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Published in: International Journal of Computer Assisted Radiology and Surgery 1/2019

01-01-2019 | Original Article

MR-conditional steerable needle robot for intracerebral hemorrhage removal

Authors: Yue Chen, Isuru S. Godage, Saikat Sengupta, Cindy Lin Liu, Kyle D. Weaver, Eric J. Barth

Published in: International Journal of Computer Assisted Radiology and Surgery | Issue 1/2019

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Abstract

Background

Intracerebral hemorrhage (ICH) is one of the deadliest forms of stroke in the USA. Conventional surgical techniques such as craniotomy or stereotactic aspiration disrupt a large volume of healthy brain tissue in their attempts to reach the surgical site. Consequently, the surviving patients suffer from debilitating complications.

Methods

We fabricated a novel MR-conditional steerable needle robot for ICH treatment. The robot system is powered by a custom-designed high power and low-cost pneumatic motor. We tested the robot’s targeting accuracy and MR-conditionality performance, and performed phantom evacuation experiment under MR image guidance.

Results

Experiments demonstrate that the robotic hardware is MR-conditional; the robot has the targeting accuracy of 1.26 ± 1.22 mm in bench-top tests. With real-time MRI guidance, the robot successfully reached the desired target and evacuated an 11.3 ml phantom hematoma in 9 min.

