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International Journal of Computer Assisted Radiology and Surgery
Published in: International Journal of Computer Assisted Radiology and Surgery 4/2013

01-07-2013 | Original Article

The Medical Imaging Interaction Toolkit: challenges and advances

10 years of open-source development

Authors: Marco Nolden, Sascha Zelzer, Alexander Seitel, Diana Wald, Michael Müller, Alfred M. Franz, Daniel Maleike, Markus Fangerau, Matthias Baumhauer, Lena Maier-Hein, Klaus H. Maier-Hein, Hans -Peter Meinzer, Ivo Wolf

Published in: International Journal of Computer Assisted Radiology and Surgery | Issue 4/2013

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Abstract

Purpose

   The Medical Imaging Interaction Toolkit (MITK) has been available as open-source software for almost 10 years now. In this period the requirements of software systems in the medical image processing domain have become increasingly complex. The aim of this paper is to show how MITK evolved into a software system that is able to cover all steps of a clinical workflow including data retrieval, image analysis, diagnosis, treatment planning, intervention support, and treatment control.

Methods

   MITK provides modularization and extensibility on different levels. In addition to the original toolkit, a module system, micro services for small, system-wide features, a service-oriented architecture based on the Open Services Gateway initiative (OSGi) standard, and an extensible and configurable application framework allow MITK to be used, extended and deployed as needed. A refined software process was implemented to deliver high-quality software, ease the fulfillment of regulatory requirements, and enable teamwork in mixed-competence teams.

Results

   MITK has been applied by a worldwide community and integrated into a variety of solutions, either at the toolkit level or as an application framework with custom extensions. The MITK Workbench has been released as a highly extensible and customizable end-user application. Optional support for tool tracking, image-guided therapy, diffusion imaging as well as various external packages (e.g. CTK, DCMTK, OpenCV, SOFA, Python) is available. MITK has also been used in several FDA/CE-certified applications, which demonstrates the high-quality software and rigorous development process.

Conclusions

   MITK provides a versatile platform with a high degree of modularization and interoperability and is well suited to meet the challenging tasks of today’s and tomorrow’s clinically motivated research.
Footnotes
14
The static (de-) initialization order fiasco is well known to any maintainer of a large C++ software system.
 
19
The Eclipse Rich Client Platform is best known as the basis for the Eclipse IDE, http://​wiki.​eclipse.​org/​Rich_​Client_​Platform.
 
20
IEC 62304, B.8.2 Change control: CHANGE REQUESTS can be approved by a change control board or by a manager or technical lead according to the software configuration management plan. Approved CHANGE REQUESTS are made traceable to the actual modification and VERIFICATION of the software. The requirement is that each actual change be linked to a CHANGE REQUEST and that documentation exists to show that the CHANGE REQUEST was approved. The documentation might be change control board minutes, an approval signature, or a record in a database.
 
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Metadata
Title
The Medical Imaging Interaction Toolkit: challenges and advances
10 years of open-source development
Authors
Marco Nolden
Sascha Zelzer
Alexander Seitel
Diana Wald
Michael Müller
Alfred M. Franz
Daniel Maleike
Markus Fangerau
Matthias Baumhauer
Lena Maier-Hein
Klaus H. Maier-Hein
Hans -Peter Meinzer
Ivo Wolf
Publication date
01-07-2013
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Computer Assisted Radiology and Surgery / Issue 4/2013
Print ISSN: 1861-6410
Electronic ISSN: 1861-6429
DOI
https://doi.org/10.1007/s11548-013-0840-8

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