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01-07-2015 | Case Report

Mediastinal paraganglioma

Authors: Yoko Takashima, Takeshi Kamitani, Satoshi Kawanami, Michinobu Nagao, Masato Yonezawa, Yuzo Yamasaki, Shingo Baba, Hidetake Yabuuchi, Tomoyuki Hida, Kenichi Kohashi, Katsuya Nakamura, Hiromichi Sonoda, Yoshinao Oda, Hiroshi Honda

Published in: Japanese Journal of Radiology | Issue 7/2015

Abstract

We present a case of mediastinal paraganglioma with radiologic–pathologic correlation. A 48-year-old woman was found incidentally to have a middle mediastinal mass on CT. The mass showed iso-signal intensity compared to that of muscle on T1-weighted images and high signal intensity on T2-weighted images. The lesion showed intermediate intensity on diffusion-weighted imaging, and its apparent diffusion coefficient was 1.72 × 10⁻³ mm²/s. A contrast-enhanced dynamic study revealed a rapid peak and washout enhancement pattern. ¹⁸F-FDG-PET revealed abnormal uptake in the mediastinal tumor with a maximal standardized uptake value of 7.88. ¹²³I-meta-iodobenzylguanidine scintigraphy also showed abnormal uptake in the tumor. These findings corresponded to the hypervascularity, rich stroma, low nuclear/cytoplasmic ratio, and nest-forming proliferation of tumor cells with positive neuroendocrine markers.

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Title: Mediastinal paraganglioma
Authors: Yoko Takashima
Takeshi Kamitani
Satoshi Kawanami
Michinobu Nagao
Masato Yonezawa
Yuzo Yamasaki
Shingo Baba
Hidetake Yabuuchi
Tomoyuki Hida
Kenichi Kohashi
Katsuya Nakamura
Hiromichi Sonoda
Yoshinao Oda
Hiroshi Honda
Publication date: 01-07-2015
Publisher: Springer Japan
Published in: Japanese Journal of Radiology / Issue 7/2015
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-015-0436-z

At a glance: The STEP trials

Springer Medicine

Mediastinal paraganglioma

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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