Conclusion

MRI-guided steerable needle robotic system is a potentially feasible approach for ICH treatment by providing accurate needle guidance and intraoperative surgical outcome evaluation.
Literature
1.
go back to reference Tapia-Perez JH, Zilke R, Schneider T (2016) Match-study of statin therapy in spontaneous intracerebral hemorrhage: is the discontinuation reasonable? J Neurosurg Sci 60:301–312PubMed Tapia-Perez JH, Zilke R, Schneider T (2016) Match-study of statin therapy in spontaneous intracerebral hemorrhage: is the discontinuation reasonable? J Neurosurg Sci 60:301–312PubMed
2.
go back to reference Etminan N, Beseoglu K, Turowski B, Steiger H-J, Hänggi D (2012) Perfusion CT in patients with spontaneous lobar intracerebral hemorrhage: effect of surgery on perihemorrhagic perfusion. Stroke 43:759–763CrossRefPubMed Etminan N, Beseoglu K, Turowski B, Steiger H-J, Hänggi D (2012) Perfusion CT in patients with spontaneous lobar intracerebral hemorrhage: effect of surgery on perihemorrhagic perfusion. Stroke 43:759–763CrossRefPubMed
3.
4.
go back to reference Maira G, Anile C, Colosimo C, Rossi GF (2002) Surgical treatment of primary supratentorial intracerebral hemorrhage in stuporous and comatose patients. Neurol Res 24:54–60CrossRefPubMed Maira G, Anile C, Colosimo C, Rossi GF (2002) Surgical treatment of primary supratentorial intracerebral hemorrhage in stuporous and comatose patients. Neurol Res 24:54–60CrossRefPubMed
5.
go back to reference Burgner J, Swaney PJ, Lathrop RA, Weaver KD, Webster RJ (2013) Debulking from within: a robotic steerable cannula for intracerebral hemorrhage evacuation. IEEE Trans Biomed Eng 60:2567–2575CrossRefPubMed Burgner J, Swaney PJ, Lathrop RA, Weaver KD, Webster RJ (2013) Debulking from within: a robotic steerable cannula for intracerebral hemorrhage evacuation. IEEE Trans Biomed Eng 60:2567–2575CrossRefPubMed
6.
go back to reference Granna J, Godage IS, Wirz R, Weaver KD, Webster RJ, Burgner-Kahrs J (2016) A 3-D volume coverage path planning algorithm with application to intracerebral hemorrhage evacuation. IEEE Robot Autom Lett 1:876–883CrossRef Granna J, Godage IS, Wirz R, Weaver KD, Webster RJ, Burgner-Kahrs J (2016) A 3-D volume coverage path planning algorithm with application to intracerebral hemorrhage evacuation. IEEE Robot Autom Lett 1:876–883CrossRef
7.
go back to reference Godage IS, Remirez AA, Wirz R, Weaver KD, Burgner-Kahrs J, Webster RJ (2015) Robotic intracerebral hemorrhage evacuation: an in-scanner approach with concentric tube robots. In: 2015 IEEE/RSJ international conference on intelligent robots and systems (IROS), 2015, pp 1447–1452 Godage IS, Remirez AA, Wirz R, Weaver KD, Burgner-Kahrs J, Webster RJ (2015) Robotic intracerebral hemorrhage evacuation: an in-scanner approach with concentric tube robots. In: 2015 IEEE/RSJ international conference on intelligent robots and systems (IROS), 2015, pp 1447–1452
8.
go back to reference Miga MI, Paulsen KD, Hoopes PJ, Kennedy FE, Hartov A, Roberts DW (2000) In vivo quantification of a homogeneous brain deformation model for updating preoperative images during surgery. IEEE Trans Biomed Eng 47:266–273CrossRefPubMed Miga MI, Paulsen KD, Hoopes PJ, Kennedy FE, Hartov A, Roberts DW (2000) In vivo quantification of a homogeneous brain deformation model for updating preoperative images during surgery. IEEE Trans Biomed Eng 47:266–273CrossRefPubMed
9.
go back to reference Fiebach JB, Schellinger PD, Gass A, Kucinski T, Siebler M, Villringer A, Ölkers P, Hirsch JG, Heiland S, Wilde P (2004) Stroke magnetic resonance imaging is accurate in hyperacute intracerebral hemorrhage: a multicenter study on the validity of stroke imaging. Stroke 35:502–506CrossRefPubMed Fiebach JB, Schellinger PD, Gass A, Kucinski T, Siebler M, Villringer A, Ölkers P, Hirsch JG, Heiland S, Wilde P (2004) Stroke magnetic resonance imaging is accurate in hyperacute intracerebral hemorrhage: a multicenter study on the validity of stroke imaging. Stroke 35:502–506CrossRefPubMed
10.
go back to reference Jolesz FA (2003) Future perspectives in intraoperative imaging. In: Bernays RL, Imhof HG, Yonekawa Y (eds) Intraoperative Imaging in Neurosurgery, vol 85. Springer, Vienna, pp 7–13CrossRef Jolesz FA (2003) Future perspectives in intraoperative imaging. In: Bernays RL, Imhof HG, Yonekawa Y (eds) Intraoperative Imaging in Neurosurgery, vol 85. Springer, Vienna, pp 7–13CrossRef
11.
