Skip to main content
Top
Published in: Japanese Journal of Radiology 1/2014

01-01-2014 | Original Article

Peribronchovascular haze: a frequently observed finding on chest X-rays in the acute phase of Kawasaki disease

Authors: Shingo Moriya, Jun Aoki, Masahiko Tashiro, Ayako Taketomi-Takahashi, Yoshito Tsushima

Published in: Japanese Journal of Radiology | Issue 1/2014

Login to get access

Abstract

Purpose

To evaluate the frequency of peribronchovascular haze on chest X-rays (CXR) in patients with Kawasaki disease (KD), a finding not previously emphasized, and to contrast this finding with clinical, laboratory and echocardiographic findings.

Methods

Sixty-nine patients diagnosed as KD from January 2010 to December 2011 were eligible for this study. The initial CXRs were retrospectively reviewed by two radiologists for the presence of peribronchovascular haze and related findings. Echocardiography was reviewed by one pediatrician for the presence of coronary artery abnormalities. The follow up CXRs and post-remission echocardiograms were also reviewed. Patients’ medical records were reviewed for clinical findings. Correlation between CXR findings and clinical findings were assessed.

Results

On the initial CXR, peribronchovascular haze was observed in 57/69 patients (82.6 %). Twenty-nine out of 69 patients showed abnormalities on echocardiogram (42.0 %). In the follow-up studies, CXR findings were improved in 25/29 patients (86.2 %). The frequencies of five principal clinical features of KD were from 55.1 to 88.4 %. There was no statistically significant correlation between the CXR finding and clinical findings.

