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Japanese Journal of Radiology

Published in:

01-01-2014 | Original Article

Hemorrhage in cerebral fat embolisms in a cat model using triolein dependent on the physical properties of triolein

Authors: Yong-Woo Kim, Hak J. Kim, Seon H. Choi, Byungmann Cho, Lee Hwangbo, Dong C. Kim

Published in: Japanese Journal of Radiology | Issue 1/2014

Abstract

Purpose

Hemorrhage is a finding of clinical fat embolism syndrome. The purpose of the present study was to evaluate the occurrence of hemorrhage in the cat brain by SW MR imaging after infusion of triolein as a bolus or as an emulsion into the carotid artery.

Materials and methods

Twenty-two cats were divided into two groups according to the type of triolein infused: group 1 (n = 11) was infused with a 0.1 ml triolein bolus, group 2 (n = 11) with triolein emulsion containing 0.1 ml triolein in 20 ml saline. SW imaging was performed before and after triolein infusion (at 2 h, 1 and 4 days). After MR imaging on day 4, cats were sacrificed and brains were immediately excised. Hemorrhage was evaluated using H&E staining.

Results

Hemorrhage was observed in eight cats in group 1, in no cats in group 2. Hemorrhage on SW images was found to correspond with light microscopy.

Conclusions

SW images revealed hemorrhage in lesion hemispheres infused with triolein bolus. However, there was no evidence of hemorrhage infused with emulsified triolein. Thus, the occurrence of hemorrhage in cerebral fat embolism may depend on fat status.

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Title: Hemorrhage in cerebral fat embolisms in a cat model using triolein dependent on the physical properties of triolein
Authors: Yong-Woo Kim
Hak J. Kim
Seon H. Choi
Byungmann Cho
Lee Hwangbo
Dong C. Kim
Publication date: 01-01-2014
Publisher: Springer Japan
Published in: Japanese Journal of Radiology / Issue 1/2014
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-013-0265-x

At a glance: The STEP trials

Springer Medicine

Hemorrhage in cerebral fat embolisms in a cat model using triolein dependent on the physical properties of triolein

Abstract

Purpose

Materials and methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusions

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