go back to reference Sengupta S, Tadanki S, Gore JC, Welch EB (2014) Prospective real-time head motion correction using inductively coupled wireless NMR probes. Magn Reson Med 72:971–985CrossRefPubMed Sengupta S, Tadanki S, Gore JC, Welch EB (2014) Prospective real-time head motion correction using inductively coupled wireless NMR probes. Magn Reson Med 72:971–985CrossRefPubMed
12.
go back to reference Wang W, Viswanathan AN, Damato AL, Chen Y, Tse Z, Pan L, Tokuda J, Seethamraju RT, Dumoulin CL, Schmidt EJ (2015) Evaluation of an active magnetic resonance tracking system for interstitial brachytherapy. Med Phys 42:7114–7121CrossRefPubMedPubMedCentral Wang W, Viswanathan AN, Damato AL, Chen Y, Tse Z, Pan L, Tokuda J, Seethamraju RT, Dumoulin CL, Schmidt EJ (2015) Evaluation of an active magnetic resonance tracking system for interstitial brachytherapy. Med Phys 42:7114–7121CrossRefPubMedPubMedCentral
13.
go back to reference Chen Y, Wang W, Schmidt EJ, Kwok K-W, Viswanathan AN, Cormack R, Tse ZTH (2016) Design and fabrication of MR-tracked metallic stylet for gynecologic brachytherapy. IEEE/ASME Trans Mechatron 21:956–962CrossRef Chen Y, Wang W, Schmidt EJ, Kwok K-W, Viswanathan AN, Cormack R, Tse ZTH (2016) Design and fabrication of MR-tracked metallic stylet for gynecologic brachytherapy. IEEE/ASME Trans Mechatron 21:956–962CrossRef
14.
go back to reference Kwok K-W, Lee K-H, Chen Y, Wang W, Hu Y, Chow GC, Zhang HS, Stevenson WG, Kwong RY, Luk W (2014) Interfacing fast multi-phase cardiac image registration with MRI-based catheter tracking for MRI-guided electrophysiological ablative procedures. Am Heart Assoc, Dallas Kwok K-W, Lee K-H, Chen Y, Wang W, Hu Y, Chow GC, Zhang HS, Stevenson WG, Kwong RY, Luk W (2014) Interfacing fast multi-phase cardiac image registration with MRI-based catheter tracking for MRI-guided electrophysiological ablative procedures. Am Heart Assoc, Dallas
15.
go back to reference Kwok K-W, Chen Y, Chau TC, Luk W, Nilsson KR, Schmidt EJ, Zion TT (2014) MRI-based visual and haptic catheter feedback: simulating a novel system’s contribution to efficient and safe MRI-guided cardiac electrophysiology procedures. J Cardiovasc Magn Reson 16:O50CrossRefPubMedCentral Kwok K-W, Chen Y, Chau TC, Luk W, Nilsson KR, Schmidt EJ, Zion TT (2014) MRI-based visual and haptic catheter feedback: simulating a novel system’s contribution to efficient and safe MRI-guided cardiac electrophysiology procedures. J Cardiovasc Magn Reson 16:O50CrossRefPubMedCentral
16.
go back to reference Chen Y, Zion TT, Wang W, Kwong RY, Stevenson WG, Schmidt EJ (2015) Intra-cardiac MR imaging and MR-tracking catheter for improved MR-guided EP. J Cardiovasc Magn Reson 17:P237CrossRefPubMedCentral Chen Y, Zion TT, Wang W, Kwong RY, Stevenson WG, Schmidt EJ (2015) Intra-cardiac MR imaging and MR-tracking catheter for improved MR-guided EP. J Cardiovasc Magn Reson 17:P237CrossRefPubMedCentral
17.
go back to reference Masamune K, Kobayashi E, Masutani Y, Suzuki M, Dohi T, Iseki H, Takakura K (1995) Development of an MRI-compatible needle insertion manipulator for stereotactic neurosurgery. J Image Guided Surg 1:242–248CrossRef Masamune K, Kobayashi E, Masutani Y, Suzuki M, Dohi T, Iseki H, Takakura K (1995) Development of an MRI-compatible needle insertion manipulator for stereotactic neurosurgery. J Image Guided Surg 1:242–248CrossRef
18.
go back to reference Pandya S, Motkoski JW, Serrano-Almeida C, Greer AD, Latour I, Sutherland GR (2009) Advancing neurosurgery with image-guided robotics. J Neurosurg 111:1141–1149CrossRefPubMed Pandya S, Motkoski JW, Serrano-Almeida C, Greer AD, Latour I, Sutherland GR (2009) Advancing neurosurgery with image-guided robotics. J Neurosurg 111:1141–1149CrossRefPubMed
19.
go back to reference Sheng J, Desai JP (2015) Towards a SMA-actuated neurosurgical intracerebral hemorrhage evacuation (NICHE) robot. In: 2015 IEEE/RSJ international conference on intelligent robots and systems (IROS), pp 3805–3810 Sheng J, Desai JP (2015) Towards a SMA-actuated neurosurgical intracerebral hemorrhage evacuation (NICHE) robot. In: 2015 IEEE/RSJ international conference on intelligent robots and systems (IROS), pp 3805–3810
20.
go back to reference Su H, Li G, Rucker DC, Webster RJ III, Fischer GS (2016) A concentric tube continuum robot with piezoelectric actuation for MRI-guided closed-loop targeting. Ann Biomed Eng 44:2863–2873CrossRefPubMedPubMedCentral Su H, Li G, Rucker DC, Webster RJ III, Fischer GS (2016) A concentric tube continuum robot with piezoelectric actuation for MRI-guided closed-loop targeting. Ann Biomed Eng 44:2863–2873CrossRefPubMedPubMedCentral