Conclusion

Peribronchovascular haze on CXR was observed in the acute phase of KD as frequently as the principal clinical features of KD, and more frequently than echocardiographic abnormalities.
Literature
1.
go back to reference Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi. 1967;16:178–222 in Japanese.PubMed Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi. 1967;16:178–222 in Japanese.PubMed
2.
go back to reference Jane WN, Takahashi M, Michael AG, et al. Diagnosis, treatment, and long-term management of Kawasaki disease. Circulation. 2004;110:2747–71.CrossRef Jane WN, Takahashi M, Michael AG, et al. Diagnosis, treatment, and long-term management of Kawasaki disease. Circulation. 2004;110:2747–71.CrossRef
3.
go back to reference Crystal MA, Syan SK, Yeung RSM, Dipchand AI, McCrindle BW. Echocardiographic and electrocardiographic trends in children with acute Kawasaki disease. Can J Cardiol. 2008;24(10):776–80.PubMedCrossRef Crystal MA, Syan SK, Yeung RSM, Dipchand AI, McCrindle BW. Echocardiographic and electrocardiographic trends in children with acute Kawasaki disease. Can J Cardiol. 2008;24(10):776–80.PubMedCrossRef
4.
go back to reference Kiguchi H, Kimura H, Kosaka M, Ikawa A. Coronary artery change in Kawasaki disease—detection and follow up of the coronary aneurysm by two-dimensional echocardiography. Joshiidaisi. 1987;57(10):1211–7 (in Japanese). Kiguchi H, Kimura H, Kosaka M, Ikawa A. Coronary artery change in Kawasaki disease—detection and follow up of the coronary aneurysm by two-dimensional echocardiography. Joshiidaisi. 1987;57(10):1211–7 (in Japanese).
5.
go back to reference Tsai CH, Lee JK, Kao CH, Chang JS, Shih WJ. Kawasaki disease evaluated by two-dimensional echocardiogram and dipyridamole 201Tl-chloride myocardial SPET. Nucl Med Commun. 1997;18(5):412–8.PubMedCrossRef Tsai CH, Lee JK, Kao CH, Chang JS, Shih WJ. Kawasaki disease evaluated by two-dimensional echocardiogram and dipyridamole 201Tl-chloride myocardial SPET. Nucl Med Commun. 1997;18(5):412–8.PubMedCrossRef
6.
go back to reference Baer AZ, Rubin LG, Shapiro CA, et al. Prevalence of coronary artery lesions on the initial echocardiogram in Kawasaki syndrome. Arch Pediatr Adolesc Med. 2006;160(7):686–90.PubMedCrossRef Baer AZ, Rubin LG, Shapiro CA, et al. Prevalence of coronary artery lesions on the initial echocardiogram in Kawasaki syndrome. Arch Pediatr Adolesc Med. 2006;160(7):686–90.PubMedCrossRef
7.
go back to reference Heuclin T, Dubos F, Hue V, et al. Increased detection rate of Kawasaki disease using new diagnostic algorithm, including early use of echocardiography. J Pediatr. 2009;155(5):695–9.PubMedCrossRef Heuclin T, Dubos F, Hue V, et al. Increased detection rate of Kawasaki disease using new diagnostic algorithm, including early use of echocardiography. J Pediatr. 2009;155(5):695–9.PubMedCrossRef
8.
go back to reference Yu JJ, Jang WS, Ko HK, et al. Perivascular brightness of coronary arteries in Kawasaki disease. J Pediatr. 2011;159(3):454–7.PubMedCrossRef Yu JJ, Jang WS, Ko HK, et al. Perivascular brightness of coronary arteries in Kawasaki disease. J Pediatr. 2011;159(3):454–7.PubMedCrossRef
9.
go back to reference Anderson MS, Todd JK, Glode MP. Delayed diagnosis of Kawasaki syndrome: an analysis of the problem. Pediatrics. 2005;115:e428–33.PubMedCrossRef Anderson MS, Todd JK, Glode MP. Delayed diagnosis of Kawasaki syndrome: an analysis of the problem. Pediatrics. 2005;115:e428–33.PubMedCrossRef
10.
go back to reference Rowley AH, Gonzalez-Crussi F, Gidding SS, et al. Incomplete Kawasaki disease with coronary artery involvement. J Pediatr. 1987;110:409–13.PubMedCrossRef Rowley AH, Gonzalez-Crussi F, Gidding SS, et al. Incomplete Kawasaki disease with coronary artery involvement. J Pediatr. 1987;110:409–13.PubMedCrossRef
11.
go back to reference Council on Cardiovascular Disease in the Young; Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease; American Heart Association (2001) Diagnostic guidelines for Kawasaki disease. Circulation 103:335–36. Council on Cardiovascular Disease in the Young; Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease; American Heart Association (2001) Diagnostic guidelines for Kawasaki disease. Circulation 103:335–36.
12.
go back to reference Uramoto K, Ikawa A, Watanabe C, et al. Study of chest X-ray findings in Kawasaki disease. Shoni Naika. 1978;10:320 in Japanese. Uramoto K, Ikawa A, Watanabe C, et al. Study of chest X-ray findings in Kawasaki disease. Shoni Naika. 1978;10:320 in Japanese.
13.
go back to reference Umezawa T, Saji T, Matsuo N, Odagiri K. Chest X-ray findings in the acute phase of Kawasaki disease. Pediatr Radiol. 1989;20:48–51.PubMedCrossRef Umezawa T, Saji T, Matsuo N, Odagiri K. Chest X-ray findings in the acute phase of Kawasaki disease. Pediatr Radiol. 1989;20:48–51.PubMedCrossRef
14.
go back to reference Shibuya K, Atobe T, Naoe S, Masuda H, Tanaka N, Kusakawa S. Histological study of pulmonary lesions in autopsy cases with Kawasaki disease. Prog Med. 1986;6:35–42 (in Japanese). Shibuya K, Atobe T, Naoe S, Masuda H, Tanaka N, Kusakawa S. Histological study of pulmonary lesions in autopsy cases with Kawasaki disease. Prog Med. 1986;6:35–42 (in Japanese).
15.
go back to reference Amano S, Hazama F, Kubagawa H, Tasaka K, Haebara H, Hamashima Y. General pathology of Kawasaki disease. Acta Pathol Jpn. 1980;30(5):681–94.PubMed Amano S, Hazama F, Kubagawa H, Tasaka K, Haebara H, Hamashima Y. General pathology of Kawasaki disease. Acta Pathol Jpn. 1980;30(5):681–94.PubMed
Metadata
Title
Peribronchovascular haze: a frequently observed finding on chest X-rays in the acute phase of Kawasaki disease
Authors
Shingo Moriya
Jun Aoki
Masahiko Tashiro
Ayako Taketomi-Takahashi
Yoshito Tsushima
Publication date
01-01-2014
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 1/2014
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-013-0267-8

Other articles of this Issue 1/2014

Japanese Journal of Radiology 1/2014 Go to the issue