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Japanese Journal of Radiology
Published in: Japanese Journal of Radiology 6/2017

01-06-2017 | Original Article

Diffuse-type gastric cancer: specific enhancement pattern on multiphasic contrast-enhanced computed tomography

Authors: Daisuke Tsurumaru, Mitsutoshi Miyasaka, Toshio Muraki, Yoshiki Asayama, Akihiro Nishie, Eiji Oki, Minako Hirahashi, Tomoyuki Hida, Hiroshi Honda

Published in: Japanese Journal of Radiology | Issue 6/2017

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Abstract

Purpose

To evaluate the enhancement pattern of diffuse-type gastric cancers (DGCs) on multiphasic contrast-enhanced computed tomography gastrography (CECTG).

Methods and materials

We studied 21 consecutive clinically diagnosed DGC patients who underwent CECTG. Gastric distension was obtained using effervescent granules. CT images were obtained 40 s (arterial phase) and 240 s (delayed phase) after injection of a nonionic contrast material. Two radiologists reviewed the CT images and analyzed layers and enhancement patterns. The readers evaluated the enhancement degree (mild, moderate, or marked) and calculated CT attenuation values by placing circular regions of interest (ROIs) within each layer of the lesion. The CT findings of 11 operated cases were correlated with pathological results.

Results

Most lesions were double-layered in the arterial phase, with a moderately enhanced inner layer and a mildly enhanced outer layer, and single-layered in the delayed phase. The mean attenuation value of the inner layer (146 ± 32.8 HU) was significantly higher than that of the outer layer (80.4 ± 15.5 HU) in the arterial phase (p = 0.0001). In the pathological analysis, wall stratification was preserved in nine cases and not preserved in two cases.

Conclusion

Most DGCs showed a double-layered pattern in the arterial phase and a single-layered pattern with moderate enhancement in the delayed phase.
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Metadata
Title
Diffuse-type gastric cancer: specific enhancement pattern on multiphasic contrast-enhanced computed tomography
Authors
Daisuke Tsurumaru
Mitsutoshi Miyasaka
Toshio Muraki
Yoshiki Asayama
Akihiro Nishie
Eiji Oki
Minako Hirahashi
Tomoyuki Hida
Hiroshi Honda
Publication date
01-06-2017
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 6/2017
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-017-0631-1

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