21.
go back to reference Chen Y, Godage IS, Sengupta S, Liu CL, Weaver KD, Barth EJ, Webster RJ (2017) An MRI-compatible robot for intracerebral hemorrhage removal. In: 2017 design of medical devices conference, pp V001T08A019–V001T08A019 Chen Y, Godage IS, Sengupta S, Liu CL, Weaver KD, Barth EJ, Webster RJ (2017) An MRI-compatible robot for intracerebral hemorrhage removal. In: 2017 design of medical devices conference, pp V001T08A019–V001T08A019
22.
go back to reference ASTM. F2503 (2005) Standard practice for marking medical devices and other items for safety in the magnetic resonance environment. http://www.astm.org/. Accessed 21 Jan 2018 ASTM. F2503 (2005) Standard practice for marking medical devices and other items for safety in the magnetic resonance environment. http://​www.​astm.​org/​. Accessed 21 Jan 2018
24.
go back to reference Chen Y, Godage IS, Tse ZTH, Webster RJ, Barth EJ (2017) Characterization and control of a pneumatic motor for MR-conditional robotic applications. IEEE/ASME Trans Mechatron 22:2780–2789CrossRef Chen Y, Godage IS, Tse ZTH, Webster RJ, Barth EJ (2017) Characterization and control of a pneumatic motor for MR-conditional robotic applications. IEEE/ASME Trans Mechatron 22:2780–2789CrossRef
25.
go back to reference Whitney DE (1969) Resolved motion rate control of manipulators and human prostheses. IEEE Trans Man Mach Syst 10:47–53CrossRef Whitney DE (1969) Resolved motion rate control of manipulators and human prostheses. IEEE Trans Man Mach Syst 10:47–53CrossRef
26.
go back to reference Chan AY, Tran DKT, Gill AS, Hsu FP, Vadera S (2016) Stereotactic robot-assisted MRI-guided laser thermal ablation of radiation necrosis in the posterior cranial fossa. Neurosurg Focus 41:E5CrossRefPubMed Chan AY, Tran DKT, Gill AS, Hsu FP, Vadera S (2016) Stereotactic robot-assisted MRI-guided laser thermal ablation of radiation necrosis in the posterior cranial fossa. Neurosurg Focus 41:E5CrossRefPubMed
27.
go back to reference Fitzpatrick JM, West JB, Maurer CR Jr (1998) Predicting error in rigid-body point-based registration. IEEE Trans Med Imaging 17:694–702CrossRefPubMed Fitzpatrick JM, West JB, Maurer CR Jr (1998) Predicting error in rigid-body point-based registration. IEEE Trans Med Imaging 17:694–702CrossRefPubMed
28.
go back to reference Sinclair T, Mougenot C, Kivinen J (2012) MatMRI and MatHIFU: Matlab toolboxes for real-time monitoring and control of MR-HIFU. In: 12th international society for therapeutic ultrasound symposium, Heidelberg, Germany, pp 156–161 Sinclair T, Mougenot C, Kivinen J (2012) MatMRI and MatHIFU: Matlab toolboxes for real-time monitoring and control of MR-HIFU. In: 12th international society for therapeutic ultrasound symposium, Heidelberg, Germany, pp 156–161
29.
go back to reference Chen Y, Kwok K-W, Tse ZTH (2014) An MR-conditional high-torque pneumatic stepper motor for MRI-guided and robot-assisted intervention. Ann Biomed Eng 42:1823–1833CrossRefPubMedPubMedCentral Chen Y, Kwok K-W, Tse ZTH (2014) An MR-conditional high-torque pneumatic stepper motor for MRI-guided and robot-assisted intervention. Ann Biomed Eng 42:1823–1833CrossRefPubMedPubMedCentral
30.
go back to reference Chen Y, Mershon CD, Tse ZTH (2015) A 10-mm MR-conditional unidirectional pneumatic stepper motor. IEEE/ASME Trans Mechatron 20:782–788CrossRef Chen Y, Mershon CD, Tse ZTH (2015) A 10-mm MR-conditional unidirectional pneumatic stepper motor. IEEE/ASME Trans Mechatron 20:782–788CrossRef
31.
go back to reference Chen Y, Squires A, Seifabadi R, Xu S, Agarwal HK, Bernardo M, Pinto PA, Choyke P, Wood B, Tse ZTH (2017) Robotic system for MRI-guided focal laser ablation in the prostate. IEEE/ASME Trans Mechatron 22:107–114CrossRef Chen Y, Squires A, Seifabadi R, Xu S, Agarwal HK, Bernardo M, Pinto PA, Choyke P, Wood B, Tse ZTH (2017) Robotic system for MRI-guided focal laser ablation in the prostate. IEEE/ASME Trans Mechatron 22:107–114CrossRef
Metadata
Title
MR-conditional steerable needle robot for intracerebral hemorrhage removal
Authors
Yue Chen
Isuru S. Godage
Saikat Sengupta
Cindy Lin Liu
Kyle D. Weaver
Eric J. Barth
Publication date
01-01-2019
Publisher
Springer International Publishing
Published in
International Journal of Computer Assisted Radiology and Surgery / Issue 1/2019
Print ISSN: 1861-6410
Electronic ISSN: 1861-6429
DOI
https://doi.org/10.1007/s11548-018-1854-z

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