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Japanese Journal of Radiology
Published in: Japanese Journal of Radiology 3/2017

01-03-2017 | Original Article

T1 mapping using saturation recovery single-shot acquisition at 3-tesla magnetic resonance imaging in hypertrophic cardiomyopathy: comparison to late gadolinium enhancement

Authors: Ryo Ogawa, Tomoyuki Kido, Masashi Nakamura, Teruhito Kido, Akira Kurata, Teruyoshi Uetani, Akiyoshi Ogimoto, Masao Miyagawa, Teruhito Mochizuki

Published in: Japanese Journal of Radiology | Issue 3/2017

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Abstract

Purpose

We evaluated the T1 values of segments and slices and the reproducibility in healthy controls, using saturation recovery single-shot acquisition (SASHA) at 3T magnetic resonance imaging. Moreover, we examined the difference in T1 values between hypertrophic cardiomyopathy (HCM) and healthy controls, and compared those with late gadolinium enhancement (LGE).

Materials and methods

Twenty-one HCM patients and 10 healthy controls underwent T1 mapping before and after contrast administration. T1 values were measured in 12 segments.

Results

Native T1 values were significantly longer in HCM than in healthy controls [1373 ms (1312–1452 ms) vs. 1279 ms (1229–1326 ms); p < 0.0001]. Even in HCM segments without LGE, native T1 values were significantly longer than in healthy control segments [1366 ms (1300–1439 ms) vs. 1279 ms (1229–1326 ms); p < 0.0001]. Using a cutoff value of 1327 ms for septal native T1 values, we differentiated between HCM and healthy controls with 95% sensitivity, 90% specificity, 94% accuracy, and an area under the curve of 0.95.

Conclusions

Native T1 values using a SASHA at 3T could differentiate HCM from healthy controls. Moreover, native T1 values have the potential to detect abnormal myocardium that cannot be identified adequately by LGE in HCM.
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Metadata
Title
T1 mapping using saturation recovery single-shot acquisition at 3-tesla magnetic resonance imaging in hypertrophic cardiomyopathy: comparison to late gadolinium enhancement
Authors
Ryo Ogawa
Tomoyuki Kido
Masashi Nakamura
Teruhito Kido
Akira Kurata
Teruyoshi Uetani
Akiyoshi Ogimoto
Masao Miyagawa
Teruhito Mochizuki
Publication date
01-03-2017
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 3/2017
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-017-0611-5

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