;18:217–23.PubMed
25.
go back to reference Mittal P, Gupta R, Mittal G, Kalia V. Association between portal vein color Doppler findings and the severity of disease in cirrhotic patients with portal hypertension. Iran J Radiol. 2011;8:211–7.CrossRefPubMedPubMedCentral Mittal P, Gupta R, Mittal G, Kalia V. Association between portal vein color Doppler findings and the severity of disease in cirrhotic patients with portal hypertension. Iran J Radiol. 2011;8:211–7.CrossRefPubMedPubMedCentral
26.
go back to reference Amitrano L, Guardascione MA, Ames PR. Coagulation abnormalities in cirrhotic patients with portal vein thrombosis. Clin Lab. 2007;53:583–9.PubMed Amitrano L, Guardascione MA, Ames PR. Coagulation abnormalities in cirrhotic patients with portal vein thrombosis. Clin Lab. 2007;53:583–9.PubMed
Metadata
Title
The evaluation of the right inferior phrenic artery diameter in cirrhotic patients
Authors
Kaan Esen
Yuksel Balci
Sermin Tok
Enver Ucbilek
Engin Kara
Omer Kaya
Publication date
01-09-2017
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 9/2017
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-017-0662-7

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